Model of a critical size defect in the New Zealand white rabbit’s tibia
The critical size defect (CSD) has been defined as the smallest intraosseous wound in an animal that will not heal spontaneously within an expected time frame. In the preclinical field of orthopaedics and trauma surgery, CSD has been used as an experimental model for evaluating the effectiveness of...
| Main Authors: | , , , , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/43256/ http://irep.iium.edu.my/43256/1/2-_Poster_2_-_Model_of_CSD.pdf http://irep.iium.edu.my/43256/4/Model_critical_size_defect.pdf |
| _version_ | 1848782414630879232 |
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| author | Mohamed Amin, Mohamed Azril Che Seman, Che Nor Zarida Awang, Mohd Shukrimi Zakaria@Mohamad, Zamzuri Mohd Yusof, Nazri Buyong, Zunariah Mohd Khir, Zafirah |
| author_facet | Mohamed Amin, Mohamed Azril Che Seman, Che Nor Zarida Awang, Mohd Shukrimi Zakaria@Mohamad, Zamzuri Mohd Yusof, Nazri Buyong, Zunariah Mohd Khir, Zafirah |
| author_sort | Mohamed Amin, Mohamed Azril |
| building | IIUM Repository |
| collection | Online Access |
| description | The critical size defect (CSD) has been defined as the smallest intraosseous wound in an animal that will not heal spontaneously within an expected time frame. In the preclinical field of orthopaedics and trauma surgery, CSD has been used as an experimental model for evaluating the effectiveness of newly developed biomaterials. In vivo investigation is important to evaluate the biocompatibility of biomaterial before clinical application. Therefore, the aim of this study is to demonstrate the technical protocol of CSD in rabbit’s tibia for in vivo investigation of new synthetic bone materials. |
| first_indexed | 2025-11-14T16:05:05Z |
| format | Proceeding Paper |
| id | iium-43256 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:05:05Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-432562017-10-19T02:19:54Z http://irep.iium.edu.my/43256/ Model of a critical size defect in the New Zealand white rabbit’s tibia Mohamed Amin, Mohamed Azril Che Seman, Che Nor Zarida Awang, Mohd Shukrimi Zakaria@Mohamad, Zamzuri Mohd Yusof, Nazri Buyong, Zunariah Mohd Khir, Zafirah Q Science (General) R Medicine (General) The critical size defect (CSD) has been defined as the smallest intraosseous wound in an animal that will not heal spontaneously within an expected time frame. In the preclinical field of orthopaedics and trauma surgery, CSD has been used as an experimental model for evaluating the effectiveness of newly developed biomaterials. In vivo investigation is important to evaluate the biocompatibility of biomaterial before clinical application. Therefore, the aim of this study is to demonstrate the technical protocol of CSD in rabbit’s tibia for in vivo investigation of new synthetic bone materials. 2015-06-02 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/43256/1/2-_Poster_2_-_Model_of_CSD.pdf application/pdf en http://irep.iium.edu.my/43256/4/Model_critical_size_defect.pdf Mohamed Amin, Mohamed Azril and Che Seman, Che Nor Zarida and Awang, Mohd Shukrimi and Zakaria@Mohamad, Zamzuri and Mohd Yusof, Nazri and Buyong, Zunariah and Mohd Khir, Zafirah (2015) Model of a critical size defect in the New Zealand white rabbit’s tibia. In: 45th Malaysian Orthopaedic Association Annual Scientific Meeting 2015, 21-24 May 2015, Shangri La Hotel, Kuala Lumpur. (Unpublished) |
| spellingShingle | Q Science (General) R Medicine (General) Mohamed Amin, Mohamed Azril Che Seman, Che Nor Zarida Awang, Mohd Shukrimi Zakaria@Mohamad, Zamzuri Mohd Yusof, Nazri Buyong, Zunariah Mohd Khir, Zafirah Model of a critical size defect in the New Zealand white rabbit’s tibia |
| title | Model of a critical size defect in the New Zealand white rabbit’s tibia |
| title_full | Model of a critical size defect in the New Zealand white rabbit’s tibia |
| title_fullStr | Model of a critical size defect in the New Zealand white rabbit’s tibia |
| title_full_unstemmed | Model of a critical size defect in the New Zealand white rabbit’s tibia |
| title_short | Model of a critical size defect in the New Zealand white rabbit’s tibia |
| title_sort | model of a critical size defect in the new zealand white rabbit’s tibia |
| topic | Q Science (General) R Medicine (General) |
| url | http://irep.iium.edu.my/43256/ http://irep.iium.edu.my/43256/1/2-_Poster_2_-_Model_of_CSD.pdf http://irep.iium.edu.my/43256/4/Model_critical_size_defect.pdf |