Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats
Objectives: To study the effects of Eurycoma Longifolia jack (E.L.) root extract on the serum leptin and testosterone levels of male rats. Methodology: Mature male Albino Wistar rats were used in this study. Serum leptin and testosterone ;levels were analyzed before receiving treatment (control gr...
| Main Authors: | , , , , , |
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| Format: | Proceeding Paper |
| Language: | English |
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2015
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| Online Access: | http://irep.iium.edu.my/42547/ http://irep.iium.edu.my/42547/1/42547.pdf |
| _version_ | 1848782286896496640 |
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| author | Faisal, Ghasak Ghazi Mustafa Al-Ahmad, Basma Ezzat Najmuldeen, Ghazi Faisal Mustafa, Nazih Shaban Al-Ani, Ali Sabri Radeef Althunibat, Osama Yousef |
| author_facet | Faisal, Ghasak Ghazi Mustafa Al-Ahmad, Basma Ezzat Najmuldeen, Ghazi Faisal Mustafa, Nazih Shaban Al-Ani, Ali Sabri Radeef Althunibat, Osama Yousef |
| author_sort | Faisal, Ghasak Ghazi |
| building | IIUM Repository |
| collection | Online Access |
| description | Objectives: To study the effects of Eurycoma Longifolia jack (E.L.) root extract on the serum leptin and testosterone levels of male rats. Methodology: Mature male Albino Wistar rats were used in this study. Serum leptin and testosterone ;levels were analyzed before receiving treatment (control group), then the rats were divided into two groups. Group A received 5mg/kg twice daily of pure E.L. root extract. Group B received 10mg/kg twice daily of the same extract. The duration of treatment was 6 weeks for both groups at the end of which, serum leptin and testosterone levels of both groups were analyzed again. Results: The mean serum leptin and testosterone levels for the control group were 1.13ng/ml, 0.79ng/ml. While for group A were1.08ng/ml, 0.98ng/ml and for Group B were 0.89ng/ml,1.75ng/ml respectively. Statistical analysis showed that the serum leptin level of group B was significantly lower than that of control group (p<0.001) and group A(p<0.05). On the other hand, no significant difference in serum leptin levels was observed between the control group and group A. The serum testosterone level was significantly higher in group B than control and group A while group A did not show a statistically significant difference than control. Conclusion: E.L. root extract can significantly decrease serum leptin and increase serum testosterone levels and these effects are dose dependant. |
| first_indexed | 2025-11-14T16:03:03Z |
| format | Proceeding Paper |
| id | iium-42547 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:03:03Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-425472018-12-12T04:13:58Z http://irep.iium.edu.my/42547/ Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats Faisal, Ghasak Ghazi Mustafa Al-Ahmad, Basma Ezzat Najmuldeen, Ghazi Faisal Mustafa, Nazih Shaban Al-Ani, Ali Sabri Radeef Althunibat, Osama Yousef RB Pathology Objectives: To study the effects of Eurycoma Longifolia jack (E.L.) root extract on the serum leptin and testosterone levels of male rats. Methodology: Mature male Albino Wistar rats were used in this study. Serum leptin and testosterone ;levels were analyzed before receiving treatment (control group), then the rats were divided into two groups. Group A received 5mg/kg twice daily of pure E.L. root extract. Group B received 10mg/kg twice daily of the same extract. The duration of treatment was 6 weeks for both groups at the end of which, serum leptin and testosterone levels of both groups were analyzed again. Results: The mean serum leptin and testosterone levels for the control group were 1.13ng/ml, 0.79ng/ml. While for group A were1.08ng/ml, 0.98ng/ml and for Group B were 0.89ng/ml,1.75ng/ml respectively. Statistical analysis showed that the serum leptin level of group B was significantly lower than that of control group (p<0.001) and group A(p<0.05). On the other hand, no significant difference in serum leptin levels was observed between the control group and group A. The serum testosterone level was significantly higher in group B than control and group A while group A did not show a statistically significant difference than control. Conclusion: E.L. root extract can significantly decrease serum leptin and increase serum testosterone levels and these effects are dose dependant. 2015 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/42547/1/42547.pdf Faisal, Ghasak Ghazi and Mustafa Al-Ahmad, Basma Ezzat and Najmuldeen, Ghazi Faisal and Mustafa, Nazih Shaban and Al-Ani, Ali Sabri Radeef and Althunibat, Osama Yousef (2015) Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats. In: International Conference on Natural Products 2015, 24-25 March 2015, Double Tree by Hilton, Johor Bahru. (Unpublished) |
| spellingShingle | RB Pathology Faisal, Ghasak Ghazi Mustafa Al-Ahmad, Basma Ezzat Najmuldeen, Ghazi Faisal Mustafa, Nazih Shaban Al-Ani, Ali Sabri Radeef Althunibat, Osama Yousef Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats |
| title | Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats |
| title_full | Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats |
| title_fullStr | Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats |
| title_full_unstemmed | Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats |
| title_short | Changes in leptin and testosterone hormones associated with Eurycoma Longifolia jack (Tongkat ali) root extract consumption in male rats |
| title_sort | changes in leptin and testosterone hormones associated with eurycoma longifolia jack (tongkat ali) root extract consumption in male rats |
| topic | RB Pathology |
| url | http://irep.iium.edu.my/42547/ http://irep.iium.edu.my/42547/1/42547.pdf |