Biochemical effects of Nigella sativa seeds in diabetic rats
Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydropero...
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| Format: | Article |
| Language: | English |
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National Institute of Science Communication and Information Resources (NISCAIR), India.
2006
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| Online Access: | http://irep.iium.edu.my/40985/ http://irep.iium.edu.my/40985/1/Biochemical_effects_of_Nigella_sativa_seeds_in_diabetic_rats..pdf |
| _version_ | 1848782036811120640 |
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| author | Ahmed, Qamar Uddin |
| author_facet | Ahmed, Qamar Uddin |
| author_sort | Ahmed, Qamar Uddin |
| building | IIUM Repository |
| collection | Online Access |
| description | Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxidant enzymes like catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase in liver and kidney. The results confirm the antidiabetic activity of N. sativa seeds extract and suggest that because of its antioxidant effects its administration may be useful in controlling the diabetic complications in experimental diabetic rats. |
| first_indexed | 2025-11-14T15:59:05Z |
| format | Article |
| id | iium-40985 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:59:05Z |
| publishDate | 2006 |
| publisher | National Institute of Science Communication and Information Resources (NISCAIR), India. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-409852015-03-04T02:27:49Z http://irep.iium.edu.my/40985/ Biochemical effects of Nigella sativa seeds in diabetic rats Ahmed, Qamar Uddin Q Science (General) Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxidant enzymes like catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase in liver and kidney. The results confirm the antidiabetic activity of N. sativa seeds extract and suggest that because of its antioxidant effects its administration may be useful in controlling the diabetic complications in experimental diabetic rats. National Institute of Science Communication and Information Resources (NISCAIR), India. 2006-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/40985/1/Biochemical_effects_of_Nigella_sativa_seeds_in_diabetic_rats..pdf Ahmed, Qamar Uddin (2006) Biochemical effects of Nigella sativa seeds in diabetic rats. Indian Journal of Experimental Biology , 44 (9). pp. 745-748. ISSN 0975-1009 http://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb2k6/ijep_sept06.asp |
| spellingShingle | Q Science (General) Ahmed, Qamar Uddin Biochemical effects of Nigella sativa seeds in diabetic rats |
| title | Biochemical effects of Nigella sativa seeds in diabetic rats |
| title_full | Biochemical effects of Nigella sativa seeds in diabetic rats |
| title_fullStr | Biochemical effects of Nigella sativa seeds in diabetic rats |
| title_full_unstemmed | Biochemical effects of Nigella sativa seeds in diabetic rats |
| title_short | Biochemical effects of Nigella sativa seeds in diabetic rats |
| title_sort | biochemical effects of nigella sativa seeds in diabetic rats |
| topic | Q Science (General) |
| url | http://irep.iium.edu.my/40985/ http://irep.iium.edu.my/40985/ http://irep.iium.edu.my/40985/1/Biochemical_effects_of_Nigella_sativa_seeds_in_diabetic_rats..pdf |