Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
Purpose:To investigate total retinal blood flow (TRBF) and retinal blood flow (RBF) in the superior (S) and the inferior (I) retinal hemifields in patients with primary open angle glaucoma (POAG) both with and without disc hemorrhage (DH). Methods:RBF measurements were obtained from 10 POAG with DH...
| Main Authors: | , , , , , , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
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2014
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| Online Access: | http://irep.iium.edu.my/40376/ http://irep.iium.edu.my/40376/1/Abstract_Nadia_FYA_ARVO_2014.pdf http://irep.iium.edu.my/40376/4/ARVO_2014.pdf |
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| author | Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G |
| author_facet | Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G |
| author_sort | Hudson, Christopher |
| building | IIUM Repository |
| collection | Online Access |
| description | Purpose:To investigate total retinal blood flow (TRBF) and retinal blood flow (RBF) in the superior (S) and the inferior (I) retinal hemifields in patients with primary open angle glaucoma (POAG) both with and without disc hemorrhage (DH).
Methods:RBF measurements were obtained from 10 POAG with DH (mean age 71.7, SD=7.39; 9 females)and 10 age matched POAG without DH (mean age 70, SD = 5.27; 6 females) using Doppler SD-OCT (RTVue; Optovue Inc, Fremont, CA, USA) as well as bi-directional laser Doppler flowmetry with
densitometry (CLBF-100, Canon, Tokyo, Japan). TRBF measurements were compared between groups, within group for SRBF and IRBF, and for inter-ocular asymmetry (ANOVA; p<0.05). Correlation between TRBF and age, and TRBF and Mean Deviation of Humphrey automated perimetry were also analyzed.
Results:Venous TRBF in the POAG with DH group (n=10, 27.1 μl/min, SD 7) was significantly lower than in the age-matched POAG without DH group (n=10, 38.83 μl/min, SD 10.66, p=0.009). RBF was not significantly different between the superior and inferior hemifields for either POAG with DH (p=0.763) or POAG without DH (p=0.481). In the POAG with DH group, venous TRBF was significantly lower in the DH eye (n=8, 28.73 μl/min, SD 6.87) compared to the contralateral eye without DH (n=8, 38.44 μl/min, SD 7.11,
p=0.015). There was no significant difference between IOP, MD, BP, HR and MOPP between the POAG with and without DH groups. Also, there was no significant relationship between age or MD index of automated static perimetry with venous TRBF for the POAG with, and without DH group.
Conclusions:Venous TRBF was significantly lower in the POAG with DH group compared to both the POAG without DH group and the contralateral eye of the POAG with DH group. There was no within eye asymmetry when comparing SRBF and IRBF either with or without DH, or when comparing the hemifield
with DH to that without. |
| first_indexed | 2025-11-14T15:57:35Z |
| format | Proceeding Paper |
| id | iium-40376 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T15:57:35Z |
| publishDate | 2014 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-403762014-12-30T01:53:04Z http://irep.iium.edu.my/40376/ Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G RE Ophthalmology Purpose:To investigate total retinal blood flow (TRBF) and retinal blood flow (RBF) in the superior (S) and the inferior (I) retinal hemifields in patients with primary open angle glaucoma (POAG) both with and without disc hemorrhage (DH). Methods:RBF measurements were obtained from 10 POAG with DH (mean age 71.7, SD=7.39; 9 females)and 10 age matched POAG without DH (mean age 70, SD = 5.27; 6 females) using Doppler SD-OCT (RTVue; Optovue Inc, Fremont, CA, USA) as well as bi-directional laser Doppler flowmetry with densitometry (CLBF-100, Canon, Tokyo, Japan). TRBF measurements were compared between groups, within group for SRBF and IRBF, and for inter-ocular asymmetry (ANOVA; p<0.05). Correlation between TRBF and age, and TRBF and Mean Deviation of Humphrey automated perimetry were also analyzed. Results:Venous TRBF in the POAG with DH group (n=10, 27.1 μl/min, SD 7) was significantly lower than in the age-matched POAG without DH group (n=10, 38.83 μl/min, SD 10.66, p=0.009). RBF was not significantly different between the superior and inferior hemifields for either POAG with DH (p=0.763) or POAG without DH (p=0.481). In the POAG with DH group, venous TRBF was significantly lower in the DH eye (n=8, 28.73 μl/min, SD 6.87) compared to the contralateral eye without DH (n=8, 38.44 μl/min, SD 7.11, p=0.015). There was no significant difference between IOP, MD, BP, HR and MOPP between the POAG with and without DH groups. Also, there was no significant relationship between age or MD index of automated static perimetry with venous TRBF for the POAG with, and without DH group. Conclusions:Venous TRBF was significantly lower in the POAG with DH group compared to both the POAG without DH group and the contralateral eye of the POAG with DH group. There was no within eye asymmetry when comparing SRBF and IRBF either with or without DH, or when comparing the hemifield with DH to that without. 2014 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/40376/1/Abstract_Nadia_FYA_ARVO_2014.pdf application/pdf en http://irep.iium.edu.my/40376/4/ARVO_2014.pdf Hudson, Christopher and Espahbodi, Nadia and Shahidi, Ayda M and Yusof, Firdaus and Cheng, Richard and Jong, Monica and Graham, Trope and Buys, Yvonne M and Flanagan, John G (2014) Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage. In: ARVO Annual Meeting 2014, May 6th, 2014, Orlando, FL, USA. http://www.arvo.org/webs/am2014/abstract/sessions/320.pdf |
| spellingShingle | RE Ophthalmology Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage |
| title | Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage |
| title_full | Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage |
| title_fullStr | Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage |
| title_full_unstemmed | Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage |
| title_short | Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage |
| title_sort | retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage |
| topic | RE Ophthalmology |
| url | http://irep.iium.edu.my/40376/ http://irep.iium.edu.my/40376/ http://irep.iium.edu.my/40376/1/Abstract_Nadia_FYA_ARVO_2014.pdf http://irep.iium.edu.my/40376/4/ARVO_2014.pdf |