Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents
Several studies have demonstrated that adiponectin has strong association with metabolic syndrome and its factors like obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. A total 152 subjects were registered in this study. Among the respondents 76 were with metabo...
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| Format: | Article |
| Language: | English |
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Science and Education Publishing
2014
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| Online Access: | http://irep.iium.edu.my/40261/ http://irep.iium.edu.my/40261/1/Adiponectin_Correlates_in_Malaysian_s-ajcmr-2-6-1.pdf |
| _version_ | 1848781922508996608 |
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| author | Md Aris, Mohd Aznan Khattak, Muhammad Muzaffar Ali Khan Abdullah, Nor Zamzila Mohd Rus, Razman Draman, Samsul |
| author_facet | Md Aris, Mohd Aznan Khattak, Muhammad Muzaffar Ali Khan Abdullah, Nor Zamzila Mohd Rus, Razman Draman, Samsul |
| author_sort | Md Aris, Mohd Aznan |
| building | IIUM Repository |
| collection | Online Access |
| description | Several studies have demonstrated that adiponectin has strong association with metabolic syndrome and its factors like obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. A total 152 subjects were registered in this study. Among the respondents 76 were with metabolic syndrome (based on the criteria of the International Diabetes Federation (IDF) world-wide definition) and another 76 matching healthy respondents. The factors which were studied for possible differences and association include central obesity (body mass index (BMI) & waist circumference (WC), hypertension (systolic blood pressure (SBP), diastolic blood pressure (DBP), dyslipidemia (total cholesterol (Tc), high density lipoprotein Cholesterol (HDL-c), low density lipoprotein Cholesterol (LDL-c), Triglyceride (TG) and Adiponectin (AD), fasting plasma glucose and history of smoking. The data collected was statistically analyzed using SPSS statistical software version 12.0. Two tests were performed including paired t-test and Pearson correlation analysis. The collected data revealed some interesting differences for the healthy and metabolic syndrome respondents. There were significant (P<0.01) differences for central obesity and hypertension. There were also significant (P<0.01, P<0.1, P<0.01) differences for TG, HDL and fasting plasma glucose. More importantly, AD concentration was significantly (P<0.05) higher in normal healthy respondents. The AD showed strong negative association (r = - 2.91, P<0.001) with FBG and positive association (r = 2.89, P<0.001) with HDL-c. The present study provides baseline information on the predication of metabolic syndrome in Malaysian population. |
| first_indexed | 2025-11-14T15:57:16Z |
| format | Article |
| id | iium-40261 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:57:16Z |
| publishDate | 2014 |
| publisher | Science and Education Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-402612016-02-25T03:07:32Z http://irep.iium.edu.my/40261/ Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents Md Aris, Mohd Aznan Khattak, Muhammad Muzaffar Ali Khan Abdullah, Nor Zamzila Mohd Rus, Razman Draman, Samsul R Medicine (General) Several studies have demonstrated that adiponectin has strong association with metabolic syndrome and its factors like obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. A total 152 subjects were registered in this study. Among the respondents 76 were with metabolic syndrome (based on the criteria of the International Diabetes Federation (IDF) world-wide definition) and another 76 matching healthy respondents. The factors which were studied for possible differences and association include central obesity (body mass index (BMI) & waist circumference (WC), hypertension (systolic blood pressure (SBP), diastolic blood pressure (DBP), dyslipidemia (total cholesterol (Tc), high density lipoprotein Cholesterol (HDL-c), low density lipoprotein Cholesterol (LDL-c), Triglyceride (TG) and Adiponectin (AD), fasting plasma glucose and history of smoking. The data collected was statistically analyzed using SPSS statistical software version 12.0. Two tests were performed including paired t-test and Pearson correlation analysis. The collected data revealed some interesting differences for the healthy and metabolic syndrome respondents. There were significant (P<0.01) differences for central obesity and hypertension. There were also significant (P<0.01, P<0.1, P<0.01) differences for TG, HDL and fasting plasma glucose. More importantly, AD concentration was significantly (P<0.05) higher in normal healthy respondents. The AD showed strong negative association (r = - 2.91, P<0.001) with FBG and positive association (r = 2.89, P<0.001) with HDL-c. The present study provides baseline information on the predication of metabolic syndrome in Malaysian population. Science and Education Publishing 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/40261/1/Adiponectin_Correlates_in_Malaysian_s-ajcmr-2-6-1.pdf Md Aris, Mohd Aznan and Khattak, Muhammad Muzaffar Ali Khan and Abdullah, Nor Zamzila and Mohd Rus, Razman and Draman, Samsul (2014) Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents. American Journal of Clinical Medicine Research, 2 (6). pp. 106-110. ISSN 2328-4005 (P), 2328-403X (o) http://pubs.sciepub.com/ajcmr/2/6/1/ 10.12691/ajcmr-2-6-1 |
| spellingShingle | R Medicine (General) Md Aris, Mohd Aznan Khattak, Muhammad Muzaffar Ali Khan Abdullah, Nor Zamzila Mohd Rus, Razman Draman, Samsul Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents |
| title | Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents |
| title_full | Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents |
| title_fullStr | Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents |
| title_full_unstemmed | Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents |
| title_short | Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents |
| title_sort | adiponectin correlates in malaysians: a comparison of metabolic syndrome and healthy respondents |
| topic | R Medicine (General) |
| url | http://irep.iium.edu.my/40261/ http://irep.iium.edu.my/40261/ http://irep.iium.edu.my/40261/ http://irep.iium.edu.my/40261/1/Adiponectin_Correlates_in_Malaysian_s-ajcmr-2-6-1.pdf |