Formulation and stability testing of gentamicin-Nigella sativa emulsions for osteo-healing application

QR Code

Formulation and stability testing of gentamicin-Nigella sativa emulsions for osteo-healing application

An alternative osteo-healing formulation with osteo-healing properties was formulated by combining gentamicin and Nigella sativa (N. sativa) oil in an emulsion to reduce gentamicin toxicity effect over prolonged use in osteo-infection treatment. This work aims to test the aqueous solubility and phys...

Full description

Bibliographic Details
Main Authors:	Yusof, Fathin Athirah, Yaacob, Khairul Ikhwan, Mohd Yusof, Nazri, Mohamed, Farahidah, Mohd Shafri, Mohd Affendi
Format:	Proceeding Paper
Language:	English English
Published:	2014
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/39647/ http://irep.iium.edu.my/39647/1/ICIP_-_Fathin_Athirah_%28G1313984%29_horizontal2.pdf http://irep.iium.edu.my/39647/4/formulation_and_stability.pdf

Similar Items

Formulation and stability testing of Gentamicin-N. sativa fusion emulsions for osteo-healing application
by: Mohd Shafri, Mohd Affendi, et al.
Published: (2014)

Preparation and characterization of gentamicin-nigella sativa oil fusion microemulsions for future greener pharmaceutical
by: Mohd Nor, Nurul Hafizah, et al.
Published: (2014)

In vitro antimicrobial effect of Gentamicin-N.sativa fusion emulsion against biofilm producing strain S.aureus, P.aeruginosa and S.epidermidis
by: Yaacob, Khairul Ikhwan, et al.
Published: (2014)

Compatibility characterization of Gentamicin-Nigella sativa fusion as a future greener pharmaceutical intended for ortheopaedic infection
by: Harun Ismail, Ahmad Fahmi, et al.
Published: (2014)

Synergistic effects of new gentamicin-N.sativa emulsion against gentamicin-resistant, biofilm bacteria of osteomyelitis
by: Yaacob, Khairul Ikhwan, et al.
Published: (2014)

Confocal laser scanning microscope analysis on post-biofilm assessment of biofilmproducing osteomyelitic staphylococcus aureus treated with new gentamicin-nigella sativa fusion emulsion (GNFE)
by: Yaacob, Khairul Ikhwan, et al.
Published: (2015)

Confocal laser screening microscope analysis on post-biofilm assessment of biofilm-producing osteomyelitic staphylococcus aureus treated with new Gentamicin-nigella sativa Fusion Emulsion (GNFE)
by: Mohd Shafri, Mohd Affendi, et al.
Published: (2015)

Development and optimization of gentamicin-Nigella sativa oil emulsion (GNE) using central-composite design approach
by: Mohd Shafri, Mohd Affendi, et al.
Published: (2016)

The potential of novel gentamicin-black seed oil (GBSO) fusion emulsion in treating biofilm infection
by: Mohd Shafri, Mohd Affendi, et al.
Published: (2015)

In-vitro test of gentamicin-nigella sativa microspheres as novel drug delivery system for osteomyelitic treatment
by: Mohd Shafri, Mohd Affendi, et al.
Published: (2016)

Screening the influencing factors of gentamicin-N. sativa oil emulsions (GNE) characteristic using Plackett-Burmann design (PBD)
by: Adina, Anugerah Budipratama, et al.
Published: (2017)

Spectrophotometric determination of gentamicin loaded PLGA microparticles and method validation via ninhydrin-gentamicin complex as a rapid quantification approach
by: Harun @ Ismail, Ahmad Fahmi, et al.
Published: (2016)

Stability testing of oil-in-water emulsion of Syzygium aromaticum (clove)
by: Abdul Ghafar, Syafiq, et al.
Published: (2015)

Preparation and characterization of nigella sativa microemulsions
by: Mohd Nor, Nurul Hafizah, et al.
Published: (2014)

The effect of Nigella sativa extract on mouse oocyte activation
by: Abdul Rahman, Suzanah, et al.
Published: (2014)

Stability testing of oil-in-water (o/w) emulsion of Szygium aromaticum (Cloves)
by: Abdul Ghafar, Syafiq, et al.
Published: (2014)

Method development and validation using UV spectrophotometry for Nigella sativa oil microparticles quantification
by: Harun Ismail, Ahmad Fahmi, et al.
Published: (2015)

Antibiotic-Nigella Sativa Fusion (ANF) as a novel approach intended for the treatment against bacteria forming biofilm in osteomyelitis
by: Mohamed, Farahidah, et al.
Published: (2015)

Cellular uptake of Nigella sativa oil-PLGA microparticle by PC12 cell line
by: Doolaanea, Abd Almonem, et al.
Published: (2014)

Topical co-delivery of indomethacin and nigella sativa L. essential oil in poly-cappa-caprolactone nanoparticles: in vitro study of anti-inflammatory activity
by: Badri, Waisudin, et al.
Published: (2018)

Fabrication of gentamicin and N. sativa oil loaded PLGA microspheres and the comparison of extended release profile between powdered and compressed forms
by: Mohamed, Farahidah, et al.
Published: (2016)

Anticancer effects of eurycoma longifolia, Nigella sativa and hibiscus sabdariffa on ovarian cancer cells
by: Abdullah, 'Afif Raihan, et al.
Published: (2016)

The chemopreventive effects of Nigella sativa extract and Thymoquinone in a paternal toxicity study
by: Abdul Samat, Nadia Hanis, et al.
Published: (2015)

Antimicrobial, remineralising and protective effects of doxycycline-n. Sativa-eugenol (DNE) emulsion for peridontitis
by: Mohd Shafri, Mohd Affendi
Published: (2017)

The potential of nigella sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure
by: Abdul Samat, Nadia Hanis, et al.
Published: (2016)

Potential effects of Nigella sativa and thymoquinone on the foetal development of cyclophosphamide-treated male mice
by: Abdul Rahman, Suzanah, et al.
Published: (2016)

The potential of Nigella Sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure
by: Abdul Samat, Nadia Hanis, et al.
Published: (2016)

Characterization study of inggu (ferula asafetida) resin
by: Zulkply, Siti Mariam, et al.
Published: (2014)

Investigating the potential of Nigella sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure to cyclophosphamide
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Preparation and characterization of nigella sative microemulsions
by: Mohd Nor, Nor Hafizah, et al.
Published: (2014)

Prophylactic effects of Nigella sativa extract and thymoquinone against cyclophosphamide-induced sperm head abnormalities and chromatin instability in mice
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Effect of N. Sativa on Characteristics of gentamicin-loaded chitosan/PLGA microspheres
by: Mohamad Shukri, Najihah, et al.
Published: (2012)

Palm olein emulsions potential vehicles for drug delivery
by: Mohd Nawi, Mohamed Sufian, et al.
Published: (2017)

Co-encapsulation of NIgella sativa oil with plasmid DNA into biodegradable PLGA nanoparticle
by: Doolaane, Abd Monem, et al.
Published: (2013)

Antimicrobial activity of nigella sativa seed extract
by: Nor’ Aishah Hasan,, et al.
Published: (2013)

Sub-acute toxicity of black seed (Nigella sativa) and honey mixture
by: Wong, Pei Lou, et al.
Published: (2018)

Stability of inggu (ferula asafetida) in different excipients
by: Mukhtar, Nor Izzah, et al.
Published: (2014)

Cellular uptake of nigella sativa oil-PLGA microparticle by PC-12 cell line
by: Doolaanea, Abd Almonem, et al.
Published: (2014)

Extraction of nigella sativa using modern hydrodistillation technique
by: Mohd Aizudin, Abd Aziz
Published: (2006)

Potential surface active properties of Nigella sativa
by: Said, Siti Nurfajariah, et al.
Published: (2011)