Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice
The aim of the current study was to investigate changes in the reproductive parameters during stress and the impact of thymoquinone during the period. The effects of stress were measured through immobilisation stress on mice. Group I was administered normal saline daily via intraperitoneal injection...
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| Format: | Article |
| Language: | English |
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Applied and Natural Science Foundation
2014
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| Online Access: | http://irep.iium.edu.my/39098/ http://irep.iium.edu.my/39098/1/JANS-Suzanah.pdf |
| _version_ | 1848781723435794432 |
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| author | Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera |
| author_facet | Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera |
| author_sort | Abdul Rahman, Suzanah |
| building | IIUM Repository |
| collection | Online Access |
| description | The aim of the current study was to investigate changes in the reproductive parameters during stress and the impact of thymoquinone during the period. The effects of stress were measured through immobilisation stress on mice. Group I was administered normal saline daily via intraperitoneal injection while Groups II and III were subjected to 2 and 6 hours of immobilisation stress respectively. Groups IV and V were subjected to stress for 2 and 6 hours respectively followed by intraperitoneal injection of 10 mg/kg thymoquinone which was continued on alternate days. The level of significance was set at p<0.05 and statistical analysis showed significant difference in testicular weight of mice in groups II and III compared to the controls but no significant difference was obtained for sperm count between all groups. Sperm motility, however, was significantly different among the groups under stress for 2 and 6 hours and that of 6 hours with the treatment of thymoquinone when compared to the controls. The histology of the testes also indicated a few alterations in comparison to the controls in the germinal epithelium and spermatogenic pattern in groups III and V. |
| first_indexed | 2025-11-14T15:54:06Z |
| format | Article |
| id | iium-39098 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:54:06Z |
| publishDate | 2014 |
| publisher | Applied and Natural Science Foundation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-390982015-08-31T17:59:17Z http://irep.iium.edu.my/39098/ Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera QP Physiology R Medicine (General) The aim of the current study was to investigate changes in the reproductive parameters during stress and the impact of thymoquinone during the period. The effects of stress were measured through immobilisation stress on mice. Group I was administered normal saline daily via intraperitoneal injection while Groups II and III were subjected to 2 and 6 hours of immobilisation stress respectively. Groups IV and V were subjected to stress for 2 and 6 hours respectively followed by intraperitoneal injection of 10 mg/kg thymoquinone which was continued on alternate days. The level of significance was set at p<0.05 and statistical analysis showed significant difference in testicular weight of mice in groups II and III compared to the controls but no significant difference was obtained for sperm count between all groups. Sperm motility, however, was significantly different among the groups under stress for 2 and 6 hours and that of 6 hours with the treatment of thymoquinone when compared to the controls. The histology of the testes also indicated a few alterations in comparison to the controls in the germinal epithelium and spermatogenic pattern in groups III and V. Applied and Natural Science Foundation 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/39098/1/JANS-Suzanah.pdf Abdul Rahman, Suzanah and Mohamed Anwar, Norul Athirah and Shaik , Sadak Basha and Kamarzaman, Saheera (2014) Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice. Journal of Applied and Natural Science, 6 (1). pp. 1-5. ISSN 0974-9411 (P); 2231-5209 (O) http://www.ansfoundation.org/abstract/abstract611 |
| spellingShingle | QP Physiology R Medicine (General) Abdul Rahman, Suzanah Mohamed Anwar, Norul Athirah Shaik , Sadak Basha Kamarzaman, Saheera Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice |
| title | Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice |
| title_full | Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice |
| title_fullStr | Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice |
| title_full_unstemmed | Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice |
| title_short | Impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice |
| title_sort | impact of thymoquinone supplementation on immobilisation stress-induced changes in reproductive characteristics of male mice |
| topic | QP Physiology R Medicine (General) |
| url | http://irep.iium.edu.my/39098/ http://irep.iium.edu.my/39098/ http://irep.iium.edu.my/39098/1/JANS-Suzanah.pdf |