Lab-on-a-chip approaches for space-biology research

Lab-on-a-chip (LOC) systems with electrochemical sensing capability can provide real-time physiological measurements in spaceflight environments. They are easily miniaturized and integrated with existing space hardware systems. To reduce crew time during spaceflight research, the systems can be made...

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Main Authors: Wan Salim, Wan Wardatul Amani, Park, Joon Hyeong, Ul Haque, Aeraj, Porterfield, David Marshall
Other Authors: Rampelotto, Pabulo Henrique
Format: Article
Language:English
Published: Bentham Science Publishers 2013
Subjects:
Online Access:http://irep.iium.edu.my/39096/
http://irep.iium.edu.my/39096/1/0005RPTST.pdf
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author Wan Salim, Wan Wardatul Amani
Park, Joon Hyeong
Ul Haque, Aeraj
Porterfield, David Marshall
author2 Rampelotto, Pabulo Henrique
author_facet Rampelotto, Pabulo Henrique
Wan Salim, Wan Wardatul Amani
Park, Joon Hyeong
Ul Haque, Aeraj
Porterfield, David Marshall
author_sort Wan Salim, Wan Wardatul Amani
building IIUM Repository
collection Online Access
description Lab-on-a-chip (LOC) systems with electrochemical sensing capability can provide real-time physiological measurements in spaceflight environments. They are easily miniaturized and integrated with existing space hardware systems. To reduce crew time during spaceflight research, the systems can be made autonomous and simple to use. Research and development of electrochemical-sensing LOC systems are still in progress for fundamental space-biology research in microgravity. Ion-selective electrodes as electrochemical sensors are miniaturized in an all-solid-state format for easier packaging and handling. The design, fabrication, and application of these sensors are discussed, with examples from those developed at the Physiological Sensing Facility (PSF) at Purdue University. The objective of this paper is not to provide an exhaustive review of current LOC systems, but to describe research developments made for the purpose of conducting physiological measurements in microgravity with examples of patents that support space missions.
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institution International Islamic University Malaysia
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spelling iium-390962017-02-23T09:13:20Z http://irep.iium.edu.my/39096/ Lab-on-a-chip approaches for space-biology research Wan Salim, Wan Wardatul Amani Park, Joon Hyeong Ul Haque, Aeraj Porterfield, David Marshall T Technology (General) TA164 Bioengineering Lab-on-a-chip (LOC) systems with electrochemical sensing capability can provide real-time physiological measurements in spaceflight environments. They are easily miniaturized and integrated with existing space hardware systems. To reduce crew time during spaceflight research, the systems can be made autonomous and simple to use. Research and development of electrochemical-sensing LOC systems are still in progress for fundamental space-biology research in microgravity. Ion-selective electrodes as electrochemical sensors are miniaturized in an all-solid-state format for easier packaging and handling. The design, fabrication, and application of these sensors are discussed, with examples from those developed at the Physiological Sensing Facility (PSF) at Purdue University. The objective of this paper is not to provide an exhaustive review of current LOC systems, but to describe research developments made for the purpose of conducting physiological measurements in microgravity with examples of patents that support space missions. Bentham Science Publishers Rampelotto, Pabulo Henrique 2013-11-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/39096/1/0005RPTST.pdf Wan Salim, Wan Wardatul Amani and Park, Joon Hyeong and Ul Haque, Aeraj and Porterfield, David Marshall (2013) Lab-on-a-chip approaches for space-biology research. Recent Patents on Space Technology , 3 (1). pp. 24-39. ISSN 2210-6871 http://www.eurekaselect.com/ 10.2174/18776116112029990010
spellingShingle T Technology (General)
TA164 Bioengineering
Wan Salim, Wan Wardatul Amani
Park, Joon Hyeong
Ul Haque, Aeraj
Porterfield, David Marshall
Lab-on-a-chip approaches for space-biology research
title Lab-on-a-chip approaches for space-biology research
title_full Lab-on-a-chip approaches for space-biology research
title_fullStr Lab-on-a-chip approaches for space-biology research
title_full_unstemmed Lab-on-a-chip approaches for space-biology research
title_short Lab-on-a-chip approaches for space-biology research
title_sort lab-on-a-chip approaches for space-biology research
topic T Technology (General)
TA164 Bioengineering
url http://irep.iium.edu.my/39096/
http://irep.iium.edu.my/39096/
http://irep.iium.edu.my/39096/
http://irep.iium.edu.my/39096/1/0005RPTST.pdf