Formulation and in-vitro characterization of floating sustained-release tablets of metformin hydrochloride

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Formulation and in-vitro characterization of floating sustained-release tablets of metformin hydrochloride

Metformin HCl, a drug from biguanide class, is the most commonly used first-line antihyperglycemic agent in the treatment of NIDDM [1]. The major problems associated with the drug are high dose (1.5-2.0 g/day), frequent dosing due to its shorter biological half-life (1.5-4.9 hr), and low bioavailabi...

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Bibliographic Details
Main Authors:	Senjoti, Faria Gias, Md. Jaffri, Juliana, Mandal, Uttam Kumar
Format:	Proceeding Paper
Language:	English English
Published:	2014
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/38281/ http://irep.iium.edu.my/38281/1/metformin.pdf http://irep.iium.edu.my/38281/2/Binder1.pdf

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