Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials

A pilot-scale production of lipase using palm oil mill effluent (POME) as a fermentation basal medium was carried out, and parameters for immobilization of the produced lipase were optimized. Lipase production in a 300-L bioreactor was performed using two proposed strategies, constant power per volu...

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Main Authors: Asih, Devi Ratna, Alam, Md Zahangir, Salleh, Md. Noor, Salihu, Aliyu
Format: Article
Language:English
English
Published: Japan Oil Chemists' Society 2014
Subjects:
Online Access:http://irep.iium.edu.my/38191/
http://irep.iium.edu.my/38191/1/Paper-JOS-devi.pdf
http://irep.iium.edu.my/38191/4/38191-Pilot-scale%20production%20of%20lipase%20using%20palm%20oil%20mill%20effluent%20as%20a%20basal%20medium_SCOPUS.pdf
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author Asih, Devi Ratna
Alam, Md Zahangir
Salleh, Md. Noor
Salihu, Aliyu
author_facet Asih, Devi Ratna
Alam, Md Zahangir
Salleh, Md. Noor
Salihu, Aliyu
author_sort Asih, Devi Ratna
building IIUM Repository
collection Online Access
description A pilot-scale production of lipase using palm oil mill effluent (POME) as a fermentation basal medium was carried out, and parameters for immobilization of the produced lipase were optimized. Lipase production in a 300-L bioreactor was performed using two proposed strategies, constant power per volume (P/V) and constant tip speed. Moreover, lipase immobilization on different materials was also investigated. Lipase production was performed using liquid-state bioconversion of POME as the medium and Candida cylindracea as the inoculum. The fermentation medium was composed of 1% total suspended solids (TSS) of POME, 0.5% (w/v) peptone, 0.7% (v/v) Tween-80, and 2.2% inoculum. The medium composition was decided on the basis of the medium optimization results of a previous study. The fermentation was carried out for 48 h at 30°C and pH 6. The maximum lipase production was 5.72U/mL and 21.34 U/mL, obtained from the scale-up strategies of constant tip speed and P/V, respectively. Four accessible support materials were screened for their potential use in immobilization. The most suitable support material was found to be activated carbon, with a maximum immobilization of 94%.
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language English
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publisher Japan Oil Chemists' Society
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spelling iium-381912017-08-10T07:21:51Z http://irep.iium.edu.my/38191/ Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials Asih, Devi Ratna Alam, Md Zahangir Salleh, Md. Noor Salihu, Aliyu TP248.13 Biotechnology A pilot-scale production of lipase using palm oil mill effluent (POME) as a fermentation basal medium was carried out, and parameters for immobilization of the produced lipase were optimized. Lipase production in a 300-L bioreactor was performed using two proposed strategies, constant power per volume (P/V) and constant tip speed. Moreover, lipase immobilization on different materials was also investigated. Lipase production was performed using liquid-state bioconversion of POME as the medium and Candida cylindracea as the inoculum. The fermentation medium was composed of 1% total suspended solids (TSS) of POME, 0.5% (w/v) peptone, 0.7% (v/v) Tween-80, and 2.2% inoculum. The medium composition was decided on the basis of the medium optimization results of a previous study. The fermentation was carried out for 48 h at 30°C and pH 6. The maximum lipase production was 5.72U/mL and 21.34 U/mL, obtained from the scale-up strategies of constant tip speed and P/V, respectively. Four accessible support materials were screened for their potential use in immobilization. The most suitable support material was found to be activated carbon, with a maximum immobilization of 94%. Japan Oil Chemists' Society 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/38191/1/Paper-JOS-devi.pdf application/pdf en http://irep.iium.edu.my/38191/4/38191-Pilot-scale%20production%20of%20lipase%20using%20palm%20oil%20mill%20effluent%20as%20a%20basal%20medium_SCOPUS.pdf Asih, Devi Ratna and Alam, Md Zahangir and Salleh, Md. Noor and Salihu, Aliyu (2014) Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials. Journal of Oleo Science, 63 (8). pp. 779-785. ISSN 1345-8957 E-ISSN 1347-3352 http://dx.doi.org/10.5650/jos.ess13187 doi:10.5650/jos.ess13187
spellingShingle TP248.13 Biotechnology
Asih, Devi Ratna
Alam, Md Zahangir
Salleh, Md. Noor
Salihu, Aliyu
Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials
title Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials
title_full Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials
title_fullStr Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials
title_full_unstemmed Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials
title_short Pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials
title_sort pilot-scale production of lipase using palm oil mill effluent as a basal medium and its immobilization by selected materials
topic TP248.13 Biotechnology
url http://irep.iium.edu.my/38191/
http://irep.iium.edu.my/38191/
http://irep.iium.edu.my/38191/
http://irep.iium.edu.my/38191/1/Paper-JOS-devi.pdf
http://irep.iium.edu.my/38191/4/38191-Pilot-scale%20production%20of%20lipase%20using%20palm%20oil%20mill%20effluent%20as%20a%20basal%20medium_SCOPUS.pdf