Subchondral bone plate thickening precedes chondrocyte apoptosis and cartilage degradation in spontaneous animal models of osteoarthritis

QR Code

Subchondral bone plate thickening precedes chondrocyte apoptosis and cartilage degradation in spontaneous animal models of osteoarthritis

Osteoarthritis (OA) is the most common joint disorder characterised by bone remodelling and cartilage degradation and associated with chondrocyte apoptosis. These processes were investigated at 10, 16, 24, and 30 weeks in Dunkin Hartley (DH) and Bristol Strain 2 (BS2) guinea pigs that develop OA spo...

Full description

Bibliographic Details
Main Authors:	Zamli, Zaitunnatakhin, Brown, Kate Robson, Tarlton, John F., Adams, Mike A., Torlot, Georgina E., Cartwright, Charlie, Cook, William A., Vassilevskaja, Kristiina, Sharif, Mohammed
Format:	Article
Language:	English
Published:	Hindawi Publishing Corporation 2014
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/37057/ http://irep.iium.edu.my/37057/1/Subchondral_Bone_Plate_Thickening_Precedes_Chondrocyte_Apoptosis_and_Cartilage_Degradation_in_Spontaneous_Animal_Models_of_Osteoarthritis.pdf

Similar Items

Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous guinea pig models of the disease
by: Zamli, Zaitunnatakhin, et al.
Published: (2013)

Subchondral bone plate remodels more rapidly than trabecular bone in osteoarthritis
by: Zamli, Zaitunnatakhin, et al.
Published: (2015)

Temporal and topographical variation of subchondral bone changes in a spontaneous animal models of osteoarthritis
by: Ahmad Rafani, Fikri, et al.
Published: (2015)

The role of subchondral bone plate porosity during the development of osteoarthritis in guinea pigs
by: Baharuddin, Aina, et al.
Published: (2016)

Differential remodeling of subchondral bone plate and trabecular bone of the tibia in spontaneous animal models of osteoarthritis
by: Zamli, Zaitunnatakhin, et al.
Published: (2018)

Subchondral bone plate changes more rapidly than trabecular bone in osteoarthritis
by: Zamli, Zaitunnatakhin, et al.
Published: (2016)

Chondrocyte apoptosis: a cause or consequence of osteoarthritis?
by: Zamli, Zaitunnatakhin, et al.
Published: (2011)

Association between the subchondral bone plate and articular cartilage thickness during the progression of osteoarthritis in Dunkin Hartley guinea pigs
by: Md Yusof, Nur Azirah, et al.
Published: (2017)

Changes of grip strength, articular cartilage and subchondral bone in monoiodoacetate-induced osteoarthritis in rats
by: Ekeuku, Sophia Ogechi, et al.
Published: (2022)

Structural changes and molecular mechanisms of bone remodelling in two different regions of subchondral bone during early osteoarthritis
by: Akman, Akma Azmiera, et al.
Published: (2018)

Regional and compartmentalized variation of subchondral bone mineralization and microarchitecture in hip osteoarthritis
by: Li, Yunfei, et al.
Published: (2020)

Edible Bird's Nest treatment effects on subchondral bone and articular cartilage changes and synovial fluid proteome profiles in an osteoarthritis rabbit model
by: Syed Sulaiman, Sharifah Zakiah
Published: (2022)

Cytoprotective role of chondrocyte coculturing for enhanced cartilage regeneration
by: Muhammad Faizan Tariq,, et al.
Published: (2024)

The remodelling of tibial trabecular bone in spontaneous animal model of osteoarthritis
by: Akman, Akma Azmiera, et al.
Published: (2018)

Study of morphologic response of chondrocytes to uniaxial compression of articular cartilage
by: Wu, Ping, et al.
Published: (2008)

Structural changes and the differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kb ligand (RANKL) in subchondral bone during the development of osteoarthritis
by: Akman, Akma Azmiera, et al.
Published: (2018)

Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis
by: Prieto-Potin, Iván, et al.
Published: (2015)

Structural changes and the differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kB ligand (RANKL) in subchondral bone during the development of osteoarthritis
by: AKMAN, AKMA AZMIERA, et al.
Published: (2018)

Structural changes and the differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kB ligand (RANKL) in subchondral bone during the development of osteoarthritis
by: Akma Azmiera Akman,, et al.
Published: (2018)

Structural changes and the differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kB ligand (RANKL) in subchondral bone during the development of osteoarthriti
by: Akman, Akma Azmiera, et al.
Published: (2018)

Did Oligocene crustal thickening precede basin development in northern Thailand? A geochronological reassessment of Doi Inthanon and Doi Suthep
by: Gardiner, Nicholas, et al.
Published: (2016)

Degree of preoperative subchondral bone edema is not associated with pain and graft outcomes after matrix-induced autologous chondrocyte implantation
by: Ebert, J., et al.
Published: (2014)

Pediatric auricular chondrocytes gene expression analysis in monolayer culture and engineered elastic cartilage
by: Idrus, Ruszymah, et al.
Published: (2007)

Tissue engineered cartilage with different human chondrocyte sources: articular, auricular and nasal septum
by: Idrus, Ruszymah, et al.
Published: (2005)

Cartilage cell and tissue based therapy for focal defect and traumatic osteoarthritis of the articular cartilage in the knee joint
by: BHI, Ruzymah, et al.
Published: (2009)

The crosstalk between mesenchymal stem cells and damaged cartilage in osteoarthritis
by: Al-Graittee, Satar Jabbar Rahi, et al.
Published: (2020)

Electrophysiological characterisation of central sensitisation in canine spontaneous osteoarthritis
by: Hunt, James Russell, et al.
Published: (2018)

Effect of Ficus deltoidea, a medicinal plant, on cartilage protection in cartilage explant and postmenopausal rat models of osteoarthritis
by: Che Ahmad Tantowi, N., et al.
Published: (2016)

Pausing preceding and following that in that-clauses of Obama's G-20 Summit Speech in London: read vs. spontaneous speech
by: Yonca Ozkan,, et al.
Published: (2010)

Of typology and historical precedents
by: Meor Razali, Meor Mohammad Fared
Published: (2014)

Direct Gas Thickener
by: Al Hinai, Nasser Mohammed, et al.
Published: (2019)

Identifying the potential of transcription factor Sox9 gene transfer in chondrocytes differentiation and articular cartilage formation in vitro
by: Mohamad Sukri, Norhamiza, et al.
Published: (2015)

Identifying the potential of Qur’anic recitation on the proliferation of chondrocytes derived from rabbit articular cartilage: work in progress
by: Hashim, Rosyafirah, et al.
Published: (2018)

Identifying the potential of qur’anic recitation on the proliferation of chondrocytes derived from rabbit articular cartilage: work in progress
by: Hashim, Rosyafirah, et al.
Published: (2016)

Chondrocytes-induced SOX5/6/9 and TERT genes for articular cartilage tissue engineering: hype or hope?
by: Md Ali @ Tahir, Aisyah Hanani, et al.
Published: (2017)

Strides towards the realization of cure for cartilage defects and osteoarthritis: the limitation and regulatory challenges
by: Ude Chinedu Cletus,, et al.
Published: (2018)

Articular cartilage restoration in load-bearing osteochondral defects by implantation of autologous chondrocyte-fibrin constructs: an experimental study in sheep
by: Sha'ban, Munirah, et al.
Published: (2007)

Which precedes? competition or cooperation?
by: Shamsudin, Norazidah, et al.
Published: (2010)

The effects of various growth factors on the proliferation of human nasal septum chondrocytes and reconstruction of human cartilage via tissue engineering technology
by: Chua, Kien Hui, et al.
Published: (2004)

Effects of resveratrol, piceatannol and quercetin in an equine cartilage explant model for potential use in treating osteoarthritis
by: Islam, Purba
Published: (2019)