Mathematical verification of summary formula in retinal vessel diameter measurement

our previous study found the retinal vessel diameter measurement using summary formula has no significant difference for the multiple retinal images of the same person, while the individual vessel measures show the significant difference. It was speculated that the revised formula summariz...

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Main Authors: Hao, Hao, Kumar, Dinesh Kant, Aliahmad, Behzad, Che Azemin, Mohd Zulfaezal, Kawasaki, Ryo
Format: Proceeding Paper
Language:English
Published: 2013
Subjects:
Online Access:http://irep.iium.edu.my/36995/
http://irep.iium.edu.my/36995/1/HaoBRC2013_MathsVerification.pdf
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author Hao, Hao
Kumar, Dinesh Kant
Aliahmad, Behzad
Che Azemin, Mohd Zulfaezal
Kawasaki, Ryo
author_facet Hao, Hao
Kumar, Dinesh Kant
Aliahmad, Behzad
Che Azemin, Mohd Zulfaezal
Kawasaki, Ryo
author_sort Hao, Hao
building IIUM Repository
collection Online Access
description our previous study found the retinal vessel diameter measurement using summary formula has no significant difference for the multiple retinal images of the same person, while the individual vessel measures show the significant difference. It was speculated that the revised formula summarizing the individual measures and therefore against variation. This paper uses the mathematical models to verify this speculation. The impacts of the sample size, branching coefficients, different graders and grader/systemic errors are analyzed and discussed. Our results confirmed the revised formula is robust against the variation which exists on the individual measures. However, the results also demonstrate 1) the revised formula is not able to remove the systemic errors and the variations caused by the different graders. 2) the measures summarized by the revised formula may not be suitable for monitoring the changes on the individual retinal vessels.
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format Proceeding Paper
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institution International Islamic University Malaysia
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language English
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publishDate 2013
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spelling iium-369952014-06-20T01:11:35Z http://irep.iium.edu.my/36995/ Mathematical verification of summary formula in retinal vessel diameter measurement Hao, Hao Kumar, Dinesh Kant Aliahmad, Behzad Che Azemin, Mohd Zulfaezal Kawasaki, Ryo RE Ophthalmology TA164 Bioengineering our previous study found the retinal vessel diameter measurement using summary formula has no significant difference for the multiple retinal images of the same person, while the individual vessel measures show the significant difference. It was speculated that the revised formula summarizing the individual measures and therefore against variation. This paper uses the mathematical models to verify this speculation. The impacts of the sample size, branching coefficients, different graders and grader/systemic errors are analyzed and discussed. Our results confirmed the revised formula is robust against the variation which exists on the individual measures. However, the results also demonstrate 1) the revised formula is not able to remove the systemic errors and the variations caused by the different graders. 2) the measures summarized by the revised formula may not be suitable for monitoring the changes on the individual retinal vessels. 2013 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/36995/1/HaoBRC2013_MathsVerification.pdf Hao, Hao and Kumar, Dinesh Kant and Aliahmad, Behzad and Che Azemin, Mohd Zulfaezal and Kawasaki, Ryo (2013) Mathematical verification of summary formula in retinal vessel diameter measurement. In: Biosignals and Biorobotics Conference (BRC), 2013 ISSNIP , 18-20 Feb. 2013 , Rio de Janerio . http://dx.doi.org/10.1109/BRC.2013.6487528 doi:10.1109/BRC.2013.6487528
spellingShingle RE Ophthalmology
TA164 Bioengineering
Hao, Hao
Kumar, Dinesh Kant
Aliahmad, Behzad
Che Azemin, Mohd Zulfaezal
Kawasaki, Ryo
Mathematical verification of summary formula in retinal vessel diameter measurement
title Mathematical verification of summary formula in retinal vessel diameter measurement
title_full Mathematical verification of summary formula in retinal vessel diameter measurement
title_fullStr Mathematical verification of summary formula in retinal vessel diameter measurement
title_full_unstemmed Mathematical verification of summary formula in retinal vessel diameter measurement
title_short Mathematical verification of summary formula in retinal vessel diameter measurement
title_sort mathematical verification of summary formula in retinal vessel diameter measurement
topic RE Ophthalmology
TA164 Bioengineering
url http://irep.iium.edu.my/36995/
http://irep.iium.edu.my/36995/
http://irep.iium.edu.my/36995/
http://irep.iium.edu.my/36995/1/HaoBRC2013_MathsVerification.pdf