Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
Introduction: Total femur endoprosthesis is an alternative reconstruction option following resection for massive malignant bone tumour with intramedullary extension or skip lesions. Methodology: We reviewed cases with primary bone tumours underwent total femur resection and replacement with megapros...
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| Format: | Proceeding Paper |
| Language: | English English |
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2014
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| Online Access: | http://irep.iium.edu.my/36337/ http://irep.iium.edu.my/36337/1/TOTAL_FEMUR_%28APMSTS_2014%29.pdf http://irep.iium.edu.my/36337/2/APMSTS_2014_-_PROGRAMME_%26_ABSTRACT_BOOK_-_Paper_Presentations.pdf |
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| author | Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman |
| author_facet | Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman |
| author_sort | Wan Ismail, Wan Mohd Faisham |
| building | IIUM Repository |
| collection | Online Access |
| description | Introduction: Total femur endoprosthesis is an alternative reconstruction option following resection for massive malignant bone tumour with intramedullary extension or skip lesions. Methodology: We reviewed cases with primary bone tumours underwent total femur resection and replacement with megaprosthesis at our centre for the past 15 years. Results: Nine patients were included in our review. Mean age of patients was 21.3 years (range 12 to 35 years old). Seven had osteosarcoma of the femur and two were results of salvage procedure for implant loosening following distal femoral replacement. Another patient underwent surgery for revision of total femur allograft. Free oncologic margins were achieved in all patients. Four patients required vascularised latissimus dorsi free flaps cover for reconstruction of soft tissue defects. The average follow-up was 137 months, ranging from 24 to 180 months. Seven patients were still alive on their last follow up. Six of them being disease free and one survived with presence of pulmonary and contralateral femur metastases. Two patients were complicated with infections, two had stiff knee joint, and one case of peroneal nerve palsy. Excellent or good functional outcomes obtained in all patients on their last follow up in accordance to Musculoskeletal Tumor Society (MSTS) Scoring System. Conclusion: Modular endoprosthetic replacement is a good reconstruction option in selected cases. It provides early stability and good functional outcomes. However, it is a technically demanding procedure. |
| first_indexed | 2025-11-14T15:45:55Z |
| format | Proceeding Paper |
| id | iium-36337 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T15:45:55Z |
| publishDate | 2014 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-363372018-06-20T01:00:46Z http://irep.iium.edu.my/36337/ Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman RB Pathology RC254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Introduction: Total femur endoprosthesis is an alternative reconstruction option following resection for massive malignant bone tumour with intramedullary extension or skip lesions. Methodology: We reviewed cases with primary bone tumours underwent total femur resection and replacement with megaprosthesis at our centre for the past 15 years. Results: Nine patients were included in our review. Mean age of patients was 21.3 years (range 12 to 35 years old). Seven had osteosarcoma of the femur and two were results of salvage procedure for implant loosening following distal femoral replacement. Another patient underwent surgery for revision of total femur allograft. Free oncologic margins were achieved in all patients. Four patients required vascularised latissimus dorsi free flaps cover for reconstruction of soft tissue defects. The average follow-up was 137 months, ranging from 24 to 180 months. Seven patients were still alive on their last follow up. Six of them being disease free and one survived with presence of pulmonary and contralateral femur metastases. Two patients were complicated with infections, two had stiff knee joint, and one case of peroneal nerve palsy. Excellent or good functional outcomes obtained in all patients on their last follow up in accordance to Musculoskeletal Tumor Society (MSTS) Scoring System. Conclusion: Modular endoprosthetic replacement is a good reconstruction option in selected cases. It provides early stability and good functional outcomes. However, it is a technically demanding procedure. 2014-04 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/36337/1/TOTAL_FEMUR_%28APMSTS_2014%29.pdf application/pdf en http://irep.iium.edu.my/36337/2/APMSTS_2014_-_PROGRAMME_%26_ABSTRACT_BOOK_-_Paper_Presentations.pdf Wan Ismail, Wan Mohd Faisham and Sharifudin, Mohd Ariff and Wan , Zulmi and Halim, Ahmad Sukari and Mat Zin, Nor Azman and Wan Sulaiman, Wan Azman (2014) Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours. In: 10th Annual Asia Pacific Musculoskeletal Tumour Society (APMSTS) Scientific Meeting, 9-11 Apr 2014, Grand Hyatt Melbourne Australia. http://apmsts2014.aoa.org.au/program/4568385151 |
| spellingShingle | RB Pathology RC254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours |
| title | Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours |
| title_full | Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours |
| title_fullStr | Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours |
| title_full_unstemmed | Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours |
| title_short | Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours |
| title_sort | outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours |
| topic | RB Pathology RC254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics |
| url | http://irep.iium.edu.my/36337/ http://irep.iium.edu.my/36337/ http://irep.iium.edu.my/36337/1/TOTAL_FEMUR_%28APMSTS_2014%29.pdf http://irep.iium.edu.my/36337/2/APMSTS_2014_-_PROGRAMME_%26_ABSTRACT_BOOK_-_Paper_Presentations.pdf |