Fabrication and optimization of gastro retentive drug delivery system with HPMC and polyethylene oxide (PEO) matrix

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Fabrication and optimization of gastro retentive drug delivery system with HPMC and polyethylene oxide (PEO) matrix

Gastro retentive tablets of metformin HCl were prepared based on polymer swelling and gas formation. Combination of HPMC and polyethylene oxide was used as both matrix forming agent and swelling agent, while sodium bicarbonate as gas forming agent. Fabricated tablets were optimized by response surfa...

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Bibliographic Details
Main Authors:	Senjoti, Faria Gias, Jaffri, Juliana Md., Mandal, Uttam Kumar
Format:	Proceeding Paper
Language:	English
Published:	2014
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/36315/ http://irep.iium.edu.my/36315/1/Published_paper.pdf

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