Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum
The genus Calophyllum which belongs to Guttderae family is known as ‘bintangor’ by Malay local folks. Previous phytochemicals studies on several Calophyllum species successfully isolated group of pyranocoumarins. In this study, a phytochemical analysis of C. symingtonianum M. R. Hend & Wyatt-Sm....
| Main Authors: | , , |
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| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/36159/ http://irep.iium.edu.my/36159/1/Binder1.pdf |
| _version_ | 1848781172835876864 |
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| author | Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher |
| author_facet | Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher |
| author_sort | Aminudin, Nurul Iman |
| building | IIUM Repository |
| collection | Online Access |
| description | The genus Calophyllum which belongs to Guttderae family is known as ‘bintangor’ by Malay local folks. Previous phytochemicals studies on several Calophyllum species successfully isolated group of pyranocoumarins. In this study, a phytochemical analysis of C. symingtonianum M. R. Hend & Wyatt-Sm. was conducted involving stem barks, leaves and heartwood. Cold extraction method was employed by using dichloromethane and methanol to give the respective crude extracts. Two pyranocoumarins were successfully isolated from stem bark dichloromethane crude extract identified as inophyllum D and isocordato-oblongic acid. Screening on their antibacterial activities were evaluated against B. subtilis, S. aureus, P. aeruginosa, P. putida and E. coli by using disc diffusion (DD), minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) methods. The MBC values showed only the methanol stem bark crude extract inhibited P. aeruginosa and E. coli growth each at 225 ug/mI. The methanol heartwood crude extract moderately inhibited the growth of S. aureus, P. aeruginosa and P. putida each at 450 ug/mL. |
| first_indexed | 2025-11-14T15:45:21Z |
| format | Proceeding Paper |
| id | iium-36159 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:45:21Z |
| publishDate | 2014 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-361592018-06-20T06:41:43Z http://irep.iium.edu.my/36159/ Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher RS Pharmacy and materia medica The genus Calophyllum which belongs to Guttderae family is known as ‘bintangor’ by Malay local folks. Previous phytochemicals studies on several Calophyllum species successfully isolated group of pyranocoumarins. In this study, a phytochemical analysis of C. symingtonianum M. R. Hend & Wyatt-Sm. was conducted involving stem barks, leaves and heartwood. Cold extraction method was employed by using dichloromethane and methanol to give the respective crude extracts. Two pyranocoumarins were successfully isolated from stem bark dichloromethane crude extract identified as inophyllum D and isocordato-oblongic acid. Screening on their antibacterial activities were evaluated against B. subtilis, S. aureus, P. aeruginosa, P. putida and E. coli by using disc diffusion (DD), minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) methods. The MBC values showed only the methanol stem bark crude extract inhibited P. aeruginosa and E. coli growth each at 225 ug/mI. The methanol heartwood crude extract moderately inhibited the growth of S. aureus, P. aeruginosa and P. putida each at 450 ug/mL. 2014-03 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/36159/1/Binder1.pdf Aminudin, Nurul Iman and Ahmad, Farediah and Bakhtiar, M. Taher (2014) Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum. In: International Conference on Natural Products 2014, 18th-19th March 2014, Palm Garden Hotel, IOI Resorts, Putrajaya, Malaysia. http://www.ukm.my/icnp2014/ |
| spellingShingle | RS Pharmacy and materia medica Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum |
| title | Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum |
| title_full | Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum |
| title_fullStr | Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum |
| title_full_unstemmed | Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum |
| title_short | Anti bacterial activity of pyranocoumarins and crude extracts of Calophyllum symingtonianum |
| title_sort | anti bacterial activity of pyranocoumarins and crude extracts of calophyllum symingtonianum |
| topic | RS Pharmacy and materia medica |
| url | http://irep.iium.edu.my/36159/ http://irep.iium.edu.my/36159/ http://irep.iium.edu.my/36159/1/Binder1.pdf |