Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi
Persicaria odorata is a common plant and well known locally as “daun kesum” that is usually used in culinary and have various medicinal properties. This study is conducted to investigate the antimicrobial activity and the chemical constituent of the most active extract. The leaves were extracted usi...
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| Format: | Article |
| Language: | English |
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Bentham Open
2013
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| Online Access: | http://irep.iium.edu.my/35015/ http://irep.iium.edu.my/35015/5/Ridzuan_paper.pdf |
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| author | Pauzi, Muhd Ridzuan Hamzah, Hairul Aini Shah, Anis Mohd Hassan, Norazian ., Roesnita K. S., Aminah |
| author_facet | Pauzi, Muhd Ridzuan Hamzah, Hairul Aini Shah, Anis Mohd Hassan, Norazian ., Roesnita K. S., Aminah |
| author_sort | Pauzi, Muhd Ridzuan |
| building | IIUM Repository |
| collection | Online Access |
| description | Persicaria odorata is a common plant and well known locally as “daun kesum” that is usually used in culinary and have various medicinal properties. This study is conducted to investigate the antimicrobial activity and the chemical constituent of the most active extract. The leaves were extracted using n-hexane, dichloromethane, methanol and water to produce the respective extracts. All extracts were tested against eight bacterial strains which include gram positive and gram negative bacteria and one fungal strain by using disc diffusion method. In this research erythromycin 15 µg, vancomycin 30 µg and gentamicin 10 µg were used as antibacterial standard whereas miconazole 50 µg were used as antifungal. The antimicrobial activity of the active extract is evaluated quantitatively by using broth microdilution assay. Gas Chromatography-Mass (GCMS) Spectroscopy analysis was used to analyze the chemical constituent of the most active extract. n-Hexane extract was found to be the most active extract which was active against S. aureus (29.3±0.57), S. epidermidis (32.6±1.52), S. pneumonia (11.3±1.52) and S. pyogenes (15.6±1.15). However, the all extracts are inactive against fungi. The extract produced minimum inhibitory concentration (MIC) of 100µg/ml against S. aureus and 50µg/ml each against S. epidermidis, S. pneumonia and S. pyogenes. GCMS analysis has identified Decanal, Caryophyllene, Dodecanal the major constituents of n-hexane extract. The results obtained in this study showed that P. odorata leaves have high potential to be used as natural antibacterial agent against bacterial infections. |
| first_indexed | 2025-11-14T15:42:33Z |
| format | Article |
| id | iium-35015 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:42:33Z |
| publishDate | 2013 |
| publisher | Bentham Open |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-350152014-07-23T07:37:02Z http://irep.iium.edu.my/35015/ Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi Pauzi, Muhd Ridzuan Hamzah, Hairul Aini Shah, Anis Mohd Hassan, Norazian ., Roesnita K. S., Aminah QR Microbiology Persicaria odorata is a common plant and well known locally as “daun kesum” that is usually used in culinary and have various medicinal properties. This study is conducted to investigate the antimicrobial activity and the chemical constituent of the most active extract. The leaves were extracted using n-hexane, dichloromethane, methanol and water to produce the respective extracts. All extracts were tested against eight bacterial strains which include gram positive and gram negative bacteria and one fungal strain by using disc diffusion method. In this research erythromycin 15 µg, vancomycin 30 µg and gentamicin 10 µg were used as antibacterial standard whereas miconazole 50 µg were used as antifungal. The antimicrobial activity of the active extract is evaluated quantitatively by using broth microdilution assay. Gas Chromatography-Mass (GCMS) Spectroscopy analysis was used to analyze the chemical constituent of the most active extract. n-Hexane extract was found to be the most active extract which was active against S. aureus (29.3±0.57), S. epidermidis (32.6±1.52), S. pneumonia (11.3±1.52) and S. pyogenes (15.6±1.15). However, the all extracts are inactive against fungi. The extract produced minimum inhibitory concentration (MIC) of 100µg/ml against S. aureus and 50µg/ml each against S. epidermidis, S. pneumonia and S. pyogenes. GCMS analysis has identified Decanal, Caryophyllene, Dodecanal the major constituents of n-hexane extract. The results obtained in this study showed that P. odorata leaves have high potential to be used as natural antibacterial agent against bacterial infections. Bentham Open 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/35015/5/Ridzuan_paper.pdf Pauzi, Muhd Ridzuan and Hamzah, Hairul Aini and Shah, Anis and Mohd Hassan, Norazian and ., Roesnita and K. S., Aminah (2013) Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi. The Open Conference Proceedings Journal, 4 (supp-2). pp. 71-74. ISSN 2210-2892 http://www.benthamscience.com/open/openaccess.php?toprocj/articles/V004/SS0201TOPROCJ/71TOPROCJ.htm 10.2174/2210289201304020071 |
| spellingShingle | QR Microbiology Pauzi, Muhd Ridzuan Hamzah, Hairul Aini Shah, Anis Mohd Hassan, Norazian ., Roesnita K. S., Aminah Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi |
| title | Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi |
| title_full | Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi |
| title_fullStr | Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi |
| title_full_unstemmed | Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi |
| title_short | Antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi |
| title_sort | antibacterial and antifungal properties of persicaria odorata leaf against pathogenic bacteria and fungi |
| topic | QR Microbiology |
| url | http://irep.iium.edu.my/35015/ http://irep.iium.edu.my/35015/ http://irep.iium.edu.my/35015/ http://irep.iium.edu.my/35015/5/Ridzuan_paper.pdf |