Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
Screening test by using aldosterone-renin ratio (ARR) resulted in a higher prevalence (5-15%) of primary aldosteronism than was previously expected but to date there is no such study performed in Malaysia. Objectives: The aim of the study was to determine the prevalence of high ARR (>20) and high...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Malaysian Endocrine and Metabolic Society
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/33553/ http://irep.iium.edu.my/33553/1/76-267-1-PB.pdf |
| _version_ | 1848780768711540736 |
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| author | Omar , Ahmad Marzuki Abd Rahim, Firdaus Sukor, Norlela Shahar, Mohammad Arif Kamaruddin, Nor Azmi |
| author_facet | Omar , Ahmad Marzuki Abd Rahim, Firdaus Sukor, Norlela Shahar, Mohammad Arif Kamaruddin, Nor Azmi |
| author_sort | Omar , Ahmad Marzuki |
| building | IIUM Repository |
| collection | Online Access |
| description | Screening test by using aldosterone-renin ratio (ARR) resulted in a higher prevalence (5-15%) of primary aldosteronism than was previously expected but to date there is no such study performed in Malaysia. Objectives: The aim of the study was to determine the prevalence of high ARR (>20) and high plasma aldosterone concentration (PAC) (>150 pg/mL) in hypertensive subjects attending a primary care clinic. Methods: This was a cross-sectional study involving 220 essential hypertension subjects from a primary care clinic in Kuala Lumpur. Bloods for aldosterone, renin and renal profile were taken as specified in previously published protocols. Results: The prevalence of positive test for PA was 7.3%. When either ARR>20 or PAC >150 pg/mL were used, 15.0% and 17.7% of subjects fulfilled the criteria, respectively. Conclusions: The prevalence of hypertensive subjects with high ARR (>20) and PAC (>150 pg/mL) was 7.3%, justifying the need to investigate this group of subjects for PA. |
| first_indexed | 2025-11-14T15:38:55Z |
| format | Article |
| id | iium-33553 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:38:55Z |
| publishDate | 2013 |
| publisher | Malaysian Endocrine and Metabolic Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-335532014-07-22T04:23:49Z http://irep.iium.edu.my/33553/ Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic Omar , Ahmad Marzuki Abd Rahim, Firdaus Sukor, Norlela Shahar, Mohammad Arif Kamaruddin, Nor Azmi R Medicine (General) RC Internal medicine Screening test by using aldosterone-renin ratio (ARR) resulted in a higher prevalence (5-15%) of primary aldosteronism than was previously expected but to date there is no such study performed in Malaysia. Objectives: The aim of the study was to determine the prevalence of high ARR (>20) and high plasma aldosterone concentration (PAC) (>150 pg/mL) in hypertensive subjects attending a primary care clinic. Methods: This was a cross-sectional study involving 220 essential hypertension subjects from a primary care clinic in Kuala Lumpur. Bloods for aldosterone, renin and renal profile were taken as specified in previously published protocols. Results: The prevalence of positive test for PA was 7.3%. When either ARR>20 or PAC >150 pg/mL were used, 15.0% and 17.7% of subjects fulfilled the criteria, respectively. Conclusions: The prevalence of hypertensive subjects with high ARR (>20) and PAC (>150 pg/mL) was 7.3%, justifying the need to investigate this group of subjects for PA. Malaysian Endocrine and Metabolic Society 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/33553/1/76-267-1-PB.pdf Omar , Ahmad Marzuki and Abd Rahim, Firdaus and Sukor, Norlela and Shahar, Mohammad Arif and Kamaruddin, Nor Azmi (2013) Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic. Journal of Endocrinology and Metabolism, 3 (1). pp. 40-47. ISSN 2229-9572 http://www.jmems.org/index.php/jmems/article/viewFile/76/60 |
| spellingShingle | R Medicine (General) RC Internal medicine Omar , Ahmad Marzuki Abd Rahim, Firdaus Sukor, Norlela Shahar, Mohammad Arif Kamaruddin, Nor Azmi Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic |
| title | Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic |
| title_full | Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic |
| title_fullStr | Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic |
| title_full_unstemmed | Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic |
| title_short | Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic |
| title_sort | prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic |
| topic | R Medicine (General) RC Internal medicine |
| url | http://irep.iium.edu.my/33553/ http://irep.iium.edu.my/33553/ http://irep.iium.edu.my/33553/1/76-267-1-PB.pdf |