A review on the formulation and analysis of anti-diabetic agent: Gliclazide

Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM) and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to ha...

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Main Authors: Helal Uddin, A.B.M., Alaama, Mohammed, Abdualkader, Abdualrahman Mohammed, Awang, Mohamed, Ahmed, Qamar Uddin, Abbas, Syed Atif
Format: Article
Language:English
Published: Trans Tech Publications, Switzerland 2013
Subjects:
Online Access:http://irep.iium.edu.my/32319/
http://irep.iium.edu.my/32319/1/Glaclizide-paper.pdf
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author Helal Uddin, A.B.M.
Alaama, Mohammed
Abdualkader, Abdualrahman Mohammed
Awang, Mohamed
Ahmed, Qamar Uddin
Abbas, Syed Atif
author_facet Helal Uddin, A.B.M.
Alaama, Mohammed
Abdualkader, Abdualrahman Mohammed
Awang, Mohamed
Ahmed, Qamar Uddin
Abbas, Syed Atif
author_sort Helal Uddin, A.B.M.
building IIUM Repository
collection Online Access
description Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM) and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to have many other important effects, such as: suppression of platelet functions, antithrombotic actions, decreased the production of tumour necrosis factor (TNF) á by endothelial cells and other effects. The unique activities of gliclazide has open a new avenue for the drug development research. This work is aimed to provide comprehensive information about gliclazide and its current research activities.
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institution International Islamic University Malaysia
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publishDate 2013
publisher Trans Tech Publications, Switzerland
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spelling iium-323192022-11-07T03:33:21Z http://irep.iium.edu.my/32319/ A review on the formulation and analysis of anti-diabetic agent: Gliclazide Helal Uddin, A.B.M. Alaama, Mohammed Abdualkader, Abdualrahman Mohammed Awang, Mohamed Ahmed, Qamar Uddin Abbas, Syed Atif QD Chemistry RS Pharmacy and materia medica Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM) and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to have many other important effects, such as: suppression of platelet functions, antithrombotic actions, decreased the production of tumour necrosis factor (TNF) á by endothelial cells and other effects. The unique activities of gliclazide has open a new avenue for the drug development research. This work is aimed to provide comprehensive information about gliclazide and its current research activities. Trans Tech Publications, Switzerland 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/32319/1/Glaclizide-paper.pdf Helal Uddin, A.B.M. and Alaama, Mohammed and Abdualkader, Abdualrahman Mohammed and Awang, Mohamed and Ahmed, Qamar Uddin and Abbas, Syed Atif (2013) A review on the formulation and analysis of anti-diabetic agent: Gliclazide. Advanced Materials Research, 810. pp. 159-172. ISSN 1022-6680 http://www.scientific.net/AMR.810.159 10.4028/www.scientific.net/AMR.810.159
spellingShingle QD Chemistry
RS Pharmacy and materia medica
Helal Uddin, A.B.M.
Alaama, Mohammed
Abdualkader, Abdualrahman Mohammed
Awang, Mohamed
Ahmed, Qamar Uddin
Abbas, Syed Atif
A review on the formulation and analysis of anti-diabetic agent: Gliclazide
title A review on the formulation and analysis of anti-diabetic agent: Gliclazide
title_full A review on the formulation and analysis of anti-diabetic agent: Gliclazide
title_fullStr A review on the formulation and analysis of anti-diabetic agent: Gliclazide
title_full_unstemmed A review on the formulation and analysis of anti-diabetic agent: Gliclazide
title_short A review on the formulation and analysis of anti-diabetic agent: Gliclazide
title_sort review on the formulation and analysis of anti-diabetic agent: gliclazide
topic QD Chemistry
RS Pharmacy and materia medica
url http://irep.iium.edu.my/32319/
http://irep.iium.edu.my/32319/
http://irep.iium.edu.my/32319/
http://irep.iium.edu.my/32319/1/Glaclizide-paper.pdf