A central bioactive region of LTBP-2 stimulates the expression of TGF-β1 in fibroblasts via akt and p38 signalling pathways

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A central bioactive region of LTBP-2 stimulates the expression of TGF-β1 in fibroblasts via akt and p38 signalling pathways

Latent transforming growth factor-β-1 binding protein-2 (LTBP-2) belongs to the LTBP-fibrillin superfamily of extracellular proteins. Unlike other LTBPs, LTBP-2 does not covalently bind transforming growth factor-β1 (TGF-β1) but appears to be implicated in the regulation of TGF-β1 bioactivity, altho...

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Bibliographic Details
Main Authors:	Sideek, Mohamed Arshad, Smith, Joshua J., Menz, Clementine, Adams, Julian R. J., Cowin, Allison J., Gibson, Mark A.
Format:	Article
Language:	English English
Published:	Multidisciplinary Digital Publishing Institute (MDPI) 2017
Subjects:	QD Chemistry R Medicine (General) RA0421 Public health. Hygiene. Preventive Medicine
Online Access:	http://irep.iium.edu.my/31820/ http://irep.iium.edu.my/31820/1/31820_A%20Central%20Bioactive%20Region%20of%20LTBP-2%20Stimulates.pdf http://irep.iium.edu.my/31820/2/31820_A%20Central%20Bioactive%20Region%20of%20LTBP-2%20Stimulates_scopus.pdf

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