The influence of premenopausal hysterectomy on bone mineral density

Objective: To investigate whether premenopausal hysterectomy has an effect on bone mass in women in their fifties . Methods: This cross-sectional study was performed on 25 healthy women who had premenopausal hysterectomy before the age of 45 and at least 2 years before the study with 40 healthy...

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Main Authors: Abdulwahab, Dalia F, Al- Baldawy, Reyad, Chabek, Mohammed, Awang, Mokhtar, Abd. Wahab, Noraziana, Al-Kubaisi, Muna Khaleel Dheyab
Format: Proceeding Paper
Language:English
English
Published: 2012
Subjects:
Online Access:http://irep.iium.edu.my/31336/
http://irep.iium.edu.my/31336/1/drdalia_f_correctedPosterPresentations.RCOG.pdf
http://irep.iium.edu.my/31336/4/the_influence_of_premenopausal.pdf
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author Abdulwahab, Dalia F
Al- Baldawy, Reyad
Chabek, Mohammed
Awang, Mokhtar
Abd. Wahab, Noraziana
Al-Kubaisi, Muna Khaleel Dheyab
author_facet Abdulwahab, Dalia F
Al- Baldawy, Reyad
Chabek, Mohammed
Awang, Mokhtar
Abd. Wahab, Noraziana
Al-Kubaisi, Muna Khaleel Dheyab
author_sort Abdulwahab, Dalia F
building IIUM Repository
collection Online Access
description Objective: To investigate whether premenopausal hysterectomy has an effect on bone mass in women in their fifties . Methods: This cross-sectional study was performed on 25 healthy women who had premenopausal hysterectomy before the age of 45 and at least 2 years before the study with 40 healthy natural postmenopausal women 45–60 years old. Evaluation of the menopausal state was done by measuring serum follicular stimulating hormone and serum estradiol. Bone mineral density of the left proximal femur was determined by dual energy X-ray absorptiometry in six regions (femoral neck, greater trochanter, interochantric, ward‘s triangle, shaft, total hip region). Evaluation of bone remodeling done by measuring serum alkaline phosphotase. The result of both groups were compared. Results: The study showed slight increment of BMD among cases with hysterectomy than the control group by an amount ranging between 1.9% in the femoral shaft to 4.8% in the greater trochanter and ward‘s triangle. These differences were not statistically significant and even when they were exceptionally significant as the case with BMD of the femoral neck and intertrochantric area they were too small in magnitude to be of clinical relevance. Conclusion: Hysterectomy had no impact on bone parameters even after adjusting for the duration of menopause.
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format Proceeding Paper
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institution International Islamic University Malaysia
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language English
English
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publishDate 2012
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spelling iium-313362013-11-06T07:06:59Z http://irep.iium.edu.my/31336/ The influence of premenopausal hysterectomy on bone mineral density Abdulwahab, Dalia F Al- Baldawy, Reyad Chabek, Mohammed Awang, Mokhtar Abd. Wahab, Noraziana Al-Kubaisi, Muna Khaleel Dheyab RG Gynecology and obstetrics Objective: To investigate whether premenopausal hysterectomy has an effect on bone mass in women in their fifties . Methods: This cross-sectional study was performed on 25 healthy women who had premenopausal hysterectomy before the age of 45 and at least 2 years before the study with 40 healthy natural postmenopausal women 45–60 years old. Evaluation of the menopausal state was done by measuring serum follicular stimulating hormone and serum estradiol. Bone mineral density of the left proximal femur was determined by dual energy X-ray absorptiometry in six regions (femoral neck, greater trochanter, interochantric, ward‘s triangle, shaft, total hip region). Evaluation of bone remodeling done by measuring serum alkaline phosphotase. The result of both groups were compared. Results: The study showed slight increment of BMD among cases with hysterectomy than the control group by an amount ranging between 1.9% in the femoral shaft to 4.8% in the greater trochanter and ward‘s triangle. These differences were not statistically significant and even when they were exceptionally significant as the case with BMD of the femoral neck and intertrochantric area they were too small in magnitude to be of clinical relevance. Conclusion: Hysterectomy had no impact on bone parameters even after adjusting for the duration of menopause. 2012 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/31336/1/drdalia_f_correctedPosterPresentations.RCOG.pdf application/pdf en http://irep.iium.edu.my/31336/4/the_influence_of_premenopausal.pdf Abdulwahab, Dalia F and Al- Baldawy, Reyad and Chabek, Mohammed and Awang, Mokhtar and Abd. Wahab, Noraziana and Al-Kubaisi, Muna Khaleel Dheyab (2012) The influence of premenopausal hysterectomy on bone mineral density. In: 10th International Scientific Congress of the Royal College of Obstetricians and Gynaecologists, 5-8 Jun 2012, Kuching, Sarawak. (Unpublished)
spellingShingle RG Gynecology and obstetrics
Abdulwahab, Dalia F
Al- Baldawy, Reyad
Chabek, Mohammed
Awang, Mokhtar
Abd. Wahab, Noraziana
Al-Kubaisi, Muna Khaleel Dheyab
The influence of premenopausal hysterectomy on bone mineral density
title The influence of premenopausal hysterectomy on bone mineral density
title_full The influence of premenopausal hysterectomy on bone mineral density
title_fullStr The influence of premenopausal hysterectomy on bone mineral density
title_full_unstemmed The influence of premenopausal hysterectomy on bone mineral density
title_short The influence of premenopausal hysterectomy on bone mineral density
title_sort influence of premenopausal hysterectomy on bone mineral density
topic RG Gynecology and obstetrics
url http://irep.iium.edu.my/31336/
http://irep.iium.edu.my/31336/1/drdalia_f_correctedPosterPresentations.RCOG.pdf
http://irep.iium.edu.my/31336/4/the_influence_of_premenopausal.pdf