Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia

We retrospectively reviewed 70 cases of adult pulmonary melioidosis in Pahang from January 2000 to June 2003. There was a strong association with diabetes mellitus, 82.8% of them were diabetic. Fever was the commonest presentation (96%) followed by cough (75%). 11.8% of patients presented with shock...

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Main Authors: How, Soon Hin, Tee, Hoi Poh, Ab Rahman, Jamalludin, Shah, Anis, Rathor, Mohammad Yousuf
Format: Article
Language:English
Published: Faculty of Medicine, International Islamic University Malaysia 2005
Subjects:
Online Access:http://irep.iium.edu.my/29439/
http://irep.iium.edu.my/29439/1/Pulmonary_Melioidosis.pdf
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author How, Soon Hin
Tee, Hoi Poh
Ab Rahman, Jamalludin
Shah, Anis
Rathor, Mohammad Yousuf
author_facet How, Soon Hin
Tee, Hoi Poh
Ab Rahman, Jamalludin
Shah, Anis
Rathor, Mohammad Yousuf
author_sort How, Soon Hin
building IIUM Repository
collection Online Access
description We retrospectively reviewed 70 cases of adult pulmonary melioidosis in Pahang from January 2000 to June 2003. There was a strong association with diabetes mellitus, 82.8% of them were diabetic. Fever was the commonest presentation (96%) followed by cough (75%). 11.8% of patients presented with shock of whom 87.5% died within 24 hours. There was no pathognomonic feature on chest radiograph; but multi-lobar involvement was more common. In our series, B.pseudomallei was most commonly sensitive to cefoperazone-sulbactam (100%), imipenem(100%) and ceftazidime (98.6%). Nearly half (51.4%) of our patients received appropriate empirical antibiotics and the mortality was 71%.
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institution International Islamic University Malaysia
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language English
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publishDate 2005
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spelling iium-294392016-03-10T06:50:04Z http://irep.iium.edu.my/29439/ Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia How, Soon Hin Tee, Hoi Poh Ab Rahman, Jamalludin Shah, Anis Rathor, Mohammad Yousuf R Medicine (General) We retrospectively reviewed 70 cases of adult pulmonary melioidosis in Pahang from January 2000 to June 2003. There was a strong association with diabetes mellitus, 82.8% of them were diabetic. Fever was the commonest presentation (96%) followed by cough (75%). 11.8% of patients presented with shock of whom 87.5% died within 24 hours. There was no pathognomonic feature on chest radiograph; but multi-lobar involvement was more common. In our series, B.pseudomallei was most commonly sensitive to cefoperazone-sulbactam (100%), imipenem(100%) and ceftazidime (98.6%). Nearly half (51.4%) of our patients received appropriate empirical antibiotics and the mortality was 71%. Faculty of Medicine, International Islamic University Malaysia 2005-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29439/1/Pulmonary_Melioidosis.pdf How, Soon Hin and Tee, Hoi Poh and Ab Rahman, Jamalludin and Shah, Anis and Rathor, Mohammad Yousuf (2005) Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia. International Medical Journal Malaysia, 4 (1). (1-7). ISSN 1823-4631 http://www.eimjm.com/Vol4-No1/Vol4-No1-B16.htm
spellingShingle R Medicine (General)
How, Soon Hin
Tee, Hoi Poh
Ab Rahman, Jamalludin
Shah, Anis
Rathor, Mohammad Yousuf
Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia
title Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia
title_full Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia
title_fullStr Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia
title_full_unstemmed Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia
title_short Pulmonary melioidosis: a review of 70 cases from Pahang, Malaysia
title_sort pulmonary melioidosis: a review of 70 cases from pahang, malaysia
topic R Medicine (General)
url http://irep.iium.edu.my/29439/
http://irep.iium.edu.my/29439/
http://irep.iium.edu.my/29439/1/Pulmonary_Melioidosis.pdf