Pediatric melioidosis in Pahang, Malaysia
Melioidosis is much less common in children than in adults. This study investigated the incidence, demographic characteristics, presenting symptoms and outcome of pediatric melioidosis in Pahang, Malaysia. This retrospective study included patients < or =18 years old with positive body fluid cult...
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| Format: | Article |
| Language: | English |
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Elsevier Inc.
2005
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| Online Access: | http://irep.iium.edu.my/29432/ http://irep.iium.edu.my/29432/1/Pediatric_melioidosis_in_Pahang.pdf |
| _version_ | 1848780122439548928 |
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| author | How, Soon Hin Ng, Kok Heng Yeo, Heng Bon Tee, Hoi-Poh Shah, Anis |
| author_facet | How, Soon Hin Ng, Kok Heng Yeo, Heng Bon Tee, Hoi-Poh Shah, Anis |
| author_sort | How, Soon Hin |
| building | IIUM Repository |
| collection | Online Access |
| description | Melioidosis is much less common in children than in adults. This study investigated the incidence, demographic characteristics, presenting symptoms and outcome of pediatric melioidosis in Pahang, Malaysia. This retrospective study included patients < or =18 years old with positive body fluid cultures for Burkholderia pseudomallei from January 2000 to June 2003. Data on culture results were obtained from 2 referral hospitals. The incidence of pediatric melioidosis was 0.68/100,000 population per year. Of the 13 patients identified during the study period, 10 were male; 9 were Malays, 2 were Indians and 2 were aborigines. The mean age of these patients was 9.5 +/- 5.4 years. None of the patients had a previous history of confirmed melioidosis or predisposing factors for infection. Localized melioidosis was the most common presentation (46.2%) followed by melioidosis with septic shock (38.4%). Among patients with localized melioidosis, head and neck involvement (83.3%) was the most common presentation (2 patients with cervical abscesses, 1 with submandibular abscesses and 2 with acute suppurative parotitis) and another patient had right axillary abscess. All of the patients with septic shock had pneumonia and 2 of them had multi-organ involvement. The mortality among patients with septic shock was 80% and death occurred within 24 h of admission in all cases. In contrast, no complications or death occurred among patients with localized melioidosis. Melioidosis with septic shock is less common than localized melioidosis in pediatric patients, but is associated with very high mortality. |
| first_indexed | 2025-11-14T15:28:39Z |
| format | Article |
| id | iium-29432 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:28:39Z |
| publishDate | 2005 |
| publisher | Elsevier Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-294322013-04-17T07:08:38Z http://irep.iium.edu.my/29432/ Pediatric melioidosis in Pahang, Malaysia How, Soon Hin Ng, Kok Heng Yeo, Heng Bon Tee, Hoi-Poh Shah, Anis R Medicine (General) RJ101 Child Heatlh. Child health services. Preventive health services for children Melioidosis is much less common in children than in adults. This study investigated the incidence, demographic characteristics, presenting symptoms and outcome of pediatric melioidosis in Pahang, Malaysia. This retrospective study included patients < or =18 years old with positive body fluid cultures for Burkholderia pseudomallei from January 2000 to June 2003. Data on culture results were obtained from 2 referral hospitals. The incidence of pediatric melioidosis was 0.68/100,000 population per year. Of the 13 patients identified during the study period, 10 were male; 9 were Malays, 2 were Indians and 2 were aborigines. The mean age of these patients was 9.5 +/- 5.4 years. None of the patients had a previous history of confirmed melioidosis or predisposing factors for infection. Localized melioidosis was the most common presentation (46.2%) followed by melioidosis with septic shock (38.4%). Among patients with localized melioidosis, head and neck involvement (83.3%) was the most common presentation (2 patients with cervical abscesses, 1 with submandibular abscesses and 2 with acute suppurative parotitis) and another patient had right axillary abscess. All of the patients with septic shock had pneumonia and 2 of them had multi-organ involvement. The mortality among patients with septic shock was 80% and death occurred within 24 h of admission in all cases. In contrast, no complications or death occurred among patients with localized melioidosis. Melioidosis with septic shock is less common than localized melioidosis in pediatric patients, but is associated with very high mortality. Elsevier Inc. 2005-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29432/1/Pediatric_melioidosis_in_Pahang.pdf How, Soon Hin and Ng, Kok Heng and Yeo, Heng Bon and Tee, Hoi-Poh and Shah, Anis (2005) Pediatric melioidosis in Pahang, Malaysia. Journal of Microbiology, Immunology and Infection, 38 (5). pp. 314-319. ISSN 1684-1182 http://www.ejmii.com/issue_abstract.php?code=PDT4b0f3a51a3aa4 |
| spellingShingle | R Medicine (General) RJ101 Child Heatlh. Child health services. Preventive health services for children How, Soon Hin Ng, Kok Heng Yeo, Heng Bon Tee, Hoi-Poh Shah, Anis Pediatric melioidosis in Pahang, Malaysia |
| title | Pediatric melioidosis in Pahang, Malaysia |
| title_full | Pediatric melioidosis in Pahang, Malaysia |
| title_fullStr | Pediatric melioidosis in Pahang, Malaysia |
| title_full_unstemmed | Pediatric melioidosis in Pahang, Malaysia |
| title_short | Pediatric melioidosis in Pahang, Malaysia |
| title_sort | pediatric melioidosis in pahang, malaysia |
| topic | R Medicine (General) RJ101 Child Heatlh. Child health services. Preventive health services for children |
| url | http://irep.iium.edu.my/29432/ http://irep.iium.edu.my/29432/ http://irep.iium.edu.my/29432/1/Pediatric_melioidosis_in_Pahang.pdf |