Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
Urate lowering therapy in this country has mainly been achieved by the use of allopurinol and probenecid. A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout. In this report, we describe the management of a patient with chronic tophace...
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| Format: | Article |
| Language: | English English |
| Published: |
Malaysian Medical Associations
2012
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/29313/ http://irep.iium.edu.my/29313/1/Use_of_Newly_Available_Febuxostat_in_a_Case_of_Chronic.pdf http://irep.iium.edu.my/29313/4/58485_Use%20of%20newly%20available%20f_scopus.pdf |
| _version_ | 1848780100789600256 |
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| author | Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah |
| author_facet | Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah |
| author_sort | Abdullah, Hilmi |
| building | IIUM Repository |
| collection | Online Access |
| description | Urate lowering therapy in this country has mainly been achieved by the use of allopurinol and probenecid. A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout. In this report, we describe the management of a patient with chronic tophaceous gout using febuxostat. The reduction in serum uric acid to target levels was rapid, and the tophi size had also reduced significantly while on therapy. There was no unwanted side effect observed during the therapy. Therefore, febuxostat would be a useful alternative drug in the treatment of hyperuricaemia in gout patients who have contraindications to allopurinol and probenecid |
| first_indexed | 2025-11-14T15:28:18Z |
| format | Article |
| id | iium-29313 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T15:28:18Z |
| publishDate | 2012 |
| publisher | Malaysian Medical Associations |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-293132017-09-28T07:18:01Z http://irep.iium.edu.my/29313/ Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah R Medicine (General) Urate lowering therapy in this country has mainly been achieved by the use of allopurinol and probenecid. A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout. In this report, we describe the management of a patient with chronic tophaceous gout using febuxostat. The reduction in serum uric acid to target levels was rapid, and the tophi size had also reduced significantly while on therapy. There was no unwanted side effect observed during the therapy. Therefore, febuxostat would be a useful alternative drug in the treatment of hyperuricaemia in gout patients who have contraindications to allopurinol and probenecid Malaysian Medical Associations 2012-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29313/1/Use_of_Newly_Available_Febuxostat_in_a_Case_of_Chronic.pdf application/pdf en http://irep.iium.edu.my/29313/4/58485_Use%20of%20newly%20available%20f_scopus.pdf Abdullah, Hilmi and Mohamad Ismail, Asmahan and Rosman, Azmillah (2012) Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid. Medical Journal of Malaysia, 67 (1). pp. 125-126. ISSN 0300-5283 http://www.myjurnal.my/public/article-view.php?id=58997 |
| spellingShingle | R Medicine (General) Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid |
| title | Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid |
| title_full | Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid |
| title_fullStr | Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid |
| title_full_unstemmed | Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid |
| title_short | Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid |
| title_sort | use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid |
| topic | R Medicine (General) |
| url | http://irep.iium.edu.my/29313/ http://irep.iium.edu.my/29313/ http://irep.iium.edu.my/29313/1/Use_of_Newly_Available_Febuxostat_in_a_Case_of_Chronic.pdf http://irep.iium.edu.my/29313/4/58485_Use%20of%20newly%20available%20f_scopus.pdf |