Malignant glioma: The involvement of loss of allelic heterozygosity and PTEN mutations in a group of Malay patients

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Malignant glioma: The involvement of loss of allelic heterozygosity and PTEN mutations in a group of Malay patients

Frequent loss of heterozygosity (LOH) and mutations of the tumor suppressor gene PTEN (phosphatase and tensin homologue deleted from chromosome 10) have been found in sporadic gliomas. The most documented regions of allelic losses include 9p21, 10q23-25 and 17p13 whereas PTEN aberrations are prefere...

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Bibliographic Details
Main Authors:	Zainuddin, Norafiza, Jaafar, Hasnan, Isa, Mohd. Nizam, Abdullah, Jafri Malin
Format:	Article
Language:	English
Published:	Faculty of Tropical Medicine, Mahidol University 2005
Subjects:	R Medicine (General) RC254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://irep.iium.edu.my/28467/ http://irep.iium.edu.my/28467/1/J_Trop_Med.pdf

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