Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)
Dilated spaces at intercellular junctions (DIS) in prickle cell layers are considered as early signs of acid-initiated damage to these esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial...
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| Format: | Article |
| Language: | English |
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Microscopy Society of Malaysia
2012
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| Online Access: | http://irep.iium.edu.my/27252/ http://irep.iium.edu.my/27252/1/Esophageal_Reflux_Disease.pdf |
| _version_ | 1848779790306246656 |
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| author | Myint, Yi Yi Tun, Ye Muhamad Amjad, Nasser Mat Hassan, Mohd Zailani Rashid, N.L |
| author_facet | Myint, Yi Yi Tun, Ye Muhamad Amjad, Nasser Mat Hassan, Mohd Zailani Rashid, N.L |
| author_sort | Myint, Yi Yi |
| building | IIUM Repository |
| collection | Online Access |
| description | Dilated spaces at intercellular junctions (DIS) in prickle cell layers are considered as early signs of acid-initiated damage to these esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore intercellular communications superficial esophageal cells in non- erosive reflux disease (NERD) patients. The study group included eight (NERD) patients and five normal controls individuals. Specimens were routinely processed for SEM observations. The nature of intercellular attachments and intercellular spaces between each individual superficial cells of the esophageal mucosa were viewed under SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings seems to support the concept of abnormal tissue resistance in the pathogenesis of NERD patients. |
| first_indexed | 2025-11-14T15:23:22Z |
| format | Article |
| id | iium-27252 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:23:22Z |
| publishDate | 2012 |
| publisher | Microscopy Society of Malaysia |
| recordtype | eprints |
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| spelling | iium-272522012-12-05T06:56:27Z http://irep.iium.edu.my/27252/ Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) Myint, Yi Yi Tun, Ye Muhamad Amjad, Nasser Mat Hassan, Mohd Zailani Rashid, N.L R Medicine (General) Dilated spaces at intercellular junctions (DIS) in prickle cell layers are considered as early signs of acid-initiated damage to these esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore intercellular communications superficial esophageal cells in non- erosive reflux disease (NERD) patients. The study group included eight (NERD) patients and five normal controls individuals. Specimens were routinely processed for SEM observations. The nature of intercellular attachments and intercellular spaces between each individual superficial cells of the esophageal mucosa were viewed under SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings seems to support the concept of abnormal tissue resistance in the pathogenesis of NERD patients. Microscopy Society of Malaysia 2012-11 Article PeerReviewed application/pdf en http://irep.iium.edu.my/27252/1/Esophageal_Reflux_Disease.pdf Myint, Yi Yi and Tun, Ye and Muhamad Amjad, Nasser and Mat Hassan, Mohd Zailani and Rashid, N.L (2012) Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM). Malaysian Journal of Microscopy, 8. pp. 139-142. ISSN 1823-7010 |
| spellingShingle | R Medicine (General) Myint, Yi Yi Tun, Ye Muhamad Amjad, Nasser Mat Hassan, Mohd Zailani Rashid, N.L Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) |
| title | Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) |
| title_full | Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) |
| title_fullStr | Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) |
| title_full_unstemmed | Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) |
| title_short | Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) |
| title_sort | esophageal surface cells in non-erosive reflux disease: a scanning electron microscopical study (sem) |
| topic | R Medicine (General) |
| url | http://irep.iium.edu.my/27252/ http://irep.iium.edu.my/27252/1/Esophageal_Reflux_Disease.pdf |