Acoustic wave based MEMS devices for biosensing applications

This paper presents a review of acoustic-wave based MEMS devices that offer a promising technology platform for the development of sensitive, portable, real-time biosensors. MEMS fabrication of acoustic wave based biosensors enables device miniaturization, power consumption reduction and integrati...

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Main Authors: Voiculescu, Ioana, Nordin, Anis Nurashikin
Format: Article
Language:English
Published: Elsevier 2012
Subjects:
Online Access:http://irep.iium.edu.my/26717/
http://irep.iium.edu.my/26717/1/saw-ioana.pdf
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author Voiculescu, Ioana
Nordin, Anis Nurashikin
author_facet Voiculescu, Ioana
Nordin, Anis Nurashikin
author_sort Voiculescu, Ioana
building IIUM Repository
collection Online Access
description This paper presents a review of acoustic-wave based MEMS devices that offer a promising technology platform for the development of sensitive, portable, real-time biosensors. MEMS fabrication of acoustic wave based biosensors enables device miniaturization, power consumption reduction and integration with electronic circuits. For biological applications, the biosensors are integrated in a microfluidic system and the sensing area is coated with a biospecific layer. When a bioanalyte interacts with the sensing layer, mass and viscosity variations of the biospecific layer can be detected by monitoring changes in the acoustic wave properties such as velocity, attenuation, resonant frequency and delay time. Few types of acoustic wave devices could be integrated in microfluidic systems without significant degradation of the quality factor. The acoustic wave based MEMS devices reported in the literature as biosensors and presented in this review are film bulk acoustic wave resonators (FBAR), surface acoustic waves (SAW) resonators and SAW delay lines. Different approaches to the realization of FBARs, SAW resonators and SAW delay lines for various biochemical applications are presented. Methods of integration of the acoustic wave MEMS devices in the microfluidic systems and functionalization strategies will be also discussed.
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spelling iium-267172012-11-29T00:07:21Z http://irep.iium.edu.my/26717/ Acoustic wave based MEMS devices for biosensing applications Voiculescu, Ioana Nordin, Anis Nurashikin T Technology (General) TK7885 Computer engineering This paper presents a review of acoustic-wave based MEMS devices that offer a promising technology platform for the development of sensitive, portable, real-time biosensors. MEMS fabrication of acoustic wave based biosensors enables device miniaturization, power consumption reduction and integration with electronic circuits. For biological applications, the biosensors are integrated in a microfluidic system and the sensing area is coated with a biospecific layer. When a bioanalyte interacts with the sensing layer, mass and viscosity variations of the biospecific layer can be detected by monitoring changes in the acoustic wave properties such as velocity, attenuation, resonant frequency and delay time. Few types of acoustic wave devices could be integrated in microfluidic systems without significant degradation of the quality factor. The acoustic wave based MEMS devices reported in the literature as biosensors and presented in this review are film bulk acoustic wave resonators (FBAR), surface acoustic waves (SAW) resonators and SAW delay lines. Different approaches to the realization of FBARs, SAW resonators and SAW delay lines for various biochemical applications are presented. Methods of integration of the acoustic wave MEMS devices in the microfluidic systems and functionalization strategies will be also discussed. Elsevier 2012 Article PeerReviewed application/pdf en http://irep.iium.edu.my/26717/1/saw-ioana.pdf Voiculescu, Ioana and Nordin, Anis Nurashikin (2012) Acoustic wave based MEMS devices for biosensing applications. Biosensors and Bioelectronics, 33. pp. 1-9. ISSN 0956-5663 http://www.sciencedirect.com/science/article/pii/S0956566311008633
spellingShingle T Technology (General)
TK7885 Computer engineering
Voiculescu, Ioana
Nordin, Anis Nurashikin
Acoustic wave based MEMS devices for biosensing applications
title Acoustic wave based MEMS devices for biosensing applications
title_full Acoustic wave based MEMS devices for biosensing applications
title_fullStr Acoustic wave based MEMS devices for biosensing applications
title_full_unstemmed Acoustic wave based MEMS devices for biosensing applications
title_short Acoustic wave based MEMS devices for biosensing applications
title_sort acoustic wave based mems devices for biosensing applications
topic T Technology (General)
TK7885 Computer engineering
url http://irep.iium.edu.my/26717/
http://irep.iium.edu.my/26717/
http://irep.iium.edu.my/26717/1/saw-ioana.pdf