High initial burst release of gentamicin formulated as PLGA microspheres implant for treating orthopaedic infection

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High initial burst release of gentamicin formulated as PLGA microspheres implant for treating orthopaedic infection

Antibiotic treatment of orthopaedic infection is complicated by systemic toxicity and the need of effective therapeutic concentration necessary to ensure optimum killing of bacteria. To overcome the problem of systemic toxicity and to achieve a high initial release followed by sustained release of a...

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Bibliographic Details
Main Authors:	Harun Ismail, Ahmad Fahmi, Doolaanea, Abd Monem, Awang, Mohamed, Mohamed, Farahidah
Format:	Article
Language:	English
Published:	Academic Sciences 2012
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/25825/ http://irep.iium.edu.my/25825/1/High_burst_release_gentamicin_formulated_as_PLGAmicrospheres.pdf

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