Biotransformation and stereoselective synthesis of pharmaceutical molecules from linoleic acid

QR Code

Biotransformation and stereoselective synthesis of pharmaceutical molecules from linoleic acid

The biotransformation of linoleic acid 1 using immobilised soybean lipoxygenase in a dimethyl sulfoxide (DMSO) containing medium followed by sodium borohydride reduction afforded 13(S)-hydroxy-octadeca-9(Z),11(E)-dienoic acid 13(S)-HODE 2 in 69% yield. After methylation, methyl 13(S)-HODE was subjec...

Full description

Bibliographic Details
Main Authors:	Omar, Muhammad Nor, Muhd Nor, Nor Nazuha, Moynihan, Humphrey, Hamilton, Richard J.
Format:	Article
Language:	English
Published:	Asian Network for Scientific Information 2007
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/24445/ http://irep.iium.edu.my/24445/1/Biotransformation_and_stereoselective_synthesis_of_pharmaceutical_molecules_from_linoleic_acid.pdf

Similar Items

Stereoselective preparations of epoxy-, fluoro- and related derivatives of ricinoleic acid and 13(S)-hydroxyoctadeca-9(Z),11(E)-dienoic acid
by: Omar, Muhammad Nor, et al.
Published: (2003)

Scaling-up the production of 13s-hydroxy-9Z,11E-octadecadienoic acid (13S-HODE) through chemoenzymatic technique
by: Omar, Muhammad Nor, et al.
Published: (2003)

Asymmetric Sharpless epoxidation of 13Shydroxy-9Z,11E-octadecadienoic acid (13S-HODE)
by: Omar, Muhammad Nor, et al.
Published: (2003)

Biotransformation of asiaticoside using Aspergillus niger and pharmaceutical properties of its transformed product
by: Omar, Muhammad Nor, et al.
Published: (2016)

Biotransformation of ω fatty acids using pseudomonas aeruginosa
by: Omar, Muhammad Nor
Published: (2012)

Biotransformation of ω-fatty acid – in search of erectile dysfunction treatments
by: Omar, Muhammad Nor, et al.
Published: (2010)

Biotransformation of ω-fatty acid from Clarias gariepinus using Psuedomonas aeruginosa
by: Omar, Muhammad Nor, et al.
Published: (2012)

Chemoenzymatic and biotransformation approaches for pharmaceutical applications
by: Omar, Muhammad Nor
Published: (2009)

Cytotoxicity activity of biotransformed ethyl p-methoxycinnamate by Aspergillus niger
by: Omar, Muhammad Nor, et al.
Published: (2016)

Wound healing properties of biotransformed asiaticoside by aspergillus niger
by: Omar, Muhammad Nor, et al.
Published: (2017)

Regio- and stereoselective biomimetic synthesis of oligostilbenoid dimers from resveratrol analogues: Influence of the solvent, oxidant, and substitution
by: Ibrahim Ali , Noorbatcha
Published: (2008)

HPLC separation and isolation of asiaticoside from Centella asiatica and its biotransformation by A. niger
by: Alfarra, Helmi Yousif, et al.
Published: (2014)

Biotransformation of ethyl p-methoxycinnamate from Kaempferia galanga L. using Aspergillus niger
by: Mohd Hasali, Nor Hazwani, et al.
Published: (2013)

Biotransformation of eugenol and isoeugenol to vanillin by Aspergillus Niger
by: Sasikala, Appalasuwami
Published: (2012)

A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid
by: Kumar, Raju Suresh, et al.
Published: (2016)

Stereoselective tetrahydrofuran synthesis
by: Shaw, Duncan Edward
Published: (1993)

Study on ω-fatty acids from Malaysian giant mudskipper (Periophthalmodon schlosseri) fish oil
by: Omar, Muhammad Nor, et al.
Published: (2010)

Stereoselective reduction of 1-benzyl-3,3-dimethyl-5-methylenepyrrolidine-2,4-dione using sodium borohydride with selected metal chlorides
by: Jumali, Nor Saliyana, et al.
Published: (2017)

Synthesis of 2-substituted 4(R)-hydroxy-2-cyclopenten-1-one, a prostaglandin intermediate with methyl oleate from palm oil
by: Omar, Muhammad Nor, et al.
Published: (2004)

Changes of headspace volatile constituents of palm olein and selected oils after frying French fries
by: Omar, Muhammad Nor, et al.
Published: (2007)

Solid phase microextraction analysis of volatile constituents of heated palm olein and selected oils
by: Omar, Muhammad Nor, et al.
Published: (2009)

Frying performance of palm-based solid frying shortening
by: Omar, Muhammad Nor, et al.
Published: (2010)

Stereoselective synthesis towards unnatural proline-based amino acids
by: Makhathini, S., et al.
Published: (2016)

Single molecule fluorescence spectroscopy
by: White,, JD, et al.
Published: (2002)

Molecules in a state of flux
by: Heard, Peter *
Published: (2018)

Supercritical fluid extraction (SFE) of Malaysian wild ginger Zingiber puberulum inflorescence
by: Omar, Muhammad Nor, et al.
Published: (2013)

Biotransformation of ethyl p-methoxycinnamate and cytotoxicity activity of its biotransformed product
by: Omar, Muhammad Nor, et al.
Published: (2016)

Novel Concept of Aligning the Molecules for Electronic Paper Displays
by: Hegde, Gurumurthy, et al.
Published: (2013)

Synthesis and characterization of carbon monoxide-releasing molecules (CORMS) as bioactive agents / Lee Shiaw Xian
by: Lee , Shiaw Xian
Published: (2021)

Deduction of the conformation of short chain luminescent conjugated polymers from single molecule photophysics
by: White, J
Published: (2001)

Quasiclassical trajectory study of six-centered bond exchange reaction between hydrogen molecules
by: Ibrahim Ali , Noorbatcha
Published: (1998)

Monte-carlo simulations of gas-phase collisions in rapid desorption of molecules from surfaces
by: Ibrahim Ali , Noorbatcha
Published: (1987)

Monte Carlo simulations of gas‐phase collisions in rapid desorption of molecules from surfaces
by: Ibrahim Ali , Noorbatcha, et al.
Published: (1987)

Effects of gas‐phase collisions in rapid desorption of molecules from surfaces in the presence of coadsorbates
by: Ibrahim Ali , Noorbatcha, et al.
Published: (1988)

Design and development of new zinc porphyrin molecules as high performing photoacoustic contrast agents
by: Yasin, Amina
Published: (2018)

Simultaneous determination of atenolol and chlorthalidone in pharmaceutical preparations by capillary-zone electrophoresis
by: Khaldun, Al-Azzam, et al.
Published: (2009)

Synthesis of Poly(hydroxamic acid) Ligand from Polymer Grafted Khaya Cellulose for Transition Metals Extraction
by: Lutfor, M. R., et al.
Published: (2016)

Biodiesel synthesis via solid acid catalyst by using palm fatty acid distillate (PFAD) as feedstock.
by: Liaw, Kai Jun
Published: (2013)

Synthesis and Characterization of Molecularly Imprinted Polymer with Oleic Acid as a Template
by: Siti Maizatul Ameera, Azhar, et al.
Published: (2022)

Competing supramolecular interactions in crystals of heavy-element compounds – a consideration of the energies of association between molecules
by: Tiekink, Edward R. T. *
Published: (2018)