Sterilisation effect study on granular hydroxyapatite (HA)

Hydroxyapatite is a calcium phosphate bioceramic that has been shown by many authors to be biocompatible with bioactive properties. It is widely accepted as the best synthetic material available for surgical use as a bone graft substitute. HA granules produced by AMREC-SIRIM from local materials und...

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Main Authors: Saidu, Mohd Fharid, Masri, Mashita, Khalid, Khadijah, Fazan, Fazilah, Khalid, Kamarul Ariffin
Format: Article
Language:English
English
Published: Malaysian Medical Association 2004
Subjects:
Online Access:http://irep.iium.edu.my/23911/
http://irep.iium.edu.my/23911/2/Sterilisation-effect-study-on-granular-hydroxyapatite-%28HA%29._2004_The-Medical-journal-of-Malaysia.htm
http://irep.iium.edu.my/23911/3/Sterilisation-effect-study-on-granular-hydroxyapatite-%28HA%29._2004_The-Medical-journal-of-Malaysia.htm
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author Saidu, Mohd Fharid
Masri, Mashita
Khalid, Khadijah
Fazan, Fazilah
Khalid, Kamarul Ariffin
author_facet Saidu, Mohd Fharid
Masri, Mashita
Khalid, Khadijah
Fazan, Fazilah
Khalid, Kamarul Ariffin
author_sort Saidu, Mohd Fharid
building IIUM Repository
collection Online Access
description Hydroxyapatite is a calcium phosphate bioceramic that has been shown by many authors to be biocompatible with bioactive properties. It is widely accepted as the best synthetic material available for surgical use as a bone graft substitute. HA granules produced by AMREC-SIRIM from local materials underwent 5 types of sterilisation techniques with different ageing periods. Samples were tested for chemical and phase composition and microbial contamination before and after being sterilised. From the microbiological tests done, none of the unsterilised positive control yielded a positive culture. Results from X-Ray diffraction studies found that all the sterilisation techniques did not chemically degrade or structurally change the HA granules significantly.
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last_indexed 2025-11-14T15:14:27Z
publishDate 2004
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spelling iium-239112013-04-12T08:20:59Z http://irep.iium.edu.my/23911/ Sterilisation effect study on granular hydroxyapatite (HA) Saidu, Mohd Fharid Masri, Mashita Khalid, Khadijah Fazan, Fazilah Khalid, Kamarul Ariffin RD701 Orthopedics Hydroxyapatite is a calcium phosphate bioceramic that has been shown by many authors to be biocompatible with bioactive properties. It is widely accepted as the best synthetic material available for surgical use as a bone graft substitute. HA granules produced by AMREC-SIRIM from local materials underwent 5 types of sterilisation techniques with different ageing periods. Samples were tested for chemical and phase composition and microbial contamination before and after being sterilised. From the microbiological tests done, none of the unsterilised positive control yielded a positive culture. Results from X-Ray diffraction studies found that all the sterilisation techniques did not chemically degrade or structurally change the HA granules significantly. Malaysian Medical Association 2004-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/23911/2/Sterilisation-effect-study-on-granular-hydroxyapatite-%28HA%29._2004_The-Medical-journal-of-Malaysia.htm application/pdf en http://irep.iium.edu.my/23911/3/Sterilisation-effect-study-on-granular-hydroxyapatite-%28HA%29._2004_The-Medical-journal-of-Malaysia.htm Saidu, Mohd Fharid and Masri, Mashita and Khalid, Khadijah and Fazan, Fazilah and Khalid, Kamarul Ariffin (2004) Sterilisation effect study on granular hydroxyapatite (HA). The Medical journal of Malaysia, 59 (Supp B). pp. 85-86. ISSN 0300-5283
spellingShingle RD701 Orthopedics
Saidu, Mohd Fharid
Masri, Mashita
Khalid, Khadijah
Fazan, Fazilah
Khalid, Kamarul Ariffin
Sterilisation effect study on granular hydroxyapatite (HA)
title Sterilisation effect study on granular hydroxyapatite (HA)
title_full Sterilisation effect study on granular hydroxyapatite (HA)
title_fullStr Sterilisation effect study on granular hydroxyapatite (HA)
title_full_unstemmed Sterilisation effect study on granular hydroxyapatite (HA)
title_short Sterilisation effect study on granular hydroxyapatite (HA)
title_sort sterilisation effect study on granular hydroxyapatite (ha)
topic RD701 Orthopedics
url http://irep.iium.edu.my/23911/
http://irep.iium.edu.my/23911/2/Sterilisation-effect-study-on-granular-hydroxyapatite-%28HA%29._2004_The-Medical-journal-of-Malaysia.htm
http://irep.iium.edu.my/23911/3/Sterilisation-effect-study-on-granular-hydroxyapatite-%28HA%29._2004_The-Medical-journal-of-Malaysia.htm