Pharmacogenetics of beta adrenergic blockers: their clinical significance
Beta adrenergic blockers are (ß-blockers) an important class of drugs for the treatment of various cardiovascular diseases, including hypertension, angina pectoris, arrhythmias, hypertrophic cardiomyopathy, and heart failure. They are also indicated for the treatment of migraine headache, anxiety, t...
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| Format: | Article |
| Language: | English |
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USM
2009
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| Online Access: | http://irep.iium.edu.my/22234/ http://irep.iium.edu.my/22234/1/Buletin_no.4.pdf |
| _version_ | 1848778979278848000 |
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| author | Elsayed, Tarek Mohamed Ali |
| author_facet | Elsayed, Tarek Mohamed Ali |
| author_sort | Elsayed, Tarek Mohamed Ali |
| building | IIUM Repository |
| collection | Online Access |
| description | Beta adrenergic blockers are (ß-blockers) an important class of drugs for the treatment of various cardiovascular diseases, including hypertension, angina pectoris, arrhythmias, hypertrophic cardiomyopathy, and heart failure. They are also indicated for the treatment of migraine headache, anxiety, tremor, and glaucoma. Individual and ethnic variability has been noted in clinical practice and reported in clinical trials. Many factors are anticipated to affect the extent of variability of response to β-blockers including pharmacodynamic variability and pharmacokinetic variability of the parent compounds, as well as, active constituents. In this review, we will present the studies that examine the effect of genetic variability on the pharmacodynamics of β-blockers. |
| first_indexed | 2025-11-14T15:10:29Z |
| format | Article |
| id | iium-22234 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:10:29Z |
| publishDate | 2009 |
| publisher | USM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-222342016-11-06T04:31:08Z http://irep.iium.edu.my/22234/ Pharmacogenetics of beta adrenergic blockers: their clinical significance Elsayed, Tarek Mohamed Ali RM300 Drugs and their action Beta adrenergic blockers are (ß-blockers) an important class of drugs for the treatment of various cardiovascular diseases, including hypertension, angina pectoris, arrhythmias, hypertrophic cardiomyopathy, and heart failure. They are also indicated for the treatment of migraine headache, anxiety, tremor, and glaucoma. Individual and ethnic variability has been noted in clinical practice and reported in clinical trials. Many factors are anticipated to affect the extent of variability of response to β-blockers including pharmacodynamic variability and pharmacokinetic variability of the parent compounds, as well as, active constituents. In this review, we will present the studies that examine the effect of genetic variability on the pharmacodynamics of β-blockers. USM 2009-12 Article NonPeerReviewed application/pdf en http://irep.iium.edu.my/22234/1/Buletin_no.4.pdf Elsayed, Tarek Mohamed Ali (2009) Pharmacogenetics of beta adrenergic blockers: their clinical significance. INFORMM: Postgraduate Bulletin, 1 (4). pp. 20-23. ISSN 2180-1959 http://www.informm.usm.my/index.php/en/ |
| spellingShingle | RM300 Drugs and their action Elsayed, Tarek Mohamed Ali Pharmacogenetics of beta adrenergic blockers: their clinical significance |
| title | Pharmacogenetics of beta adrenergic blockers: their clinical significance |
| title_full | Pharmacogenetics of beta adrenergic blockers: their clinical significance |
| title_fullStr | Pharmacogenetics of beta adrenergic blockers: their clinical significance |
| title_full_unstemmed | Pharmacogenetics of beta adrenergic blockers: their clinical significance |
| title_short | Pharmacogenetics of beta adrenergic blockers: their clinical significance |
| title_sort | pharmacogenetics of beta adrenergic blockers: their clinical significance |
| topic | RM300 Drugs and their action |
| url | http://irep.iium.edu.my/22234/ http://irep.iium.edu.my/22234/ http://irep.iium.edu.my/22234/1/Buletin_no.4.pdf |