Screening anti-cancer compounds from medicinal Malaysian plants

In the fight against cancer. no,·el chemotherapeutic agems arc constanlly being sought to complement cxisting dTlJlls. In this study. 110-10 methanolic cxtracts prepared from seven tropical plants "'ith. eth.nomedical uses were tesled for th.eir c)'loto~ic ability in "itro agains...

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Main Authors: Ahmad Raus, Raha, Johari, Yusuf, Amid, Azura
Format: Book Chapter
Language:English
Published: IIUM Press 2011
Subjects:
Online Access:http://irep.iium.edu.my/20819/
http://irep.iium.edu.my/20819/1/SCREENING_ANTI-CANCER_COMPOUNDS_FROM_MEDICINAL_MALAYSIAN_PLANTS.pdf
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author Ahmad Raus, Raha
Johari, Yusuf
Amid, Azura
author_facet Ahmad Raus, Raha
Johari, Yusuf
Amid, Azura
author_sort Ahmad Raus, Raha
building IIUM Repository
collection Online Access
description In the fight against cancer. no,·el chemotherapeutic agems arc constanlly being sought to complement cxisting dTlJlls. In this study. 110-10 methanolic cxtracts prepared from seven tropical plants "'ith. eth.nomedical uses were tesled for th.eir c)'loto~ic ability in "itro against cancer cell lines. The plants studied were Carico papaya (papaya). Co/l'Ils bl"ml'i (ali·ati), Cosmos calldalll)· (uJam raja). "-'CIIS deltoidea (rna. OOlek), Pip"I" sm·WIIII/VSIIIll (kaduk), PIIle/'M indica (beluntas), and l'I"emlllu curdifloru (bcbuas). The c)'lolOxicity screening tesl, SRB (sulforhodamine B) was calTied out to detennine plants wilh potential amicancer properties. Results indicated that P. sonuentosllflI and P. cordijloru exlracis dcmonslr4[OO signifiean[ c)'101oxicily against MCn cell line where the IC", were 125 ilgfml and 113 ilgfmL. respectively, and a[ the same lime: showed less aclh-ilies against nonnal cells. Wilh re:spc:ct [0 Ihese results, P. sarmenflUum and P. r:ordif/oro eX!T1lCIS could be studied further fOJ [heir po[enlialto lTeal cance-r.
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institution International Islamic University Malaysia
institution_category Local University
language English
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spelling iium-208192012-11-26T07:30:31Z http://irep.iium.edu.my/20819/ Screening anti-cancer compounds from medicinal Malaysian plants Ahmad Raus, Raha Johari, Yusuf Amid, Azura TP Chemical technology TP248.13 Biotechnology In the fight against cancer. no,·el chemotherapeutic agems arc constanlly being sought to complement cxisting dTlJlls. In this study. 110-10 methanolic cxtracts prepared from seven tropical plants "'ith. eth.nomedical uses were tesled for th.eir c)'loto~ic ability in "itro against cancer cell lines. The plants studied were Carico papaya (papaya). Co/l'Ils bl"ml'i (ali·ati), Cosmos calldalll)· (uJam raja). "-'CIIS deltoidea (rna. OOlek), Pip"I" sm·WIIII/VSIIIll (kaduk), PIIle/'M indica (beluntas), and l'I"emlllu curdifloru (bcbuas). The c)'lolOxicity screening tesl, SRB (sulforhodamine B) was calTied out to detennine plants wilh potential amicancer properties. Results indicated that P. sonuentosllflI and P. cordijloru exlracis dcmonslr4[OO signifiean[ c)'101oxicily against MCn cell line where the IC", were 125 ilgfml and 113 ilgfmL. respectively, and a[ the same lime: showed less aclh-ilies against nonnal cells. Wilh re:spc:ct [0 Ihese results, P. sarmenflUum and P. r:ordif/oro eX!T1lCIS could be studied further fOJ [heir po[enlialto lTeal cance-r. IIUM Press 2011 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/20819/1/SCREENING_ANTI-CANCER_COMPOUNDS_FROM_MEDICINAL_MALAYSIAN_PLANTS.pdf Ahmad Raus, Raha and Johari, Yusuf and Amid, Azura (2011) Screening anti-cancer compounds from medicinal Malaysian plants. In: Current Research and Development in Biotechnology Engineering at IIUM (volume II). IIUM Press, Kuala Lumpur, pp. 332-337. ISBN 978-967-418-151-2 http://rms.research.iium.edu.my/bookstore/default.aspx
spellingShingle TP Chemical technology
TP248.13 Biotechnology
Ahmad Raus, Raha
Johari, Yusuf
Amid, Azura
Screening anti-cancer compounds from medicinal Malaysian plants
title Screening anti-cancer compounds from medicinal Malaysian plants
title_full Screening anti-cancer compounds from medicinal Malaysian plants
title_fullStr Screening anti-cancer compounds from medicinal Malaysian plants
title_full_unstemmed Screening anti-cancer compounds from medicinal Malaysian plants
title_short Screening anti-cancer compounds from medicinal Malaysian plants
title_sort screening anti-cancer compounds from medicinal malaysian plants
topic TP Chemical technology
TP248.13 Biotechnology
url http://irep.iium.edu.my/20819/
http://irep.iium.edu.my/20819/
http://irep.iium.edu.my/20819/1/SCREENING_ANTI-CANCER_COMPOUNDS_FROM_MEDICINAL_MALAYSIAN_PLANTS.pdf