Blood pressure variability in patients with diabetes mellitus
Reduced arterial compliance in patients with diabetes mellitus has been shown in several studies, but it has not been significantly associated with either atherosclerosis or vessel wall thickness. Blood pressure variability is still poorly explored in diabetic patients. The aim of this study was to...
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| Format: | Article |
| Language: | English |
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SAGE Publications
2010
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| Online Access: | http://irep.iium.edu.my/19015/ http://irep.iium.edu.my/19015/1/blood_pressure_variability_in_patients.pdf |
| _version_ | 1848778292806549504 |
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| author | Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah |
| author_facet | Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah |
| author_sort | Mokhtar, Rafidah Hanim |
| building | IIUM Repository |
| collection | Online Access |
| description | Reduced arterial compliance in patients with diabetes mellitus has been shown in several studies, but it has not been significantly associated with either atherosclerosis or vessel wall thickness. Blood pressure variability is still poorly explored in diabetic patients. The aim of this study was to compare blood pressure variability and arterial compliance in patients with type 2 diabetes mellitus and controls matched for sex, age, and weight. Arterial compliance was measured and noninvasive 24-h ambulatory blood pressure monitoring was performed in 18 diabetic patients and 18 controls. There was significantly higher 24-h systolic blood pressure variability (17.7 ± 6.8 vs. 14.6 ± 2.6 mm Hg), diastolic blood pressure variability (15.6 ± 7.1 vs. 11.4 ± 3.1 mm Hg), and mean arterial blood pressure variability (14.8 ± 7.0 vs. 11.1 ± 2.9) in diabetic patients. Systolic, diastolic, and mean arterial blood pressure variability was significantly higher during daytime but not night time in diabetic patients compared to controls. Diabetic patients also had significantly reduced small artery compliance, but no differences in large artery compliance, cardiac output, or systemic vascular resistance. The findings suggest that hyperglycemia may affect the compliance of the vascular system, resulting in high blood pressure fluctuations. |
| first_indexed | 2025-11-14T14:59:34Z |
| format | Article |
| id | iium-19015 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:59:34Z |
| publishDate | 2010 |
| publisher | SAGE Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-190152016-11-12T04:03:37Z http://irep.iium.edu.my/19015/ Blood pressure variability in patients with diabetes mellitus Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah RC Internal medicine Reduced arterial compliance in patients with diabetes mellitus has been shown in several studies, but it has not been significantly associated with either atherosclerosis or vessel wall thickness. Blood pressure variability is still poorly explored in diabetic patients. The aim of this study was to compare blood pressure variability and arterial compliance in patients with type 2 diabetes mellitus and controls matched for sex, age, and weight. Arterial compliance was measured and noninvasive 24-h ambulatory blood pressure monitoring was performed in 18 diabetic patients and 18 controls. There was significantly higher 24-h systolic blood pressure variability (17.7 ± 6.8 vs. 14.6 ± 2.6 mm Hg), diastolic blood pressure variability (15.6 ± 7.1 vs. 11.4 ± 3.1 mm Hg), and mean arterial blood pressure variability (14.8 ± 7.0 vs. 11.1 ± 2.9) in diabetic patients. Systolic, diastolic, and mean arterial blood pressure variability was significantly higher during daytime but not night time in diabetic patients compared to controls. Diabetic patients also had significantly reduced small artery compliance, but no differences in large artery compliance, cardiac output, or systemic vascular resistance. The findings suggest that hyperglycemia may affect the compliance of the vascular system, resulting in high blood pressure fluctuations. SAGE Publications 2010-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/19015/1/blood_pressure_variability_in_patients.pdf Mokhtar, Rafidah Hanim and Ayob, Azizi and Mohd Noor, Noriah (2010) Blood pressure variability in patients with diabetes mellitus. Asian Cardiovascular and Thoracic Annals , 18 (4). pp. 344-348. ISSN 0218-4923 http://asianannals.ctsnetjournals.org/cgi/content/abstract/18/4/344 |
| spellingShingle | RC Internal medicine Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah Blood pressure variability in patients with diabetes mellitus |
| title | Blood pressure variability in patients with diabetes mellitus
|
| title_full | Blood pressure variability in patients with diabetes mellitus
|
| title_fullStr | Blood pressure variability in patients with diabetes mellitus
|
| title_full_unstemmed | Blood pressure variability in patients with diabetes mellitus
|
| title_short | Blood pressure variability in patients with diabetes mellitus
|
| title_sort | blood pressure variability in patients with diabetes mellitus |
| topic | RC Internal medicine |
| url | http://irep.iium.edu.my/19015/ http://irep.iium.edu.my/19015/ http://irep.iium.edu.my/19015/1/blood_pressure_variability_in_patients.pdf |