Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective

The oral route is considered the most patient-convenient means of drug administration. In recent years there has been a tendency to employ smart carrier systems that enable controlled or timed release of a bioactive material, thereby providing a better dosing pattern and minimizing side effects. Nan...

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Main Authors: F., Heidarpour, M.R, Mohammadabadi, Sarker, Md. Zaidul Islam, B., Maherani, N., Saari, A.A, Hamid, F., Abas, M.Y.A, Manap, M.R, Mozafari
Format: Article
Language:English
Published: Govi Verlag Pharmazeutischer Verlag GmbH 2011
Subjects:
Online Access:http://irep.iium.edu.my/18655/
http://irep.iium.edu.my/18655/1/sarker.pdf
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author F., Heidarpour
M.R, Mohammadabadi
Sarker, Md. Zaidul Islam
B., Maherani
N., Saari
A.A, Hamid
F., Abas
M.Y.A, Manap
M.R, Mozafari
author_facet F., Heidarpour
M.R, Mohammadabadi
Sarker, Md. Zaidul Islam
B., Maherani
N., Saari
A.A, Hamid
F., Abas
M.Y.A, Manap
M.R, Mozafari
author_sort F., Heidarpour
building IIUM Repository
collection Online Access
description The oral route is considered the most patient-convenient means of drug administration. In recent years there has been a tendency to employ smart carrier systems that enable controlled or timed release of a bioactive material, thereby providing a better dosing pattern and minimizing side effects. Nano-encapsulation systems (nanocarriers) offer important advantages over conventional drug delivery techniques. Nanocarriers can protect the drug from chemical/enzymatic degradation and enhance bioavailability. Prebiotics are ideal ingredients for the nano-encapsulation and oral drug delivery due to their natural ability to protect the encapsulated compound in the upper gasterointestinal (GI) tract. Here the potential of prebiotics for oral delivery of drugs and other bioactives is reviewed.
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language English
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publishDate 2011
publisher Govi Verlag Pharmazeutischer Verlag GmbH
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spelling iium-186552013-12-05T08:29:15Z http://irep.iium.edu.my/18655/ Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective F., Heidarpour M.R, Mohammadabadi Sarker, Md. Zaidul Islam B., Maherani N., Saari A.A, Hamid F., Abas M.Y.A, Manap M.R, Mozafari RM300 Drugs and their action TP Chemical technology The oral route is considered the most patient-convenient means of drug administration. In recent years there has been a tendency to employ smart carrier systems that enable controlled or timed release of a bioactive material, thereby providing a better dosing pattern and minimizing side effects. Nano-encapsulation systems (nanocarriers) offer important advantages over conventional drug delivery techniques. Nanocarriers can protect the drug from chemical/enzymatic degradation and enhance bioavailability. Prebiotics are ideal ingredients for the nano-encapsulation and oral drug delivery due to their natural ability to protect the encapsulated compound in the upper gasterointestinal (GI) tract. Here the potential of prebiotics for oral delivery of drugs and other bioactives is reviewed. Govi Verlag Pharmazeutischer Verlag GmbH 2011-05-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/18655/1/sarker.pdf F., Heidarpour and M.R, Mohammadabadi and Sarker, Md. Zaidul Islam and B., Maherani and N., Saari and A.A, Hamid and F., Abas and M.Y.A, Manap and M.R, Mozafari (2011) Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective. Die Pharmazie -International Journal of Pharmaceutical Sciences, 66 (5). pp. 319-324. ISSN 0031-7144 http://dx.doi.org/10.1691/ph.2011.0279
spellingShingle RM300 Drugs and their action
TP Chemical technology
F., Heidarpour
M.R, Mohammadabadi
Sarker, Md. Zaidul Islam
B., Maherani
N., Saari
A.A, Hamid
F., Abas
M.Y.A, Manap
M.R, Mozafari
Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective
title Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective
title_full Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective
title_fullStr Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective
title_full_unstemmed Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective
title_short Use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective
title_sort use of prebiotics in oral delivery of bioactive compounds: a nanotechnology perspective
topic RM300 Drugs and their action
TP Chemical technology
url http://irep.iium.edu.my/18655/
http://irep.iium.edu.my/18655/
http://irep.iium.edu.my/18655/1/sarker.pdf