Anti-inflammatory compounds of macro algae origin: A review
Inflammation, occurs frequently in living tissues, and is responsible for numerous death and precursor to some deadly diseases. This review focus on seaweed derived anti-inflammatory compounds, which have attracted interest and promising replacer of current anti-inflammatory drugs. Macro algae hav...
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| Format: | Article |
| Language: | English |
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Academic Journals
2011
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| Online Access: | http://irep.iium.edu.my/17155/ http://irep.iium.edu.my/17155/1/Jaswir_and_Monsur-jmpr_2011.pdf |
| _version_ | 1848778001162960896 |
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| author | Jaswir, Irwandi A. Monsur, Hammed |
| author_facet | Jaswir, Irwandi A. Monsur, Hammed |
| author_sort | Jaswir, Irwandi |
| building | IIUM Repository |
| collection | Online Access |
| description | Inflammation, occurs frequently in living tissues, and is responsible for numerous death and precursor
to some deadly diseases. This review focus on seaweed derived anti-inflammatory compounds, which
have attracted interest and promising replacer of current anti-inflammatory drugs. Macro algae have
both pro- and anti-inflammatory compounds, the later include sulphated polysaccharides (fucoidans)
from brown seaweeds, alkaloids (Caulerpin I, II and III) from red and green seaweeds, polyunsaturated
fatty acids (Docosahexaenoic acid: EDA, Eicosapentaenoic acid: EPA, Stearidonic acid: SA and
Eicosatrienoic acid: ETA), carotenoids (fucoxanthin and astaxanthin), Pheophytin A and Vidalols A and
B. Anti-inflammatory assays include edema, erythema, tumor necrosis factor (TNF-α), interleukin (IL 1β,
6, 8), Nitric oxide (NO), inducible Nitric oxide synthase (iNOS), Prostaglandin E (PGE 2 and 3),
Cyclooxygenase (COX-2), transcription factor (NF-κB) and leukotrienes (LB 3 and 4). Although, in-vivo
and in-vitro studies have been done for crude extracts and specific compounds, but some compounds
have not analysed in-vitro, and investigation of their pathway need to be studied. |
| first_indexed | 2025-11-14T14:54:56Z |
| format | Article |
| id | iium-17155 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:54:56Z |
| publishDate | 2011 |
| publisher | Academic Journals |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-171552016-08-24T00:55:50Z http://irep.iium.edu.my/17155/ Anti-inflammatory compounds of macro algae origin: A review Jaswir, Irwandi A. Monsur, Hammed QD Chemistry Inflammation, occurs frequently in living tissues, and is responsible for numerous death and precursor to some deadly diseases. This review focus on seaweed derived anti-inflammatory compounds, which have attracted interest and promising replacer of current anti-inflammatory drugs. Macro algae have both pro- and anti-inflammatory compounds, the later include sulphated polysaccharides (fucoidans) from brown seaweeds, alkaloids (Caulerpin I, II and III) from red and green seaweeds, polyunsaturated fatty acids (Docosahexaenoic acid: EDA, Eicosapentaenoic acid: EPA, Stearidonic acid: SA and Eicosatrienoic acid: ETA), carotenoids (fucoxanthin and astaxanthin), Pheophytin A and Vidalols A and B. Anti-inflammatory assays include edema, erythema, tumor necrosis factor (TNF-α), interleukin (IL 1β, 6, 8), Nitric oxide (NO), inducible Nitric oxide synthase (iNOS), Prostaglandin E (PGE 2 and 3), Cyclooxygenase (COX-2), transcription factor (NF-κB) and leukotrienes (LB 3 and 4). Although, in-vivo and in-vitro studies have been done for crude extracts and specific compounds, but some compounds have not analysed in-vitro, and investigation of their pathway need to be studied. Academic Journals 2011-12-31 Article PeerReviewed application/pdf en http://irep.iium.edu.my/17155/1/Jaswir_and_Monsur-jmpr_2011.pdf Jaswir, Irwandi and A. Monsur, Hammed (2011) Anti-inflammatory compounds of macro algae origin: A review. Journal of Medicinal Plants Research, 5 (33). pp. 7146-7154. ISSN 1996-0875 http://www.academicjournals.org/JMPR/PDF/pdf2011/31Dec/Jaswir%20and%20Monsur.pdf 10.5897/JMPR11.018 |
| spellingShingle | QD Chemistry Jaswir, Irwandi A. Monsur, Hammed Anti-inflammatory compounds of macro algae origin: A review |
| title | Anti-inflammatory compounds of macro algae origin: A review |
| title_full | Anti-inflammatory compounds of macro algae origin: A review |
| title_fullStr | Anti-inflammatory compounds of macro algae origin: A review |
| title_full_unstemmed | Anti-inflammatory compounds of macro algae origin: A review |
| title_short | Anti-inflammatory compounds of macro algae origin: A review |
| title_sort | anti-inflammatory compounds of macro algae origin: a review |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/17155/ http://irep.iium.edu.my/17155/ http://irep.iium.edu.my/17155/ http://irep.iium.edu.my/17155/1/Jaswir_and_Monsur-jmpr_2011.pdf |