Formulation of topical dosage form of Pangasius sutchi and their wound healing activities

Fish oil is associated with many promising health benefit since it contains an essential fatty acid called ω fatty acid (1, 2). This experiment was conducted to study the effect of fish oil containing ω -3 fatty acids on wound healing. A freshwater fish, Pangasius sutchi was used to extract its oil...

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Main Authors: Omar, Muhammad Nor, Hajazi, Nurhani Fadzil, Zuberdi, Ahmad Muzammil, Ahmad, Kausar
Format: Proceeding Paper
Language:English
English
Published: 2011
Subjects:
Online Access:http://irep.iium.edu.my/17037/
http://irep.iium.edu.my/17037/2/DR_NO_NNS2011_Abstract.pdf
http://irep.iium.edu.my/17037/1/NNS_2011_Bali.pdf
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author Omar, Muhammad Nor
Hajazi, Nurhani Fadzil
Zuberdi, Ahmad Muzammil
Ahmad, Kausar
author_facet Omar, Muhammad Nor
Hajazi, Nurhani Fadzil
Zuberdi, Ahmad Muzammil
Ahmad, Kausar
author_sort Omar, Muhammad Nor
building IIUM Repository
collection Online Access
description Fish oil is associated with many promising health benefit since it contains an essential fatty acid called ω fatty acid (1, 2). This experiment was conducted to study the effect of fish oil containing ω -3 fatty acids on wound healing. A freshwater fish, Pangasius sutchi was used to extract its oil using a modified Folch method (3). The fatty acid profile of the fish oil was determined using a GC/MS instrument (2,4). A topical cream containing the fish oil extract was formulated and stability test including particle size analysis were carried out. The formulated cream was tested on Sprague Dawley rats for wound healing properties. A hole was punctured at the back of the rat’s neck using biopsy punch and cream was applied twice daily. The diameter of the wound was recorded every two days. It was found that the topical cream containing P. sutchi oil exhibited wound healing properties, however, the time taken for the rat’s wound to heal was not significantly different from the control groups.
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format Proceeding Paper
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institution International Islamic University Malaysia
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language English
English
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publishDate 2011
recordtype eprints
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spelling iium-170372012-03-08T00:44:28Z http://irep.iium.edu.my/17037/ Formulation of topical dosage form of Pangasius sutchi and their wound healing activities Omar, Muhammad Nor Hajazi, Nurhani Fadzil Zuberdi, Ahmad Muzammil Ahmad, Kausar Q Science (General) Fish oil is associated with many promising health benefit since it contains an essential fatty acid called ω fatty acid (1, 2). This experiment was conducted to study the effect of fish oil containing ω -3 fatty acids on wound healing. A freshwater fish, Pangasius sutchi was used to extract its oil using a modified Folch method (3). The fatty acid profile of the fish oil was determined using a GC/MS instrument (2,4). A topical cream containing the fish oil extract was formulated and stability test including particle size analysis were carried out. The formulated cream was tested on Sprague Dawley rats for wound healing properties. A hole was punctured at the back of the rat’s neck using biopsy punch and cream was applied twice daily. The diameter of the wound was recorded every two days. It was found that the topical cream containing P. sutchi oil exhibited wound healing properties, however, the time taken for the rat’s wound to heal was not significantly different from the control groups. 2011-09-23 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/17037/2/DR_NO_NNS2011_Abstract.pdf application/pdf en http://irep.iium.edu.my/17037/1/NNS_2011_Bali.pdf Omar, Muhammad Nor and Hajazi, Nurhani Fadzil and Zuberdi, Ahmad Muzammil and Ahmad, Kausar (2011) Formulation of topical dosage form of Pangasius sutchi and their wound healing activities. In: 4th International Nanoscience and Nanotechnology Symposium (NNS2011), 23-25 September 2011, Bali, Indonesia.
spellingShingle Q Science (General)
Omar, Muhammad Nor
Hajazi, Nurhani Fadzil
Zuberdi, Ahmad Muzammil
Ahmad, Kausar
Formulation of topical dosage form of Pangasius sutchi and their wound healing activities
title Formulation of topical dosage form of Pangasius sutchi and their wound healing activities
title_full Formulation of topical dosage form of Pangasius sutchi and their wound healing activities
title_fullStr Formulation of topical dosage form of Pangasius sutchi and their wound healing activities
title_full_unstemmed Formulation of topical dosage form of Pangasius sutchi and their wound healing activities
title_short Formulation of topical dosage form of Pangasius sutchi and their wound healing activities
title_sort formulation of topical dosage form of pangasius sutchi and their wound healing activities
topic Q Science (General)
url http://irep.iium.edu.my/17037/
http://irep.iium.edu.my/17037/2/DR_NO_NNS2011_Abstract.pdf
http://irep.iium.edu.my/17037/1/NNS_2011_Bali.pdf