Some biological activities of Malaysian leech salive extract
Leeches were fed on the phagostimulatory solution through parafilm membrane. The satiated leeches were forced to regurgitate the solution by soaking them in an ice-container. The anticoagulant activity was ascertained using thrombin time assay (TT). The result revealed that the saliva concentration...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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IIUM Press
2011
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| Online Access: | http://irep.iium.edu.my/16870/ http://irep.iium.edu.my/16870/1/some_biological.pdf |
| _version_ | 1848777957959532544 |
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| author | M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed |
| author_facet | M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed |
| author_sort | M.Abdualkader, Abdualrahman |
| building | IIUM Repository |
| collection | Online Access |
| description | Leeches were fed on the phagostimulatory solution through parafilm membrane. The satiated leeches were forced to regurgitate the solution by soaking them in an ice-container. The anticoagulant activity was ascertained using thrombin time assay (TT). The result revealed that the saliva concentration which increases TT by 100% (IC100) is 43.205 μg/ml plasma. The antimicrobial activity of the saliva was tested against several bacterial spp. (E. coli, P. aeruginosa, B. cereus, Sal. typhi and S. aureus) and
fungi spp. (C.albicans and C.neoformans). It was found that saliva has an inhibition activity against Sal. typhi (minimal inhibitory concentration MIC 78.253 μg/ml),
S.aureus (MIC 78.253 μg/ml) and E .coli (MIC 121.256 μg/ml). |
| first_indexed | 2025-11-14T14:54:15Z |
| format | Article |
| id | iium-16870 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:54:15Z |
| publishDate | 2011 |
| publisher | IIUM Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-168702012-01-25T10:36:19Z http://irep.iium.edu.my/16870/ Some biological activities of Malaysian leech salive extract M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed R Medicine (General) Leeches were fed on the phagostimulatory solution through parafilm membrane. The satiated leeches were forced to regurgitate the solution by soaking them in an ice-container. The anticoagulant activity was ascertained using thrombin time assay (TT). The result revealed that the saliva concentration which increases TT by 100% (IC100) is 43.205 μg/ml plasma. The antimicrobial activity of the saliva was tested against several bacterial spp. (E. coli, P. aeruginosa, B. cereus, Sal. typhi and S. aureus) and fungi spp. (C.albicans and C.neoformans). It was found that saliva has an inhibition activity against Sal. typhi (minimal inhibitory concentration MIC 78.253 μg/ml), S.aureus (MIC 78.253 μg/ml) and E .coli (MIC 121.256 μg/ml). IIUM Press 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/16870/1/some_biological.pdf M.Abdualkader, Abdualrahman and Merzouk, Ahmed and Mohammed Ghawi, Abbas and Alaama, Mohammed (2011) Some biological activities of Malaysian leech salive extract. IIUM Engineering Journal, 12 (4). pp. 1-9. ISSN 1511-788X http://www.iium.edu.my/ejournal/index.php/iiumej/article/view/156/196 |
| spellingShingle | R Medicine (General) M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed Some biological activities of Malaysian leech salive extract |
| title | Some biological activities of Malaysian leech salive extract |
| title_full | Some biological activities of Malaysian leech salive extract |
| title_fullStr | Some biological activities of Malaysian leech salive extract |
| title_full_unstemmed | Some biological activities of Malaysian leech salive extract |
| title_short | Some biological activities of Malaysian leech salive extract |
| title_sort | some biological activities of malaysian leech salive extract |
| topic | R Medicine (General) |
| url | http://irep.iium.edu.my/16870/ http://irep.iium.edu.my/16870/ http://irep.iium.edu.my/16870/1/some_biological.pdf |