The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients

Secondary Sjogrens syndrome (sSs) is one of the autoimmune diseases that are covered by a big term Rheumatoid Arthritis (RA). Estrogen level was measured for both secondary Sjogren`s syndrome (sSs) and control females, anti Ro (SSA) & anti La (SSB) tests were also measured for sSs patients. the...

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Main Authors: Mustafa Al-Ahmad, Basma Ezzat, Mustafa, Nazih Shaban, Kashmola, Muhanad Ali Hamdon, Khalil, Raida W.
Format: Article
Language:English
Published: EuroJournals Publishing 2009
Subjects:
Online Access:http://irep.iium.edu.my/14563/
http://irep.iium.edu.my/14563/1/EJSR_31_2_02.pdf
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author Mustafa Al-Ahmad, Basma Ezzat
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
Khalil, Raida W.
author_facet Mustafa Al-Ahmad, Basma Ezzat
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
Khalil, Raida W.
author_sort Mustafa Al-Ahmad, Basma Ezzat
building IIUM Repository
collection Online Access
description Secondary Sjogrens syndrome (sSs) is one of the autoimmune diseases that are covered by a big term Rheumatoid Arthritis (RA). Estrogen level was measured for both secondary Sjogren`s syndrome (sSs) and control females, anti Ro (SSA) & anti La (SSB) tests were also measured for sSs patients. the aim of this study was to find out the relation between the elevation in estrogen level and one of the serious autoimmune diseases which is Ss especially in the secondary type (in the presence of the positive results of SSA &SSB) and to clarify the reason of the high incidence of this disease in female than in male. Twenty nine females patients age range (25-40) suffering from sSs and twenty control(healthy females age between 20-35) were involved in this study. This study showed that estrogen level was significantly higher (p≤0.01) in sSs patients comparing to normal control group, with higher percentage of positive results in anti-Ro (SSA) compared to anti- La (SSB). Increase of estrogen level in sSs female may be the explanation of high incidence of sSs in females. Accordingly, Anti-Ro cause antibodies are more specific to sSs patients than anti- La.
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spelling iium-145632015-11-24T00:03:56Z http://irep.iium.edu.my/14563/ The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Khalil, Raida W. R Medicine (General) Secondary Sjogrens syndrome (sSs) is one of the autoimmune diseases that are covered by a big term Rheumatoid Arthritis (RA). Estrogen level was measured for both secondary Sjogren`s syndrome (sSs) and control females, anti Ro (SSA) & anti La (SSB) tests were also measured for sSs patients. the aim of this study was to find out the relation between the elevation in estrogen level and one of the serious autoimmune diseases which is Ss especially in the secondary type (in the presence of the positive results of SSA &SSB) and to clarify the reason of the high incidence of this disease in female than in male. Twenty nine females patients age range (25-40) suffering from sSs and twenty control(healthy females age between 20-35) were involved in this study. This study showed that estrogen level was significantly higher (p≤0.01) in sSs patients comparing to normal control group, with higher percentage of positive results in anti-Ro (SSA) compared to anti- La (SSB). Increase of estrogen level in sSs female may be the explanation of high incidence of sSs in females. Accordingly, Anti-Ro cause antibodies are more specific to sSs patients than anti- La. EuroJournals Publishing 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/14563/1/EJSR_31_2_02.pdf Mustafa Al-Ahmad, Basma Ezzat and Mustafa, Nazih Shaban and Kashmola, Muhanad Ali Hamdon and Khalil, Raida W. (2009) The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients. European Journal of Scientific Research, 31 (2). pp. 184-187. ISSN 1450-216X
spellingShingle R Medicine (General)
Mustafa Al-Ahmad, Basma Ezzat
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
Khalil, Raida W.
The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients
title The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients
title_full The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients
title_fullStr The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients
title_full_unstemmed The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients
title_short The relation between estrogen level, anti-Ro (SSA), anti-La (SSB) & secondary Sjogren's syndrome patients
title_sort relation between estrogen level, anti-ro (ssa), anti-la (ssb) & secondary sjogren's syndrome patients
topic R Medicine (General)
url http://irep.iium.edu.my/14563/
http://irep.iium.edu.my/14563/1/EJSR_31_2_02.pdf