Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study
Dilated intercellular spaces (DIS) in prickle cell layers are considered as early signs of acid damage to the esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The ai...
| Main Authors: | , |
|---|---|
| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2011
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/13252/ http://irep.iium.edu.my/13252/1/oral_presentation_2011.pdf |
| _version_ | 1848777541776572416 |
|---|---|
| author | Myint, Yi Yi Tun, Ye |
| author_facet | Myint, Yi Yi Tun, Ye |
| author_sort | Myint, Yi Yi |
| building | IIUM Repository |
| collection | Online Access |
| description | Dilated intercellular spaces (DIS) in prickle cell layers are considered as early signs of acid damage to the esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore cellular attachments in most superficial esophageal cells of non- erosive (NERD) patients. The study group included 8 (NERD) patients and 5 normal controls. Specimens were routinely processed for SEM. The nature of cellular attachment and intercellular spaces between superficial cells of esophageal mucosa were viewed by SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings supported the concept of abnormal tissue resistance in pathogenesis of NERD patients.
Key words: Non-erosive Reflux Disease (NERD), Dilatation Intercellular spaces (DIS), scanning electron microscopy (SEM)
|
| first_indexed | 2025-11-14T14:47:38Z |
| format | Proceeding Paper |
| id | iium-13252 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:47:38Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-132522017-06-21T06:24:09Z http://irep.iium.edu.my/13252/ Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study Myint, Yi Yi Tun, Ye QM Human anatomy Dilated intercellular spaces (DIS) in prickle cell layers are considered as early signs of acid damage to the esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore cellular attachments in most superficial esophageal cells of non- erosive (NERD) patients. The study group included 8 (NERD) patients and 5 normal controls. Specimens were routinely processed for SEM. The nature of cellular attachment and intercellular spaces between superficial cells of esophageal mucosa were viewed by SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings supported the concept of abnormal tissue resistance in pathogenesis of NERD patients. Key words: Non-erosive Reflux Disease (NERD), Dilatation Intercellular spaces (DIS), scanning electron microscopy (SEM) 2011-12-21 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/13252/1/oral_presentation_2011.pdf Myint, Yi Yi and Tun, Ye (2011) Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study. In: 20th Scientific Conference of Microscopy Society of Malaysia , 20th to 22nd December 2011, Permaisuri resort, Port Dickson. (Unpublished) http://online.nuclearmalaysia.gov.my/sems/emsm2011/ |
| spellingShingle | QM Human anatomy Myint, Yi Yi Tun, Ye Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study |
| title | Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study |
| title_full | Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study |
| title_fullStr | Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study |
| title_full_unstemmed | Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study |
| title_short | Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study |
| title_sort | esophageal surface cells in non-erosive reflux disease (nerd): scanning electron microscopic study |
| topic | QM Human anatomy |
| url | http://irep.iium.edu.my/13252/ http://irep.iium.edu.my/13252/ http://irep.iium.edu.my/13252/1/oral_presentation_2011.pdf |