The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
The prevalence of diabetes in Malaysia within 10 years had doubled (Public Health Institute, 2008). The complication of the disease has more impact and burden on the health (ADA, 2008). The seriousness and the occurrence of the complications are closely related with tightly control hyperglycaemia (U...
| Main Authors: | , , , , |
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| Format: | Proceeding Paper |
| Language: | English |
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2010
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| Online Access: | http://irep.iium.edu.my/11407/ http://irep.iium.edu.my/11407/1/POSTERmspp2010.ppt |
| _version_ | 1848777324230606848 |
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| author | Kasmuri, Abdul Razak Mohd Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya |
| author_facet | Kasmuri, Abdul Razak Mohd Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya |
| author_sort | Kasmuri, Abdul Razak |
| building | IIUM Repository |
| collection | Online Access |
| description | The prevalence of diabetes in Malaysia within 10 years had doubled (Public Health Institute, 2008). The complication of the disease has more impact and burden on the health (ADA, 2008). The seriousness and the occurrence of the complications are closely related with tightly control hyperglycaemia (UKPDS,1998). Thus it is a better approach to screen substance that able to prevent postprandial hyperglycaemia that can cause fluctuating glucose levels i.e. to screen substance that able to decrease glucose absorption in GIT. Pithecellobium jiringa is already known to have antidiabetic property among Malaysians and used as its traditional remedy (Mohamed et al., 2005). A preliminary study showed that the plant has hypoglycaemic effect (Thevathasan, 1972). Radhiah et al. (2004) and Tungsarikarn et al. (2008) found that the plant has glucose lowering effect and the latter also proved the plant extract has an effect on alpha-glucosidase enzyme. On the other hand the seeds containing djenkolic acid which can cause djenkolism, which is a toxicity effect characterized by acute renal failure, urinary obstruction and spasmodic pain (Barceloux, 2009). The study was conducted with the aim at elaborating and reconciling the previous finding on the glucose lowering effect of P. jiringa. In order to make it more explorative, both of the seed and pericarp extracts of the plant were studied. |
| first_indexed | 2025-11-14T14:44:10Z |
| format | Proceeding Paper |
| id | iium-11407 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:44:10Z |
| publishDate | 2010 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-114072022-12-09T02:53:42Z http://irep.iium.edu.my/11407/ The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles Kasmuri, Abdul Razak Mohd Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya RM Therapeutics. Pharmacology The prevalence of diabetes in Malaysia within 10 years had doubled (Public Health Institute, 2008). The complication of the disease has more impact and burden on the health (ADA, 2008). The seriousness and the occurrence of the complications are closely related with tightly control hyperglycaemia (UKPDS,1998). Thus it is a better approach to screen substance that able to prevent postprandial hyperglycaemia that can cause fluctuating glucose levels i.e. to screen substance that able to decrease glucose absorption in GIT. Pithecellobium jiringa is already known to have antidiabetic property among Malaysians and used as its traditional remedy (Mohamed et al., 2005). A preliminary study showed that the plant has hypoglycaemic effect (Thevathasan, 1972). Radhiah et al. (2004) and Tungsarikarn et al. (2008) found that the plant has glucose lowering effect and the latter also proved the plant extract has an effect on alpha-glucosidase enzyme. On the other hand the seeds containing djenkolic acid which can cause djenkolism, which is a toxicity effect characterized by acute renal failure, urinary obstruction and spasmodic pain (Barceloux, 2009). The study was conducted with the aim at elaborating and reconciling the previous finding on the glucose lowering effect of P. jiringa. In order to make it more explorative, both of the seed and pericarp extracts of the plant were studied. 2010-06 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/11407/1/POSTERmspp2010.ppt Kasmuri, Abdul Razak and Mohd Hassan, Norazian and Arifin, Syamsul and Mehat, Isa and Mat Taib, Nurhaya (2010) The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles. In: Malaysian Society of Pharmacology and Physiology. |
| spellingShingle | RM Therapeutics. Pharmacology Kasmuri, Abdul Razak Mohd Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles |
| title | The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles |
| title_full | The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles |
| title_fullStr | The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles |
| title_full_unstemmed | The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles |
| title_short | The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles |
| title_sort | inhibition of glucose absorption of seed and pericarp extracts of pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles |
| topic | RM Therapeutics. Pharmacology |
| url | http://irep.iium.edu.my/11407/ http://irep.iium.edu.my/11407/1/POSTERmspp2010.ppt |