Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE)
The soluble receptor for advanced glycation end products, otherwise known as RAGE, is activated by a myriad of molecules, resulting in the progression of chronic diseases such as Alzheimer's disease, diabetes and cancer. This study genetically engineered bacterial and insect cells to produce va...
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| Format: | Thesis |
| Language: | English |
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Curtin University
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/995 |
| _version_ | 1848743547001372672 |
|---|---|
| author | Chandler, David James |
| author_facet | Chandler, David James |
| author_sort | Chandler, David James |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The soluble receptor for advanced glycation end products, otherwise known as RAGE, is activated by a myriad of molecules, resulting in the progression of chronic diseases such as Alzheimer's disease, diabetes and cancer. This study genetically engineered bacterial and insect cells to produce various forms of RAGE and the molecules that activate it. These proteins were purified, shown to be functional and now form a platform for research into the progression of these chronic diseases. |
| first_indexed | 2025-11-14T05:47:18Z |
| format | Thesis |
| id | curtin-20.500.11937-995 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:47:18Z |
| publishDate | 2014 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-9952017-02-20T06:40:16Z Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE) Chandler, David James The soluble receptor for advanced glycation end products, otherwise known as RAGE, is activated by a myriad of molecules, resulting in the progression of chronic diseases such as Alzheimer's disease, diabetes and cancer. This study genetically engineered bacterial and insect cells to produce various forms of RAGE and the molecules that activate it. These proteins were purified, shown to be functional and now form a platform for research into the progression of these chronic diseases. 2014 Thesis http://hdl.handle.net/20.500.11937/995 en Curtin University fulltext |
| spellingShingle | Chandler, David James Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE) |
| title | Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE) |
| title_full | Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE) |
| title_fullStr | Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE) |
| title_full_unstemmed | Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE) |
| title_short | Expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (sRAGE) |
| title_sort | expression, purification and characterisation of the recombinant soluble receptor for advanced glycosylation end products (srage) |
| url | http://hdl.handle.net/20.500.11937/995 |