The Role of Pigment Epithelium-derived Factor in Breast Cancer Cell Metabolism
The thesis investigates the potential of PEDF as a novel regulator of metabolism and metastasis in breast cancer. Findings highlight PEDF's critical role in modulating glucose metabolism, mitochondrial function, and metastatic progression, proposing it as a promising therapeutic target. Additio...
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| Format: | Thesis |
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Curtin University
2025
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| Online Access: | http://hdl.handle.net/20.500.11937/98030 |
| _version_ | 1848766351714287616 |
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| author | Abooshahab, Raziyeh |
| author_facet | Abooshahab, Raziyeh |
| author_sort | Abooshahab, Raziyeh |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The thesis investigates the potential of PEDF as a novel regulator of metabolism and metastasis in breast cancer. Findings highlight PEDF's critical role in modulating glucose metabolism, mitochondrial function, and metastatic progression, proposing it as a promising therapeutic target. Additionally, PEDF enhances chemotherapy effectiveness while mitigating drug resistance and side effects, underscoring its value for developing improved metabolism-based breast cancer therapies, pending further validation. |
| first_indexed | 2025-11-14T11:49:46Z |
| format | Thesis |
| id | curtin-20.500.11937-98030 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:49:46Z |
| publishDate | 2025 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-980302025-07-03T05:56:48Z The Role of Pigment Epithelium-derived Factor in Breast Cancer Cell Metabolism Abooshahab, Raziyeh The thesis investigates the potential of PEDF as a novel regulator of metabolism and metastasis in breast cancer. Findings highlight PEDF's critical role in modulating glucose metabolism, mitochondrial function, and metastatic progression, proposing it as a promising therapeutic target. Additionally, PEDF enhances chemotherapy effectiveness while mitigating drug resistance and side effects, underscoring its value for developing improved metabolism-based breast cancer therapies, pending further validation. 2025 Thesis http://hdl.handle.net/20.500.11937/98030 Curtin University fulltext |
| spellingShingle | Abooshahab, Raziyeh The Role of Pigment Epithelium-derived Factor in Breast Cancer Cell Metabolism |
| title | The Role of Pigment Epithelium-derived Factor in Breast
Cancer Cell Metabolism |
| title_full | The Role of Pigment Epithelium-derived Factor in Breast
Cancer Cell Metabolism |
| title_fullStr | The Role of Pigment Epithelium-derived Factor in Breast
Cancer Cell Metabolism |
| title_full_unstemmed | The Role of Pigment Epithelium-derived Factor in Breast
Cancer Cell Metabolism |
| title_short | The Role of Pigment Epithelium-derived Factor in Breast
Cancer Cell Metabolism |
| title_sort | role of pigment epithelium-derived factor in breast
cancer cell metabolism |
| url | http://hdl.handle.net/20.500.11937/98030 |