Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine

The enantioselectivity of the autocatalytic alkylation of 2-tert-butylpyrimidyl-5-carbaldehyde, initiated by chiral crystals of N-(2-thienylcarbonyl)glycine, is predicted computationally. The results are in accord with the correlation of the stereochemical outcome of the reaction and the absolute st...

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Main Authors: Carter, Damien, Rohl, Andrew, Shtukenberg, A., Bian, S., Hu, C., Baylon, L., Kahr, B., Mineki, H., Abe, K., Kawasaki, T., Soai, K.
Format: Journal Article
Published: American Chemical Society 2012
Online Access:http://pubs.acs.org/doi/abs/10.1021/cg300207d
http://hdl.handle.net/20.500.11937/9789
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author Carter, Damien
Rohl, Andrew
Shtukenberg, A.
Bian, S.
Hu, C.
Baylon, L.
Kahr, B.
Mineki, H.
Abe, K.
Kawasaki, T.
Soai, K.
author_facet Carter, Damien
Rohl, Andrew
Shtukenberg, A.
Bian, S.
Hu, C.
Baylon, L.
Kahr, B.
Mineki, H.
Abe, K.
Kawasaki, T.
Soai, K.
author_sort Carter, Damien
building Curtin Institutional Repository
collection Online Access
description The enantioselectivity of the autocatalytic alkylation of 2-tert-butylpyrimidyl-5-carbaldehyde, initiated by chiral crystals of N-(2-thienylcarbonyl)glycine, is predicted computationally. The results are in accord with the correlation of the stereochemical outcome of the reaction and the absolute structure of the crystals determined by the anomalous dispersion of X-rays and circular dichroism spectroscopy.
first_indexed 2025-11-14T06:27:06Z
format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T06:27:06Z
publishDate 2012
publisher American Chemical Society
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-97892019-02-19T05:35:29Z Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine Carter, Damien Rohl, Andrew Shtukenberg, A. Bian, S. Hu, C. Baylon, L. Kahr, B. Mineki, H. Abe, K. Kawasaki, T. Soai, K. The enantioselectivity of the autocatalytic alkylation of 2-tert-butylpyrimidyl-5-carbaldehyde, initiated by chiral crystals of N-(2-thienylcarbonyl)glycine, is predicted computationally. The results are in accord with the correlation of the stereochemical outcome of the reaction and the absolute structure of the crystals determined by the anomalous dispersion of X-rays and circular dichroism spectroscopy. 2012 Journal Article http://hdl.handle.net/20.500.11937/9789 http://pubs.acs.org/doi/abs/10.1021/cg300207d American Chemical Society restricted
spellingShingle Carter, Damien
Rohl, Andrew
Shtukenberg, A.
Bian, S.
Hu, C.
Baylon, L.
Kahr, B.
Mineki, H.
Abe, K.
Kawasaki, T.
Soai, K.
Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine
title Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine
title_full Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine
title_fullStr Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine
title_full_unstemmed Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine
title_short Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine
title_sort prediction of soai reaction enantioselectivity induced by crystals of n-(2-thienylcarbonyl)glycine
url http://pubs.acs.org/doi/abs/10.1021/cg300207d
http://hdl.handle.net/20.500.11937/9789