Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic.
Alzheimer’s Disease and Type 2 Diabetes share many common features, one of which is insulin resistance. This thesis explores how changes in insulin sensitivity and glucose metabolism impact brain function and Alzheimer??s biomarkers and assesses the benefits of anti-diabetic medications in the brain...
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| Format: | Thesis |
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Curtin University
2024
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| Online Access: | http://hdl.handle.net/20.500.11937/97821 |
| _version_ | 1848766324602306560 |
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| author | Woodfield, Amy Marie |
| author_facet | Woodfield, Amy Marie |
| author_sort | Woodfield, Amy Marie |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Alzheimer’s Disease and Type 2 Diabetes share many common features, one of which is insulin resistance. This thesis explores how changes in insulin sensitivity and glucose metabolism impact brain function and Alzheimer??s biomarkers and assesses the benefits of anti-diabetic medications in the brain. Together, this provides insight into how peripheral changes in insulin sensitivity and glucose metabolism impact the brain and presents novel findings with an insulin-mimetic indicating potential modulation of the processing of amyloid-beta. |
| first_indexed | 2025-11-14T11:49:20Z |
| format | Thesis |
| id | curtin-20.500.11937-97821 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:49:20Z |
| publishDate | 2024 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-978212025-05-29T04:38:39Z Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic. Woodfield, Amy Marie Alzheimer’s Disease and Type 2 Diabetes share many common features, one of which is insulin resistance. This thesis explores how changes in insulin sensitivity and glucose metabolism impact brain function and Alzheimer??s biomarkers and assesses the benefits of anti-diabetic medications in the brain. Together, this provides insight into how peripheral changes in insulin sensitivity and glucose metabolism impact the brain and presents novel findings with an insulin-mimetic indicating potential modulation of the processing of amyloid-beta. 2024 Thesis http://hdl.handle.net/20.500.11937/97821 Curtin University fulltext |
| spellingShingle | Woodfield, Amy Marie Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic. |
| title | Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic. |
| title_full | Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic. |
| title_fullStr | Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic. |
| title_full_unstemmed | Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic. |
| title_short | Investigating the Relationships Between Insulin Resistance, Cognitive Function and Alzheimer’s Disease Biomarkers and Exploring the Potential Benefits of an Insulin Mimetic. |
| title_sort | investigating the relationships between insulin resistance, cognitive function and alzheimer’s disease biomarkers and exploring the potential benefits of an insulin mimetic. |
| url | http://hdl.handle.net/20.500.11937/97821 |