Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis
Objective: To estimate full hepatitis B vaccination coverage (uptake of ≥3 doses of vaccine) among health-care workers (HCWs) in Africa. Methods: We systematically searched the PubMed® Embase® CINAHL and Psych-Info databases for studies published from January 2010 to October 2017 that reported full...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Language: | English |
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2018
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| Online Access: | http://hdl.handle.net/20.500.11937/97789 |
| _version_ | 1848766316555534336 |
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| author | Auta, A. Adewuyi, Emmanuel Kureh, G.T. Onoviran, N. Adeloye, D. |
| author_facet | Auta, A. Adewuyi, Emmanuel Kureh, G.T. Onoviran, N. Adeloye, D. |
| author_sort | Auta, A. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objective: To estimate full hepatitis B vaccination coverage (uptake of ≥3 doses of vaccine) among health-care workers (HCWs) in Africa. Methods: We systematically searched the PubMed® Embase® CINAHL and Psych-Info databases for studies published from January 2010 to October 2017 that reported full hepatitis B vaccination coverage among HCWs in Africa. A random effects meta-analysis was conducted to determine pooled estimates of full vaccination coverage. Results: Of the 331 articles identified, 35 studies from 15 African countries met the inclusion criteria and were included in the review. The estimated full hepatitis B vaccination coverage was 24.7% (95% CI: 17.3–32.0). Regional coverage was highest in northern Africa (62.1%, 95% CI: 42.5–81.7) and lowest in central Africa (13.4%, 95% CI: 4.5–22.3). Doctors were more likely (OR: 2.6, 95% CI: 1.8–3.7) to be fully vaccinated than Nurses with estimated pooled estimates of 52.4% (95% CI: 31.1–73.8) and 26.3% (95% CI: 9.7–42.9), respectively. Also, HCWs with 10 or more years of experience were more likely to be vaccinated than those with less than 10 years of experience (OR: 2.2, 95% CI: 1.5–3.3). The common reasons identified for non-vaccination of HCWs were unavailability of vaccine 50.5% (95% CI: 26.5–74.4), busy work schedule 37.5% (95% CI: 12.6–62.4) and cost of vaccination 18.4% (95% CI: 7.1–29.7). Conclusion: The evidence available suggests that many HCWs in Africa are at risk of Hepatitis B infection as only a quarter of them were fully vaccinated against Hepatitis B virus. This study highlights the need for all African governments to establish and implement hepatitis B vaccination policies for HCWs. |
| first_indexed | 2025-11-14T11:49:13Z |
| format | Journal Article |
| id | curtin-20.500.11937-97789 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | eng |
| last_indexed | 2025-11-14T11:49:13Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-977892025-05-22T15:28:11Z Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis Auta, A. Adewuyi, Emmanuel Kureh, G.T. Onoviran, N. Adeloye, D. Africa Healthcare workers Hepatitis B Occupational exposure Vaccination Africa Female Health Personnel Hepatitis B Vaccines Humans Male Occupational Exposure Vaccination Humans Hepatitis B Vaccines Vaccination Occupational Exposure Health Personnel Africa Female Male Objective: To estimate full hepatitis B vaccination coverage (uptake of ≥3 doses of vaccine) among health-care workers (HCWs) in Africa. Methods: We systematically searched the PubMed® Embase® CINAHL and Psych-Info databases for studies published from January 2010 to October 2017 that reported full hepatitis B vaccination coverage among HCWs in Africa. A random effects meta-analysis was conducted to determine pooled estimates of full vaccination coverage. Results: Of the 331 articles identified, 35 studies from 15 African countries met the inclusion criteria and were included in the review. The estimated full hepatitis B vaccination coverage was 24.7% (95% CI: 17.3–32.0). Regional coverage was highest in northern Africa (62.1%, 95% CI: 42.5–81.7) and lowest in central Africa (13.4%, 95% CI: 4.5–22.3). Doctors were more likely (OR: 2.6, 95% CI: 1.8–3.7) to be fully vaccinated than Nurses with estimated pooled estimates of 52.4% (95% CI: 31.1–73.8) and 26.3% (95% CI: 9.7–42.9), respectively. Also, HCWs with 10 or more years of experience were more likely to be vaccinated than those with less than 10 years of experience (OR: 2.2, 95% CI: 1.5–3.3). The common reasons identified for non-vaccination of HCWs were unavailability of vaccine 50.5% (95% CI: 26.5–74.4), busy work schedule 37.5% (95% CI: 12.6–62.4) and cost of vaccination 18.4% (95% CI: 7.1–29.7). Conclusion: The evidence available suggests that many HCWs in Africa are at risk of Hepatitis B infection as only a quarter of them were fully vaccinated against Hepatitis B virus. This study highlights the need for all African governments to establish and implement hepatitis B vaccination policies for HCWs. 2018 Journal Article http://hdl.handle.net/20.500.11937/97789 10.1016/j.vaccine.2018.06.043 eng unknown |
| spellingShingle | Africa Healthcare workers Hepatitis B Occupational exposure Vaccination Africa Female Health Personnel Hepatitis B Vaccines Humans Male Occupational Exposure Vaccination Humans Hepatitis B Vaccines Vaccination Occupational Exposure Health Personnel Africa Female Male Auta, A. Adewuyi, Emmanuel Kureh, G.T. Onoviran, N. Adeloye, D. Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis |
| title | Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis |
| title_full | Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis |
| title_fullStr | Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis |
| title_full_unstemmed | Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis |
| title_short | Hepatitis B vaccination coverage among health-care workers in Africa: A systematic review and meta-analysis |
| title_sort | hepatitis b vaccination coverage among health-care workers in africa: a systematic review and meta-analysis |
| topic | Africa Healthcare workers Hepatitis B Occupational exposure Vaccination Africa Female Health Personnel Hepatitis B Vaccines Humans Male Occupational Exposure Vaccination Humans Hepatitis B Vaccines Vaccination Occupational Exposure Health Personnel Africa Female Male |
| url | http://hdl.handle.net/20.500.11937/97789 |