Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study
Introduction: There are limited data on chest computed tomography (CT) findings in the assessment of lung nodules among adult Aboriginal Australians. In this retrospective study, we assessed lung nodules among a group of adult Aboriginal Australians in the Northern Territory of Australia. Methods: P...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Language: | English |
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2024
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| Online Access: | http://hdl.handle.net/20.500.11937/97701 |
| _version_ | 1848766307171827712 |
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| author | Ng, L.Y. Howarth, T.P. Doss, Arockia Charakidis, M. Karanth, N.V. Mo, L. Heraganahally, S.S. |
| author_facet | Ng, L.Y. Howarth, T.P. Doss, Arockia Charakidis, M. Karanth, N.V. Mo, L. Heraganahally, S.S. |
| author_sort | Ng, L.Y. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Introduction: There are limited data on chest computed tomography (CT) findings in the assessment of lung nodules among adult Aboriginal Australians. In this retrospective study, we assessed lung nodules among a group of adult Aboriginal Australians in the Northern Territory of Australia. Methods: Patients who underwent at least two chest CT scans between 2012 and 2020 among those referred to undergo lung function testing (spirometry) were included. Chest CT scans were assessed for the number, location, size and morphological characteristics of lung nodules. Results: Of the 402 chest CTs assessed, 75 patients (18.7%) had lung nodules, and 57 patients were included in the final analysis with at least two CT scans available for assessment over a median follow-up of 87 weeks. Most patients (68%) were women, with a median age of 58 years and smoking history in 83%. The majority recorded only a single nodule 43 (74%). Six patients (10%) were diagnosed with malignancy, five with primary lung cancer and one with metastatic thyroid cancer. Of the 51 (90%) patients assessed to be benign, 64 nodules were identified, of which 25 (39%) resolved, 38 (59%) remained stable and one (1.8%) enlarged on follow-up. Nodules among patients with malignancy were typically initially larger and enlarged over time, had spiculated margins and were solid, showing no specific lobar predilection. Conclusions: Most lung nodules in Aboriginal Australians are likely to be benign. However, a proportion could be malignant. Further prospective studies are required for prognostication and monitoring of lung nodules in this population. |
| first_indexed | 2025-11-14T11:49:04Z |
| format | Journal Article |
| id | curtin-20.500.11937-97701 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | eng |
| last_indexed | 2025-11-14T11:49:04Z |
| publishDate | 2024 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-977012025-05-08T17:52:42Z Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study Ng, L.Y. Howarth, T.P. Doss, Arockia Charakidis, M. Karanth, N.V. Mo, L. Heraganahally, S.S. First Nations Indigenous lung cancer malignancy pulmonary radiology respiratory Adult Aged Female Humans Male Middle Aged Australia Australian Aboriginal and Torres Strait Islander Peoples Lung Neoplasms Retrospective Studies Tomography, X-Ray Computed Humans Lung Neoplasms Tomography, X-Ray Computed Retrospective Studies Adult Aged Middle Aged Australia Female Male Australian Aboriginal and Torres Strait Islander Peoples Introduction: There are limited data on chest computed tomography (CT) findings in the assessment of lung nodules among adult Aboriginal Australians. In this retrospective study, we assessed lung nodules among a group of adult Aboriginal Australians in the Northern Territory of Australia. Methods: Patients who underwent at least two chest CT scans between 2012 and 2020 among those referred to undergo lung function testing (spirometry) were included. Chest CT scans were assessed for the number, location, size and morphological characteristics of lung nodules. Results: Of the 402 chest CTs assessed, 75 patients (18.7%) had lung nodules, and 57 patients were included in the final analysis with at least two CT scans available for assessment over a median follow-up of 87 weeks. Most patients (68%) were women, with a median age of 58 years and smoking history in 83%. The majority recorded only a single nodule 43 (74%). Six patients (10%) were diagnosed with malignancy, five with primary lung cancer and one with metastatic thyroid cancer. Of the 51 (90%) patients assessed to be benign, 64 nodules were identified, of which 25 (39%) resolved, 38 (59%) remained stable and one (1.8%) enlarged on follow-up. Nodules among patients with malignancy were typically initially larger and enlarged over time, had spiculated margins and were solid, showing no specific lobar predilection. Conclusions: Most lung nodules in Aboriginal Australians are likely to be benign. However, a proportion could be malignant. Further prospective studies are required for prognostication and monitoring of lung nodules in this population. 2024 Journal Article http://hdl.handle.net/20.500.11937/97701 10.1002/jmrs.783 eng unknown |
| spellingShingle | First Nations Indigenous lung cancer malignancy pulmonary radiology respiratory Adult Aged Female Humans Male Middle Aged Australia Australian Aboriginal and Torres Strait Islander Peoples Lung Neoplasms Retrospective Studies Tomography, X-Ray Computed Humans Lung Neoplasms Tomography, X-Ray Computed Retrospective Studies Adult Aged Middle Aged Australia Female Male Australian Aboriginal and Torres Strait Islander Peoples Ng, L.Y. Howarth, T.P. Doss, Arockia Charakidis, M. Karanth, N.V. Mo, L. Heraganahally, S.S. Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study |
| title | Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study |
| title_full | Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study |
| title_fullStr | Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study |
| title_full_unstemmed | Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study |
| title_short | Significance of lung nodules detected on chest CT among adult Aboriginal Australians – a retrospective descriptive study |
| title_sort | significance of lung nodules detected on chest ct among adult aboriginal australians – a retrospective descriptive study |
| topic | First Nations Indigenous lung cancer malignancy pulmonary radiology respiratory Adult Aged Female Humans Male Middle Aged Australia Australian Aboriginal and Torres Strait Islander Peoples Lung Neoplasms Retrospective Studies Tomography, X-Ray Computed Humans Lung Neoplasms Tomography, X-Ray Computed Retrospective Studies Adult Aged Middle Aged Australia Female Male Australian Aboriginal and Torres Strait Islander Peoples |
| url | http://hdl.handle.net/20.500.11937/97701 |