The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse
We have localized the spinocerebellar neuron groups in C57BL/6J mice by injecting the retrograde neuronal tracer Fluoro-Gold into the cerebellum and examined the distribution of SMI 32 and the calcium-binding proteins (CBPs), calbindin-D-28K (Cb), calretinin (Cr), and parvalbumin (Pv) in the spinal...
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| Format: | Journal Article |
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Elsevier
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/9729 |
| _version_ | 1848746033539973120 |
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| author | Fu, Y. Sengul, G. Paxinos, G. Watson, Charles |
| author_facet | Fu, Y. Sengul, G. Paxinos, G. Watson, Charles |
| author_sort | Fu, Y. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | We have localized the spinocerebellar neuron groups in C57BL/6J mice by injecting the retrograde neuronal tracer Fluoro-Gold into the cerebellum and examined the distribution of SMI 32 and the calcium-binding proteins (CBPs), calbindin-D-28K (Cb), calretinin (Cr), and parvalbumin (Pv) in the spinal precerebellar nuclei. The spinal precerebellar neuron clusters identified were the dorsal nucleus, central cervical nucleus, lumbar border precerebellar nucleus, lumbar precerebellar nucleus, and sacral precerebellar nucleus. Some dispersed neurons in the deep dorsal horn and spinal laminae 6–8 also projected to the cerebellum. Cb, Cr, Pv, and SMI 32 were present in all major spinal precerebellar nuclei and Pv was the most commonly observed CBP. A number of genes expressed in hindbrain precerebellar nuclei are also expressed in spinal precerebellar groups, but there were some differences in gene expression profile between the different spinal precerebellar nuclei, pointing to functional diversity amongst them. |
| first_indexed | 2025-11-14T06:26:49Z |
| format | Journal Article |
| id | curtin-20.500.11937-9729 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:26:49Z |
| publishDate | 2012 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-97292019-02-19T05:35:29Z The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse Fu, Y. Sengul, G. Paxinos, G. Watson, Charles Calcium binding proteins Genes Precerebellar nucleus SMI 32 Spinal cord We have localized the spinocerebellar neuron groups in C57BL/6J mice by injecting the retrograde neuronal tracer Fluoro-Gold into the cerebellum and examined the distribution of SMI 32 and the calcium-binding proteins (CBPs), calbindin-D-28K (Cb), calretinin (Cr), and parvalbumin (Pv) in the spinal precerebellar nuclei. The spinal precerebellar neuron clusters identified were the dorsal nucleus, central cervical nucleus, lumbar border precerebellar nucleus, lumbar precerebellar nucleus, and sacral precerebellar nucleus. Some dispersed neurons in the deep dorsal horn and spinal laminae 6–8 also projected to the cerebellum. Cb, Cr, Pv, and SMI 32 were present in all major spinal precerebellar nuclei and Pv was the most commonly observed CBP. A number of genes expressed in hindbrain precerebellar nuclei are also expressed in spinal precerebellar groups, but there were some differences in gene expression profile between the different spinal precerebellar nuclei, pointing to functional diversity amongst them. 2012 Journal Article http://hdl.handle.net/20.500.11937/9729 10.1016/j.neulet.2012.05.002 Elsevier fulltext |
| spellingShingle | Calcium binding proteins Genes Precerebellar nucleus SMI 32 Spinal cord Fu, Y. Sengul, G. Paxinos, G. Watson, Charles The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse |
| title | The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse |
| title_full | The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse |
| title_fullStr | The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse |
| title_full_unstemmed | The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse |
| title_short | The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse |
| title_sort | spinal precerebellar nuclei: calcium binding proteins and gene expression profile in the mouse |
| topic | Calcium binding proteins Genes Precerebellar nucleus SMI 32 Spinal cord |
| url | http://hdl.handle.net/20.500.11937/9729 |