What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions
Background: Integrated data repositories (IDRs), also referred to as clinical data warehouses, are platforms used for the integration of several data sources through specialized analytical tools that facilitate data processing and analysis. IDRs offer several opportunities for clinical data reuse, a...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Language: | English |
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2020
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| Online Access: | http://hdl.handle.net/20.500.11937/96871 |
| _version_ | 1848766202829078528 |
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| author | Gagalova, Kristina Angelica Leon Elizalde, M. Portales-Casamar, E. Görges, M. |
| author_facet | Gagalova, Kristina Angelica Leon Elizalde, M. Portales-Casamar, E. Görges, M. |
| author_sort | Gagalova, Kristina |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Integrated data repositories (IDRs), also referred to as clinical data warehouses, are platforms used for the integration of several data sources through specialized analytical tools that facilitate data processing and analysis. IDRs offer several opportunities for clinical data reuse, and the number of institutions implementing an IDR has grown steadily in the past decade. Objective: The architectural choices of major IDRs are highly diverse and determining their differences can be overwhelming. This review aims to explore the underlying models and common features of IDRs, provide a high-level overview for those entering the field, and propose a set of guiding principles for small- to medium-sized health institutions embarking on IDR implementation. Methods: We reviewed manuscripts published in peer-reviewed scientific literature between 2008 and 2020, and selected those that specifically describe IDR architectures. Of 255 shortlisted articles, we found 34 articles describing 29 different architectures. The different IDRs were analyzed for common features and classified according to their data processing and integration solution choices. Results: Despite common trends in the selection of standard terminologies and data models, the IDRs examined showed heterogeneity in the underlying architecture design. We identified 4 common architecture models that use different approaches for data processing and integration. These different approaches were driven by a variety of features such as data sources, whether the IDR was for a single institution or a collaborative project, the intended primary data user, and purpose (research-only or including clinical or operational decision making). Conclusions: IDR implementations are diverse and complex undertakings, which benefit from being preceded by an evaluation of requirements and definition of scope in the early planning stage. Factors such as data source diversity and intended users of the IDR influence data flow and synchronization, both of which are crucial factors in IDR architecture planning. |
| first_indexed | 2025-11-14T11:47:24Z |
| format | Journal Article |
| id | curtin-20.500.11937-96871 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | eng |
| last_indexed | 2025-11-14T11:47:24Z |
| publishDate | 2020 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-968712025-02-13T00:34:57Z What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions Gagalova, Kristina Angelica Leon Elizalde, M. Portales-Casamar, E. Görges, M. data aggregation data analytics data warehousing database health informatics information storage and retrieval Background: Integrated data repositories (IDRs), also referred to as clinical data warehouses, are platforms used for the integration of several data sources through specialized analytical tools that facilitate data processing and analysis. IDRs offer several opportunities for clinical data reuse, and the number of institutions implementing an IDR has grown steadily in the past decade. Objective: The architectural choices of major IDRs are highly diverse and determining their differences can be overwhelming. This review aims to explore the underlying models and common features of IDRs, provide a high-level overview for those entering the field, and propose a set of guiding principles for small- to medium-sized health institutions embarking on IDR implementation. Methods: We reviewed manuscripts published in peer-reviewed scientific literature between 2008 and 2020, and selected those that specifically describe IDR architectures. Of 255 shortlisted articles, we found 34 articles describing 29 different architectures. The different IDRs were analyzed for common features and classified according to their data processing and integration solution choices. Results: Despite common trends in the selection of standard terminologies and data models, the IDRs examined showed heterogeneity in the underlying architecture design. We identified 4 common architecture models that use different approaches for data processing and integration. These different approaches were driven by a variety of features such as data sources, whether the IDR was for a single institution or a collaborative project, the intended primary data user, and purpose (research-only or including clinical or operational decision making). Conclusions: IDR implementations are diverse and complex undertakings, which benefit from being preceded by an evaluation of requirements and definition of scope in the early planning stage. Factors such as data source diversity and intended users of the IDR influence data flow and synchronization, both of which are crucial factors in IDR architecture planning. 2020 Journal Article http://hdl.handle.net/20.500.11937/96871 10.2196/17687 eng http://creativecommons.org/licenses/by/4.0/ fulltext |
| spellingShingle | data aggregation data analytics data warehousing database health informatics information storage and retrieval Gagalova, Kristina Angelica Leon Elizalde, M. Portales-Casamar, E. Görges, M. What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions |
| title | What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions |
| title_full | What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions |
| title_fullStr | What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions |
| title_full_unstemmed | What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions |
| title_short | What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions |
| title_sort | what you need to know before implementing a clinical research data warehouse: comparative review of integrated data repositories in health care institutions |
| topic | data aggregation data analytics data warehousing database health informatics information storage and retrieval |
| url | http://hdl.handle.net/20.500.11937/96871 |