RNA-Scoop: interactive visualization of transcripts in single-cell transcriptomes

RNA-Scoop: interactive visualization of transcripts in single-cell transcriptomes

Recent advances in single-cell RNA sequencing technologies have made detection of transcripts in single cells possible. The level of resolution provided by these technologies can be used to study changes in transcript usage across cell populations and help investigate new biology. Here, we introduce...

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Bibliographic Details
Main Authors: Stephenson, M., Nip, K.M., Hafezqorani, S., Gagalova, Kristina, Yang, C., Warren, R.L., Birol, I.
Format: Journal Article
Language:English
Published: Oxford University Press 2021
Online Access:http://hdl.handle.net/20.500.11937/96870
Description
Summary:Recent advances in single-cell RNA sequencing technologies have made detection of transcripts in single cells possible. The level of resolution provided by these technologies can be used to study changes in transcript usage across cell populations and help investigate new biology. Here, we introduce RNA-Scoop, an interactive cell cluster and transcriptome visualization tool to analyze transcript usage across cell categories and clusters. The tool allows users to examine differential transcript expression across clusters and investigate how usage of specific transcript expression mechanisms varies across cell groups.

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