Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial

Aims The aims of this feasibility trial were to assess the acceptability and feasibility of peer-led recovery groups for people with psychosis in a low-resource South African setting, to assess the feasibility of trial methods, and to determine key parameters in preparation for a definitive trial. M...

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Main Authors: Asher, L., Rapiya, B., Repper, J., Reddy, T., Myers, Bronwyn, Faris, G., Petersen, I., Hanlon, C., Brooke-Sumner, C.
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/96592
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author Asher, L.
Rapiya, B.
Repper, J.
Reddy, T.
Myers, Bronwyn
Faris, G.
Petersen, I.
Hanlon, C.
Brooke-Sumner, C.
author_facet Asher, L.
Rapiya, B.
Repper, J.
Reddy, T.
Myers, Bronwyn
Faris, G.
Petersen, I.
Hanlon, C.
Brooke-Sumner, C.
author_sort Asher, L.
building Curtin Institutional Repository
collection Online Access
description Aims The aims of this feasibility trial were to assess the acceptability and feasibility of peer-led recovery groups for people with psychosis in a low-resource South African setting, to assess the feasibility of trial methods, and to determine key parameters in preparation for a definitive trial. Methods The design was an individually randomised feasibility trial comparing recovery groups in addition to treatment as usual (TAU) with TAU alone. Ninety-two isiXhosa-speaking people with psychosis and forty-seven linked caregivers were recruited from primary care clinics and randomly allocated to trial arms in a 1:1 allocation ratio. TAU comprised anti-psychotic medication delivered in primary care. The intervention arm comprised six recovery groups including service users and caregivers. Two-hour recovery group sessions were delivered weekly in a 2-month auxiliary social worker (ASW)-led phase, then a 3-month peer-led phase. To explore acceptability and feasibility, a mixed methods process evaluation included 25 in-depth interviews and 2 focus group discussions at 5months with service users, caregivers and implementers, and quantitative data collection including attendance and facilitator competence. To explore potential effectiveness, quantitative outcome data (functioning, relapse, unmet needs, personal recovery, stigma, health service use, medication adherence and caregiver burden) were collected at baseline, 2months and 5months post randomisation. Trial registration: PACTR202202482587686. Results Qualitative interviews revealed that recovery groups were broadly acceptable with most participants finding groups to be an enjoyable opportunity for social interaction, and joint problem-solving. Peer facilitation was a positive experience; however a minority of participants did not value expertise by lived experience to the same degree as expertise of professional facilitators. Attendance was moderate in the ASW-led phase (participants attended 59% sessions on average) and decreased in the peer-led phase (41% on average). Participants desired a greater focus on productive activities and financial security. Recovery groups appeared to positively impact on relapse. Relapse occurred in 1 (2.2%) of 46 participants in the recovery group arm compared to 8 (17.4%) of 46 participants in the control arm (risk difference -0.15 [95% CI: -0.26; -0.05]). Recovery groups also impacted on the number of days in the last month totally unable to work (mean 1.4days recovery groups vs 7.7days control; adjusted mean difference -6.3 [95%CI: -12.2; -0.3]). There were no effects on other outcomes. Conclusion Peer-led recovery groups for people with psychosis in South Africa are potentially acceptable, feasible and effective. A larger trial, incorporating amendments such as increased support for peer facilitators, is needed to demonstrate intervention effectiveness definitively.
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spelling curtin-20.500.11937-965922025-01-24T04:07:03Z Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial Asher, L. Rapiya, B. Repper, J. Reddy, T. Myers, Bronwyn Faris, G. Petersen, I. Hanlon, C. Brooke-Sumner, C. Psychosis community mental healthcare peer support personal recovery psychosocial intervention Humans Feasibility Studies Psychotic Disorders Peer Group South Africa Male Female Adult Caregivers Middle Aged Antipsychotic Agents Humans Antipsychotic Agents Feasibility Studies Peer Group Psychotic Disorders Adult Middle Aged Caregivers South Africa Female Male Aims The aims of this feasibility trial were to assess the acceptability and feasibility of peer-led recovery groups for people with psychosis in a low-resource South African setting, to assess the feasibility of trial methods, and to determine key parameters in preparation for a definitive trial. Methods The design was an individually randomised feasibility trial comparing recovery groups in addition to treatment as usual (TAU) with TAU alone. Ninety-two isiXhosa-speaking people with psychosis and forty-seven linked caregivers were recruited from primary care clinics and randomly allocated to trial arms in a 1:1 allocation ratio. TAU comprised anti-psychotic medication delivered in primary care. The intervention arm comprised six recovery groups including service users and caregivers. Two-hour recovery group sessions were delivered weekly in a 2-month auxiliary social worker (ASW)-led phase, then a 3-month peer-led phase. To explore acceptability and feasibility, a mixed methods process evaluation included 25 in-depth interviews and 2 focus group discussions at 5months with service users, caregivers and implementers, and quantitative data collection including attendance and facilitator competence. To explore potential effectiveness, quantitative outcome data (functioning, relapse, unmet needs, personal recovery, stigma, health service use, medication adherence and caregiver burden) were collected at baseline, 2months and 5months post randomisation. Trial registration: PACTR202202482587686. Results Qualitative interviews revealed that recovery groups were broadly acceptable with most participants finding groups to be an enjoyable opportunity for social interaction, and joint problem-solving. Peer facilitation was a positive experience; however a minority of participants did not value expertise by lived experience to the same degree as expertise of professional facilitators. Attendance was moderate in the ASW-led phase (participants attended 59% sessions on average) and decreased in the peer-led phase (41% on average). Participants desired a greater focus on productive activities and financial security. Recovery groups appeared to positively impact on relapse. Relapse occurred in 1 (2.2%) of 46 participants in the recovery group arm compared to 8 (17.4%) of 46 participants in the control arm (risk difference -0.15 [95% CI: -0.26; -0.05]). Recovery groups also impacted on the number of days in the last month totally unable to work (mean 1.4days recovery groups vs 7.7days control; adjusted mean difference -6.3 [95%CI: -12.2; -0.3]). There were no effects on other outcomes. Conclusion Peer-led recovery groups for people with psychosis in South Africa are potentially acceptable, feasible and effective. A larger trial, incorporating amendments such as increased support for peer facilitators, is needed to demonstrate intervention effectiveness definitively. 2024 Journal Article http://hdl.handle.net/20.500.11937/96592 10.1017/S2045796024000556 eng http://creativecommons.org/licenses/by/4.0 fulltext
spellingShingle Psychosis
community mental healthcare
peer support
personal recovery
psychosocial intervention
Humans
Feasibility Studies
Psychotic Disorders
Peer Group
South Africa
Male
Female
Adult
Caregivers
Middle Aged
Antipsychotic Agents
Humans
Antipsychotic Agents
Feasibility Studies
Peer Group
Psychotic Disorders
Adult
Middle Aged
Caregivers
South Africa
Female
Male
Asher, L.
Rapiya, B.
Repper, J.
Reddy, T.
Myers, Bronwyn
Faris, G.
Petersen, I.
Hanlon, C.
Brooke-Sumner, C.
Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial
title Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial
title_full Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial
title_fullStr Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial
title_full_unstemmed Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial
title_short Peer-led recovery groups for people with psychosis in South Africa (PRIZE): Results of a randomized controlled feasibility trial
title_sort peer-led recovery groups for people with psychosis in south africa (prize): results of a randomized controlled feasibility trial
topic Psychosis
community mental healthcare
peer support
personal recovery
psychosocial intervention
Humans
Feasibility Studies
Psychotic Disorders
Peer Group
South Africa
Male
Female
Adult
Caregivers
Middle Aged
Antipsychotic Agents
Humans
Antipsychotic Agents
Feasibility Studies
Peer Group
Psychotic Disorders
Adult
Middle Aged
Caregivers
South Africa
Female
Male
url http://hdl.handle.net/20.500.11937/96592