Evidence for an ancient aquatic origin of the RNA viral order Articulavirales
The emergence of previously unknown disease-causing viruses in mammals is in part the result of a long-term evolutionary process. Reconstructing the deep phylogenetic histories of viruses helps identify major evolutionary transitions and contextualizes the emergence of viruses in new hosts. We used...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Language: | English |
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2023
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| Online Access: | http://purl.org/au-research/grants/arc/LP160101508 http://hdl.handle.net/20.500.11937/96165 |
| _version_ | 1848766104690753536 |
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| author | Petrone, M.E. Parry, R. Mifsud, J.C.O. Van Brussel, K. Vorhees, I. Richards, Zoe Holmes, E.C. |
| author_facet | Petrone, M.E. Parry, R. Mifsud, J.C.O. Van Brussel, K. Vorhees, I. Richards, Zoe Holmes, E.C. |
| author_sort | Petrone, M.E. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The emergence of previously unknown disease-causing viruses in mammals is in part the result of a long-term evolutionary process. Reconstructing the deep phylogenetic histories of viruses helps identify major evolutionary transitions and contextualizes the emergence of viruses in new hosts. We used a combination of total RNA sequencing and transcriptome data mining to extend the diversity and evolutionary history of the RNA virus order Articulavirales, which includes the influenza viruses. We identified instances of Articulavirales in the invertebrate phylum Cnidaria (including corals), constituting a novel and divergent family that we provisionally named the “Cnidenomoviridae.” We further extended the evolutionary history of the influenza virus lineage by identifying four divergent, fish-associated influenza-like viruses, thereby supporting the hypothesis that fish were among the first hosts of influenza viruses. In addition, we substantially expanded the phylogenetic diversity of quaranjaviruses and proposed that this genus be reclassified as a family—the “Quaranjaviridae.” Within this putative family, we identified a novel arachnid-infecting genus, provisionally named “Cheliceravirus.” Notably, we observed a close phylogenetic relationship between the Crustacea- and Chelicerata-infecting “Quaranjaviridae” that is inconsistent with virus–host codivergence. Together, these data suggest that the Articulavirales has evolved over at least 600 million years, first emerging in aquatic animals. Importantly, the evolution of the Articulavirales was likely shaped by multiple aquatic–terrestrial transitions and substantial host jumps, some of which are still observable today. |
| first_indexed | 2025-11-14T11:45:51Z |
| format | Journal Article |
| id | curtin-20.500.11937-96165 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | eng |
| last_indexed | 2025-11-14T11:45:51Z |
| publishDate | 2023 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-961652024-11-07T23:35:03Z Evidence for an ancient aquatic origin of the RNA viral order Articulavirales Petrone, M.E. Parry, R. Mifsud, J.C.O. Van Brussel, K. Vorhees, I. Richards, Zoe Holmes, E.C. Articulavirales Cnidaria evolution influenza virosphere Animals Humans Phylogeny RNA Viruses Influenza, Human Invertebrates Orthomyxoviridae RNA Evolution, Molecular RNA, Viral Mammals Animals Mammals Humans Invertebrates RNA Viruses Orthomyxoviridae RNA RNA, Viral Evolution, Molecular Phylogeny Influenza, Human The emergence of previously unknown disease-causing viruses in mammals is in part the result of a long-term evolutionary process. Reconstructing the deep phylogenetic histories of viruses helps identify major evolutionary transitions and contextualizes the emergence of viruses in new hosts. We used a combination of total RNA sequencing and transcriptome data mining to extend the diversity and evolutionary history of the RNA virus order Articulavirales, which includes the influenza viruses. We identified instances of Articulavirales in the invertebrate phylum Cnidaria (including corals), constituting a novel and divergent family that we provisionally named the “Cnidenomoviridae.” We further extended the evolutionary history of the influenza virus lineage by identifying four divergent, fish-associated influenza-like viruses, thereby supporting the hypothesis that fish were among the first hosts of influenza viruses. In addition, we substantially expanded the phylogenetic diversity of quaranjaviruses and proposed that this genus be reclassified as a family—the “Quaranjaviridae.” Within this putative family, we identified a novel arachnid-infecting genus, provisionally named “Cheliceravirus.” Notably, we observed a close phylogenetic relationship between the Crustacea- and Chelicerata-infecting “Quaranjaviridae” that is inconsistent with virus–host codivergence. Together, these data suggest that the Articulavirales has evolved over at least 600 million years, first emerging in aquatic animals. Importantly, the evolution of the Articulavirales was likely shaped by multiple aquatic–terrestrial transitions and substantial host jumps, some of which are still observable today. 2023 Journal Article http://hdl.handle.net/20.500.11937/96165 10.1073/pnas.2310529120 eng http://purl.org/au-research/grants/arc/LP160101508 https://creativecommons.org/licenses/by/4.0/ fulltext |
| spellingShingle | Articulavirales Cnidaria evolution influenza virosphere Animals Humans Phylogeny RNA Viruses Influenza, Human Invertebrates Orthomyxoviridae RNA Evolution, Molecular RNA, Viral Mammals Animals Mammals Humans Invertebrates RNA Viruses Orthomyxoviridae RNA RNA, Viral Evolution, Molecular Phylogeny Influenza, Human Petrone, M.E. Parry, R. Mifsud, J.C.O. Van Brussel, K. Vorhees, I. Richards, Zoe Holmes, E.C. Evidence for an ancient aquatic origin of the RNA viral order Articulavirales |
| title | Evidence for an ancient aquatic origin of the RNA viral order Articulavirales |
| title_full | Evidence for an ancient aquatic origin of the RNA viral order Articulavirales |
| title_fullStr | Evidence for an ancient aquatic origin of the RNA viral order Articulavirales |
| title_full_unstemmed | Evidence for an ancient aquatic origin of the RNA viral order Articulavirales |
| title_short | Evidence for an ancient aquatic origin of the RNA viral order Articulavirales |
| title_sort | evidence for an ancient aquatic origin of the rna viral order articulavirales |
| topic | Articulavirales Cnidaria evolution influenza virosphere Animals Humans Phylogeny RNA Viruses Influenza, Human Invertebrates Orthomyxoviridae RNA Evolution, Molecular RNA, Viral Mammals Animals Mammals Humans Invertebrates RNA Viruses Orthomyxoviridae RNA RNA, Viral Evolution, Molecular Phylogeny Influenza, Human |
| url | http://purl.org/au-research/grants/arc/LP160101508 http://hdl.handle.net/20.500.11937/96165 |